University of Toronto

Figli della malinconia e della notte : Exploring Anna Maria Ortese’s Sprites and Sorrowful Childlike Creatures

This article explores a recurring literary archetype in the fantastic universe of Anna Maria Ortese: the sorrowful, childlike figure, with particular focus on the sprite (folletto). Beginning with Il Monaciello di Napoli (1940), Ortese traces a genealogy of suffering spirits that...

Orthobiologic Injections Adjunctive to Cartilage‐Preserving Surgery May Improve Outcomes for Focal Knee Chondral Defects: A Systematic Review of Randomized Controlled Trials With Subgroup Meta‐analyses

Purpose To perform a systematic review evaluating the efficacy of orthobiologic injections as adjuncts to cartilage‐preserving surgery in improving clinical, radiographic, and histologic outcomes in adults with focal knee cartilage defects. Methods Four databases (PubMed, MEDLINE...

How Academic Researchers Align Values and Methodology: A Qualitative Inquiry of Equity-Informed Micro-Practices

Background Academic researchers conducting participatory research often navigate complex institutional, administrative, and funding constraints that limit their ability to actualize commitments to equitable practice. In response, many researchers adopt informal ad hoc strategies...

The ideology of access: Young adult experiences in transition from Literacy and Basic Skills to postsecondary education

Expanding the forms of educational access available is one response to crises in unemployment, housing, migration, pandemics, wealth disparity, and discrimination. Young, racialized, immigrant adults are often the target of efforts to expand access. I analyze the social relations...

Association between Glycemic Control and Survival in Patients with Type 2 Diabetes on Peritoneal Dialysis

Background: Diabetes is the leading cause of kidney failure globally affecting 40% of people receiving peritoneal dialysis (PD). High quality data on the potential impact of improving glycemic control is needed to inform the current recommendations to individualise HbA 1C targets...

Outcomes of Acute Coronary Syndrome in Africa: a systematic review and meta-analysis

Acute coronary syndrome (ACS) represents an escalating public health crisis in Africa, driven by an ongoing epidemiological transition. Unlike in high-income countries, ACS in Africa disproportionately affects a younger, economically active demographic, imposing a severe socioeco...

Pregnancy after haematopoietic stem cell transplantation: likelihood, risks, and management

PURPOSE OF REVIEW: Advances in haematopoietic stem cell transplantation (HSCT) have improved long-term survival, making fertility and reproductive health increasingly important aspects of survivorship. This review summarizes current evidence regarding fertility after HSCT, fertil...

Optimized Brain Functional MRI for Patients With Deep Brain Stimulation Systems

BACKGROUND AND OBJECTIVES: Deep brain stimulation (DBS) is an established neuromodulation therapy for Parkinson disease and other neurological disorders. Active DBS–functional MRI (fMRI) enables visualization of circuit engagement and may provide objective biomarkers of therapeut...

Lower Bounds for Set-Multilinear Branching Programs

Abstract. In this paper, we prove super-polynomial lower bounds for the model of sum of ordered set-multilinear algebraic branching programs, each with a possibly different ordering ([Formula: see text]). Specifically, we give an explicit [Formula: see text]-variate polynomial of...

Studying Physical–Virtual Hybridisation in Everyday Life Through the Time‐Geographic Project Concept

Abstract This study proposes a time‐geographic approach for operationally defining and quantitatively measuring the physical–virtual hybridisation of daily activities. While hybridisation has been proposed to move beyond separating the usage of information and communications tech...

Between hospice and harm reduction: mixed methods analysis of barriers to palliative care for people who inject drugs

People who inject drugs (PWID) experience a high burden of life-limiting illness and barriers to palliative care. Inpatient hospices may reduce these inequities, but little is known about their policies, practices, and preparedness to care for PWID. We examined Ontario hospices a...

Adding epistemic influence to task-based AI disclosure

Dear EditorCleland and colleagues provide a practical AMEE Guide on disclosure of artificial intelligence (AI) use in academic publishing [1]. Rikers subsequently argued that the Guide’s threshold ...

Conceptualizations of compassion in the context of dementia caregiving: A scoping review protocol

Background Compassion is widely recognized as a vital component of dementia caregiving, yet its conceptualization, definition, and operationalization remain inconsistent across contexts. In dementia caregiving, compassion is often conflated with empathy, emotional labor, and rela...

Reinforcement Learning for Intensity Control: An Application to Choice-Based Network Revenue Management

Learning from Snapshots Is Not Enough: An Even-Driven Continuous-Time Reinforcement Learning Framework Revenue management systems evolve continuously, but reinforcement learning often requires dividing time into a fixed grid. Fine grids improve accuracy but increase computation;...

Might cannabis Legalization Have Affected Public Health-Relevant Alcohol- and Tobacco-use Outcomes in Canada?

Canada legalized the non-medical use and supply of cannabis in 2018. The public health-relevant outcomes of cannabis legalization documented to date have been mixed, with decreases in cannabis-related crime and illegal distribution markets, while with increases for many – acute a...

An Agency-Specific Project Authoring Advisor: LLM-Based RAG System with Automatic Prompt Optimization Method

Abstract Despite the vast potential of large language models (LLMs) in specialized fields, their application in architecture, engineering, and construction (AEC) has been hindered by several challenges, including inaccurate information retrieval, limited access to domain informat...

From Awareness to Action: Co‐Designing Culturally Safe and Equitable Rehabilitation in Canada – Protocol for the Two‐Phase Ireach Qualitative Study

ABSTRACT Background Inequities in access, engagement, and outcomes persist across outpatient rehabilitation services in Canada, disproportionately affecting Indigenous Peoples, newcomers and refugees, gender‐ and sexually‐diverse individuals, and people with lower income. Althoug...

Identifying and characterizing eating disorder discourse on Chinese social media: a machine learning approach

Eating disorders (EDs) are severe psychiatric conditions with high mortality and substantial medical complications. In China, underdiagnosis and low treatment engagement hinder timely intervention. Social media platforms provide a naturalistic lens into ED-related experiences, ye...

Sex Disparity in Enrolment to Clinical Trials for Onchocerciasis and Trachoma

To determine whether female enrolment in randomized interventional clinical trials for onchocerciasis and trachoma reflects the real-world sex distribution of disease burden, and to evaluate sex-based differences across trial characteristics. We performed a cross-sectional analys...

Adipocytes as a Mechanistic Link Between Incretin-Based Therapies and Hair Loss

The physiological effects of glucagon-like peptide-1 receptor agonists (GLP-1RAs) and dual glucose-dependent insulinotropic polypeptide (GIP)/GLP-1RAs extend beyond glucose metabolism and body weight regulation. Accumulating clinical evidence has highlighted an association betwee...