University of Southern California

Combined Associations of Glycoprotein Acetylation With Lipoprotein (a) and hs‐CRP (High‐Sensitivity C‐Reactive Protein) on Risk of Cardiovascular Disease in MESA

BACKGROUND: Higher plasma glycoprotein acetylation (GlycA) concentrations are associated with an increased risk for incident cardiovascular disease (CVD). We investigated the combined associations of GlycA with lipoprotein (a) (Lp[a]) and hs-CRP (high-sensitivity C-reactive prote...

Comparison of Biometric Measurements Between Anterior Segment Hyperparallel and Swept-Source Optical Coherence Tomography

Purpose: To evaluate the inter-device agreement between hyperparallel optical coherence tomography (HP-OCT) and swept-source OCT (SS-OCT) in quantitative anterior segment parameters. Methods: Phakic subjects aged ≥40 years were consecutively recruited at a tertiary eye hospital....

Promoting arm movement practice with a novel wheelchair armrest early after stroke: a randomized controlled trial

Abstract Background Chronic upper extremity (UE) impairment is common after stroke. This study aimed to evaluate both the feasibility and preliminary clinical effects of Boost, a novel wheelchair-mounted rehabilitation device designed to assist individuals in UE motor recovery du...

Building a Specialty: Immigrant Jewish Surgeons and the Institutions of American Plastic Surgery

American plastic surgery acquired its professional society in 1931, organized principally by Jacques Maliniac of Warsaw, with Gustave Aufricht of Budapest among its founders, and its journal in 1946, established largely through the efforts of Aufricht. Both were Jewish immigrants...

Multiagent Assortment Optimization in Sequential Matching Markets

Motivated by the challenges faced by choice-based matching platforms, in this work, we study a generalization of the two-sided assortment optimization model. Specifically, this model consists of two sides (e.g., customers and suppliers) who have preferences over the opposite side...

Physical Parameters Influencing the Rate of Subretinal Injection: A Microfluidic Analysis

Purpose: Subretinal injection during vitrectomy has become an important technique owing to the growing number of cell and gene therapy trials for retinal disease. Reducing the injection rate can mitigate trauma or shear forces on the retinal pigment epithelium, yet many surgeons...

Joint Optimization of Retrieval-Augmented KV Caching and Adaptive Speculative Decoding for Autoregressive Generation

Abstract Retrieval-assisted key–value (KV) reuse and speculative decoding remove different costs, but their naive composition can leave draft and verification overhead after prefill is shortened. RAKV-ASD combines exact causal prefix validation with a measured controller that sel...

Emotional reactivity and decision-making under social deprivation: the role of trait anxiety during quarantine

Abstract Social isolation measures enforced during the COVID-19 pandemic highlighted the importance of the social environment in shaping affective states and decision-making. However, the day-to-day experience and psychological recovery from social deprivation, especially among i...

Learning Optimal Classification Trees Robust to Distribution Shifts

We consider the problem of learning classification trees that are robust to distribution shifts between training and testing/deployment data. This problem arises frequently in high stakes settings such as public health and social work where data is often collected using self-repo...

The Euler Equations with Variable Coefficients

Abstract. We establish local-in-time existence for the Euler equations on a bounded domain with space-time dependent variable coefficients, given initial data [Formula: see text] under the optimal regularity condition [Formula: see text]. In the case [Formula: see text], we furth...

Caregivers in a Haystack? Informatics‐Driven Clinical Trial Enrollment of Dementia Caregivers at Medical Visits

BACKGROUND: Caregiving status is not routinely documented during clinical care, rendering caregivers difficult to identify for research and supportive interventions. We describe two informatics-based strategies for identifying dementia caregivers at their own or their care recipi...

Organizational Zemblanity: How Organizational Learning Can Reinforce Rigidity, Error, and Misalignment

Organizational learning can help organizations improve and adapt, but it can also reinforce error and misalignment. These negative outcomes are often interpreted as implementation problems or as signs of incomplete learning. We instead examine the possibility that dysfunction can...

A Unified Quadratic Scaling Relation Between Potency and Local Earthquake Magnitudes for −1.8 ≤ M L ≤ 7.5

Abstract Quantifying earthquake size across scales requires linking physical source parameters to empirical magnitude measures, especially for microearthquakes where attenuation, scattering, and instrumental limitations complicate source characterization. We combine regional resu...

Global Incidence of All-Cause Dementia

Importance Global dementia incidence estimates are limited by underrepresentation of low- and middle-income countries and heterogeneous analytic methods. Due to these limitations, true understanding of the global dementia landscape remains incomplete. Objective To identify dement...

Identity Safety Cues and Belonging among Graduate Students Across Racial Groups

Graduate education remains a racially stratified environment in which students’ sense of belonging has important implications for persistence, well-being, and professional development. Drawing on survey data from graduate students at a large, research-intensive university, this s...

From protogalaxy through thick and thin: Why did the Milky Way evolve in three kinematic phases?

Abstract APOGEE and Gaia data suggest the Milky Way’s kinematic structure evolved through three distinct phases: a disordered protogalaxy, which ‘spun up’ into a thick stellar disk, and then ‘cooled down’ to a final cold, thin stellar disk. We use a suite of FIRE-2 cosmological z...

Neonatal Dried Blood Spot Metabolomics Reveals Signatures of Early‐Onset Myeloproliferative Neoplasms

ABSTRACT The etiology of myeloproliferative neoplasms (MPN) is poorly understood. We investigated the possible role of early‐life exposures in the pathogenesis of MPN diagnosed among children and young adults in a population‐based case–control study in California. Untargeted meta...

Distinct biological and biomechanical features in jaw and knee cartilage contribute to their degenerative susceptibility

The temporomandibular joint (TMJ) and knee joint are both prone to degenerative diseases such as osteoarthritis (OA); however, TMJ-OA generally manifests earlier than knee OA, with underlying mechanisms largely unknown. In this study, we explored potential explanations through co...

Microstructure‑Dependent Phase Transformations Under High‑Pressure Laser Heating in Additively Manufactured AlCrFe 2 Ni 2

Additive manufacturing (AM) produces microstructures the behavior of which under extreme conditions remains largely unexplored in chemically complex alloys. Here, we investigate the high‐pressure and high‐temperature response of an AM AlCrFe 2 Ni 2 alloy fabricated at two scan sp...

Diabetic Peripheral Neuropathy: Implementing Guidelines into Practice

Diabetic Peripheral Neuropathy (DPN) is a common and debilitating complication of diabetes, affecting up to 50% of patients. Early identification and management of DPN are crucial to minimize complications and maintain patient quality of life. Multiple guidelines have been develo...