A study in fruit flies finds that restricting protein early in development can extend adult lifespan. The effect involves Lsp2, a storage protein that carries part of the larval nutritional history into adulthood and influences protein production.
A study of 18 cross-functional practitioners found that an AI-assisted design tool helped teams identify more potential harms than standard worksheets. The tool used shared planning blocks, checklists and simulated user perspectives to support early discussion of responsible AI concerns.
Researchers analysed double-blind randomised trials of adults with major depressive disorder to compare 10 antidepressants with placebo during the first eight weeks of treatment. Some medicines were associated with longer QTc intervals, a heart rhythm measurement, but the analysis did not find higher rates of early major cardiovascular events or non-suicidal death compared with placebo.
Researchers analyzed more than 6.3 million nuclei from the dorsolateral prefrontal cortex of 1,494 donors, including people with eight brain disorders and neurotypical controls. The atlas shows shared cellular changes across diseases, as well as disease- and stage-related differences in Alzheimer’s disease.
Researchers developed a neural-network design that enforces exact Lorentz symmetry with minimal additional computational overhead. They applied it to graph-based networks and transformers for particle-physics tasks including amplitude prediction, event generation and identifying jets from top quarks.
Different parenting styles in two stickleback types may help keep them genetically distinct. The study found that hybrid fathers showed poorly regulated care, which coincided with lower survival among the offspring they raised.
Researchers studied 4,695 very preterm infants in Sweden and compared outcomes among those who did and did not receive a three-strain probiotic supplement. Probiotic exposure was associated with lower rates of death and necrotizing enterocolitis, a serious intestinal disease, but was not clearly associated with culture-confirmed sepsis.
Two room-temperature lutetium-ion clocks achieved fractional frequency uncertainties near one part in 10¹⁹ and agreed in a direct comparison. The result supports efforts to improve international timekeeping and develop a future definition of the second.
A review of laboratory, industrial and computer studies finds that co-firing 20%–30% ammonia with coal is feasible in existing coal-fired boilers. Higher ammonia shares may raise nitrogen-oxide emissions and lower boiler efficiency, making fuel-injection design and air staging important.
Among 426 people living with HIV in Nanning, China, better sleep was associated with higher health-related quality of life. Statistical analyses suggested that depression and anxiety explained much of this relationship, although the study cannot show that poor sleep causes either condition.
In an 80-day experiment in Kampala, Uganda, shading reduced the output and efficiency of a 40-watt solar panel. Paper reduced current, power and efficiency more than comparable layers of Ficus lyrata leaves, pointing to the practical importance of cleaning and panel placement.
This narrative review examined research on oral effects reported in people taking systemic isotretinoin for acne. It found that reduced saliva, dry mouth, chapped lips, and other dryness-related symptoms were the most consistent findings, while evidence about cavities and gum health was less uniform.
A study of routine hoof-trimming records from Southern Italian dairy farms found that lesions were more common on cows’ hind feet, especially the outer hind claw. Digital dermatitis was the most frequently recorded lesion among 11,408 lesions.
A review of quantum chromodynamics surveys what scientists have learned about the phases of matter that existed about 10 microseconds after the Big Bang. It focuses on particle production, fluctuations and comparisons between collision data and theoretical predictions.
This systematic review examined whether educational activities in medical school influence students' emotional empathy. The eight included studies reported some effects, but results differed across types of empathy and across interventions, so the overall findings remain uncertain.
