Antidepressant prescribing increased from 1997 to 2023 for autistic and non-autistic adults in UK primary care records, but it rose faster among autistic adults. By 2023, 30% of autistic adults had been prescribed an antidepressant, compared with 14.7% of non-autistic adults.
Researchers reconstructed how an upstream glacial lake’s outburst triggered the failure of a second lake, devastating Thame Village in Nepal on 16 August 2024. They estimate that the flood released about 600,000 cubic metres of water and reached the village within 22 to 32 minutes.
Researchers studied how SGLT2 medicines might affect the heart, using heart tissue and cells from people with heart failure, purified laboratory components, and computer modeling. They found that the medicines activated an enzyme involved in making coenzyme A, a substance needed for several fuel-use pathways, but this study did not test patient outcomes or establish that the mechanism explains clinical benefits.
In a study of 159 emerging adults, efforts to increase positive emotions were linked to improved emotions, while efforts to reduce them were linked to the opposite pattern. People used these strategies more when their emotions were more intense, whether positive or negative.
An AI system designed for damaged South Indian palm-leaf manuscripts reported 97.4% word accuracy and 98.6% character accuracy on an archival corpus of 1,250 folios. It also reported 99.4% accuracy in identifying authentic palm-leaf manuscripts.
Computer tools and laboratory tests often agree on the effects of genetic changes, but a study of 37 human proteins found that their disagreements follow consistent patterns. The results show how protein features, laboratory design and the type of variant can shape those differences.
This 2026 guideline reviews human-participant research on rehabilitation and recovery after adult stroke. It replaces a 2016 guideline and updates recommendations across areas including medical problems, falls, technology-assisted rehabilitation, caregiver support, work, and driving. The abstract does not report patient outcomes or numerical results.
A laser-treated, glassy layer at the electrolyte interface improved the stability of solid-state lithium-metal batteries. In tests, the cells cycled for more than 2,000 hours, while lithium-cobalt-oxide cells retained a capacity of 101.9 mAh per gram after 800 cycles at 4.5 volts.
People can interpret the same general statement in different ways, yet generic language may still pass on broad knowledge. Across three experiments, a model in which such statements have an uncertain threshold best explained participants’ varied interpretations of new generic claims.
Some black holes in the early universe appear unusually massive compared with the galaxies around them. A modelling study suggests that brief, repeated bursts of rapid feeding, triggered by major galaxy mergers, could explain this pattern and the brightness of some active black holes seen by JWST.
Researchers developed an AI-based method for reconstructing changing radio images of black-hole jets as continuous videos. Applied to repeated observations of the blazar 3C 345, it estimated the local, instantaneous motion of plasma rather than tracking only separate jet features.
China’s expansion in electric vehicles illustrates the goals and progress of its Dual Circulation Strategy, according to a study in Asia Europe Journal. The authors conclude that the European Union needs a multilayered industrial strategy, including more production and innovation at home, to compete with China.
Doctors used ultrasound, gentle larval removal and DNA sequencing to diagnose a rare Hypoderma sinense infestation in a child from a cattle-raising region of China. The case shows how this livestock-associated parasite can resemble common skin infections.
In trained mice, deep-layer neurons in the auditory cortex developed categorical responses to sounds that differed in their temporal rate. These neurons also carried strong signals related to the animals’ choices, linking sound classification with behavior.
A study found that increases in online mentions of the Benadryl Challenge were followed by a significant rise in adolescent-related calls to US poison centers about diphenhydramine. Those calls remained elevated for more than 25 days after the first spike in online mentions.
