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Abstract editorial illustration accompanying the article: Green-made nickel-doped zinc oxide stops bacteria and blocks key virulence genes

Green-made nickel-doped zinc oxide stops bacteria and blocks key virulence genes

Nickel-doped zinc oxide nanoparticles were made using an extract from Salvia hispanica. In lab tests, they inhibited bacterial biofilms and reduced the activity of several virulence genes, while also triggering apoptosis and cell-cycle arrest in cancer cells. The researchers also report stronger antibacterial effects against Staphylococcus aureus than against normal cells’ growth.

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Abstract editorial illustration accompanying the article: Earth’s earliest clues and lab chemistry suggest no single place made life

Earth’s earliest clues and lab chemistry suggest no single place made life

A review of evidence from Earth’s Hadean era and experiments on prebiotic chemistry finds that no single environment on early Earth appears to meet all the conditions needed for life to begin. Instead, the paper argues that multiple, connected processes across different settings likely helped build and stabilize the molecules that later became biology.

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Abstract editorial illustration accompanying the article: AI tool uses emergency triage data to predict suicide risk within 30 days

AI tool uses emergency triage data to predict suicide risk within 30 days

A study in Scientific Reports tested an AI system that predicts suicide-related behaviour within 30 days of an emergency department visit using structured triage information available at admission. The best-performing model, a LightGBM system, showed AUROC 0.88 and good recall on an independent test set, and highlight likely drivers such as prior psychiatric history, age, and physiological variables.

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Abstract editorial illustration accompanying the article: New analysis identifies risk factors for chronic kidney disease after unilateral kidney removal
Health & Medicine
High evidenceReview

New analysis identifies risk factors for chronic kidney disease after unilateral kidney removal

Researchers systematically reviewed and pooled data from 26 adult cohort studies on developing chronic kidney disease (CKD) after unilateral nephrectomy. Among adults with preserved preoperative kidney function (eGFR ≥ 60 mL/min/1.73 m²), several baseline factors—such as older age and diabetes—and surgical approach were associated with higher odds of incident CKD.

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Abstract editorial illustration accompanying the article: Rain “pulses” after drought drive nitrogen gas spikes more than soil type

Rain “pulses” after drought drive nitrogen gas spikes more than soil type

Mediterranean dryland crops face cycles of drought and then sudden rain. In a year-long field experiment, researchers found that the biggest bursts of nitrogen pollution in the form of nitrous oxide and nitric oxide followed rewetting, especially when plants had been stressed by drought. Soil texture changed how much inorganic nitrogen built up, but it did not lead to proportionally larger gas spikes.

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Abstract editorial illustration accompanying the article: AI designs residential yards that better balance comfort, looks, access, and nature

AI designs residential yards that better balance comfort, looks, access, and nature

A study in Scientific Reports describes an AI framework that generates different residential landscape layouts while explicitly weighing trade-offs among comfort, appearance, accessibility, and ecological value. Tested on three parcels in Changsha, China, the approach produced more diverse, realistic-looking morphologies and found optimized schemes that, on average, scored 6.2% above professional human benchmarks on a combined index.

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Abstract editorial illustration accompanying the article: Study finds blood inflammation markers did not reliably predict antifungal resistance in vaginal yeast infections
Health & Medicine
Low evidenceHuman study

Study finds blood inflammation markers did not reliably predict antifungal resistance in vaginal yeast infections

Researchers studied whether circulating inflammatory biomarkers in blood track with antifungal susceptibility in women with culture-confirmed vulvovaginal candidiasis. In this retrospective observational cohort of 163 adults, most blood marker levels did not differ between women with antifungal-resistant versus susceptible Candida isolates. Overall, the findings suggest these markers may not be a substitute for direct antifungal susceptibility testing in this localized infection.

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