University of Toronto

An Agency-Specific Project Authoring Advisor: LLM-Based RAG System with Automatic Prompt Optimization Method

Abstract Despite the vast potential of large language models (LLMs) in specialized fields, their application in architecture, engineering, and construction (AEC) has been hindered by several challenges, including inaccurate information retrieval, limited access to domain informat...

Redesigning 9-1-1 Paramedic Pathways: Evaluation of the IMPACC Model of Care

OBJECTIVES Paramedic services remain organized around rapid response, time-sensitive events, and hospital conveyance despite increasing 9-1-1 use for lower-acuity and undifferentiated presentations. There is a need to improve the alignment of paramedic services for patients seeki...

Adipocytes as a Mechanistic Link Between Incretin-Based Therapies and Hair Loss

The physiological effects of glucagon-like peptide-1 receptor agonists (GLP-1RAs) and dual glucose-dependent insulinotropic polypeptide (GIP)/GLP-1RAs extend beyond glucose metabolism and body weight regulation. Accumulating clinical evidence has highlighted an association betwee...

Personalized Ultrafractionated Stereotactic Adaptive Radiotherapy in Lung Cancer and Lung Metastases: A Systematic Review

Background/Objectives: Personalized ultrafractionated stereotactic adaptive radiotherapy (PULSAR) delivers high-dose stereotactic radiation as temporally separated pulses, permitting interval response assessment, adaptive replanning, and integration with systemic therapy. Its rol...

Identifying and characterizing eating disorder discourse on Chinese social media: a machine learning approach

Eating disorders (EDs) are severe psychiatric conditions with high mortality and substantial medical complications. In China, underdiagnosis and low treatment engagement hinder timely intervention. Social media platforms provide a naturalistic lens into ED-related experiences, ye...

Na2CO3 induced crystal growth assisted ilmenite reduction and cyclic wet magnetic separation coupling to achieve efficient separation of titanium and iron

In this study, we employed a Na 2 CO 3 -enhanced reduction process coupled with cyclic wet grinding and magnetic separation for effective utilization of low-grade ilmenite. The process was designed to produce a high-grade titanium-rich product. This study systematically investiga...

Interventions to increase involvement of primary care clinicians in providing palliative care: A scoping review

Background: It is recognized that primary care clinicians have a critical role in ensuring access to palliative care in health systems. When primary palliative care has been examined at the system level, provision is highly variable, making the study of best practices challenging...

Palladas, Praxiteles’ Parian Eros and Constantine’s transformation of pagan images in Constantinople

Abstract An argument for locating Palladas’ floruit in the early fourth century, first advanced in 2009, has met with a mixed reception. This article buttresses the argument and continues the work of integrating this evidence into accounts of the early fourth century. The topic i...

International Protocol for the Study of Amorphous Charred Objects in Archaeology (IPSACO 1.0)

Abstract Archaeobotanists around the world increasingly recognise that, alongside commonly studied materials such as seeds, fruits, wood charcoal, and chaff, archaeobotanical samples also contain fragments of carbonised organic (and sometimes inorganic) matter that vary in shape...

Religious antinatalism: a rare breed

Abstract This article examines the relationship between religion and antinatalism – the view that it is wrong to create new sentient beings. Many people reject antinatalism on religious grounds. In this paper, I respond to such a rejection. First, I argue that antinatalism is not...

The Impact of the Number and the Size of Clusters on Prediction Performance of the Stratified and the Conditional Shared Gamma Frailty Cox Proportional Hazards Models

ABSTRACT Researchers in biomedical research often analyze data that are subject to clustering. Development and validation of risk prediction models generally assumes independence of observations. For survival outcomes, the Cox proportional hazards (PH) regression model is commonl...

Analyzing Initialization Strategies for the Local Unitary Cluster Jastrow Ansatz within the Quantum-Centric Supercomputing Framework

Abstract In this study, we analyze the choice of local unitary cluster Jastrow (LUCJ) ansatz initialization and the sensitivity of the sample-based quantum diagonalization (SQD) algorithm within the quantum-centric supercomputing (QCSC) framework. We examine six initialization st...

Why Integration Compounds A Threshold Theory of Technology Transfer and Global Value Chains

The returns to integration into global value chains split by level of development: integration raises productivity and growth in emerging and faster-growing economies, but not in slower-growing developing ones. The split is established, but no formal model accounts for its conseq...

Real-World Shelf Life of Epinephrine Auto-Injectors in Canada: Implications for Renewal Frequency and Patient Burden

Although patients in Canada at risk of anaphylaxis are recommended to maintain access to two in-date epinephrine auto-injectors (EAIs) at all times, underuse during emergencies remains common. Multiple factors contribute to this gap, but the impact of real-world shelf life has be...

Respiratory Syncytial Virus–Related Hospitalizations Among Infants Receiving Nirsevimab

Importance Respiratory syncytial virus (RSV) is a leading cause of hospitalization among infants. Nirsevimab, a long-acting monoclonal antibody that protects against severe RSV, was publicly funded for all infants in the Canadian provinces of Ontario and Quebec starting in the fa...

Migrations and Mobilities Along China's Belt and Road: Emergent Geographies and Evolving Connectivities

The authors declare no conflicts of interest. Data sharing not applicable to this article as no datasets were generated or analysed during the current study.

Enabling employment: findings from a qualitative study on disability and employment in Canada, United States, United Kingdom, France and Belgium

Despite the UN CRDP, national anti-discrimination laws, and government employment programs, the ‘disability employment gap’ remains in most countries. This article outlines the results of a research project that examined the factors that enable disabled people to obtain and maint...

Muometric Data Modulation and State Synchronization Through Obstructed Subsurface Media: A Theoretical Framework, Channel Physics Model, and Protocol Design

Conventional radio-frequency (RF) and acoustic communication channels suffer severe absorption and scattering when traversing dense rock and collapsed subsurface infrastructure [4, 5]. While relativistic muons (µ ±) possess extreme penetration capabilities, their application as p...

Muometric Data Modulation and State Synchronization Through Obstructed Subsurface Media: A Theoretical Framework, Channel Physics Model, and Protocol Design

Conventional radio-frequency (RF) and acoustic communication channels suffer severe absorption and scattering when traversing dense rock and collapsed subsurface infrastructure [4, 5]. While relativistic muons (µ ±) possess extreme penetration capabilities, their application as p...

From past, persisting, and consolidating ecologies of segregation to ecologies of repair

Across the United States and Europe, urban and periurban spaces have historically been shaped by land dispossession and enclosure that systematically exclude marginalized, non-White communities from the benefits of society, including access to nature. These dynamics, which have p...