Fare-free transit riders were much more sensitive to fare reinstatement than to increases in travel time, according to a 2024 survey across five U.S. agencies. The study estimates that half of new riders in its sample could stop riding if fares exceed $1.30.
This meta-analysis examined 38 studies involving 2,170 people with relapsed or treatment-resistant peripheral T-cell lymphoma. Regimens containing an epigenetic drug had tumor response rates similar to conventional chemotherapy, but the studies reported higher one-year progression-free and overall survival rates with the epigenetic-containing regimens. Because the comparisons were based mainly on separate cohorts rather than randomized trials, the results show an association rather than proof that one approach caused better outcomes.
Researchers used a porous silica film to increase the amount of DNA produced on an electrochemical chip. The platform synthesized 121-letter DNA strands and encoded, wrote and recovered digital information with error correction.
AlphaFold3 reliably identifies disorder in individual proteins, matching AlphaFold2 and specialized prediction tools. But its results for assemblies of disordered proteins vary substantially between runs, making success difficult to predict from interface features alone.
Researchers evaluated three AI systems on hundreds of molecules bound to a SARS-CoV-2 protein and in three prospective drug screens. The results suggest that combining AI-based predictions with traditional docking may help prioritize candidates, although no single approach worked best in every test.
A critical review of geographical research argues that Latin American activism cannot be understood through territory alone. The authors propose “political space” as a way to examine movements’ activity across formal, informal, symbolic and material arenas.
Researchers mapped the synaptic connections of hormone-producing neurons in the adult fruit-fly brain. The analysis identified corazonin-producing neurons and a downstream partner that influence egg-laying, while also showing how signals from taste, smell and digestive-system neurons reach the network.
The European Union’s land carbon sink is not strengthening as quickly as climate-neutrality plans assume. Recent projections point to a 40–55 million-tonne gap to the EU’s 2030 target, while disturbances, harvesting and biomass demand could further reduce land-based removals.
A new article argues that territory in Abya Yala/Afro/Latin America is not only a fixed area defined by borders. It can also describe overlapping worlds and social practices through which subalternised groups seek autonomy, security and different ways of living.
In experiments on a six-metre carbon-dioxide pipeline with bends, joints and valves, sound sensors detected leaks and located their sources. The researchers estimated annual savings of $225,482 for monitoring one valve and about $18.9 million for monitoring pipelines, using December 2025 carbon-dioxide prices.
Researchers made water-repelling, oil-attracting copper oxide powders and a copper oxide-coated metal mesh without using organic surface modifiers. The mesh separated a chloroform–water mixture with about 98% efficiency, while the powder selectively adsorbed oil from water.
A study in China identified recurring patterns in seismic, magnetic and ionospheric data before numerous major earthquakes. The researchers say these “seismo-ripples” could provide estimates of an earthquake’s magnitude, location and timing, but the method remains limited by monitoring coverage, especially for earthquakes beneath the ocean.
Laboratory experiments suggest that taurine can regulate transthyretin, a protein involved in thyroid hormone transport and several amyloid diseases. Taurine increased transthyretin’s affinity for thyroid hormone and showed anti-aggregation effects, but its potential as a treatment has not been tested in people.
Researchers reviewed 10 retrospective studies involving 416 human fetuses with isolated pleural effusion, meaning fluid had built up around the developing lungs. After pleuro-amniotic shunting, pooled estimates suggested survival in about two-thirds of cases and resolution of fetal hydrops in about three-fifths, but preterm birth and other complications were also common.
A systematic review finds that internet services, social media, social trading platforms and trading apps shape how retail investors find information, make decisions and place trades. The same tools may contribute to information overload, overconfidence, frequent trading and herd behavior.
