University of Copenhagen

Device-Measured Physical Activity, Sedentary Time, and Cardiometabolic Risk Markers in Youth

Importance The evidence for benefits of higher physical activity and lower sedentary time on the cardiometabolic risk profile in youth is based on cross-sectional and small prospective studies. Objective To determine the prospective associations between device-measured physical a...

Intraglandular treatment with adipose-derived mesenchymal stem cells in patients with xerostomia due to Sjögren’s disease—a study protocol for aphase 1, triple-blinded, randomized, clinical trial

Xerostomia (the subjective feeling of dry mouth) is a prominent symptom in Sjögren’s disease and often related to hyposalivation. Xerostomia and hyposalivation negatively affect the oral health and have a significant negative impact on general health and overall quality of life....

Post-Complexation Synthesis of Responsive Polymer Nanoparticles Functionalized with Kinetically Inert Europium(III) Complexes for Bicarbonate Sensing

Abstract Engineering nanomaterials to perform a specific function requires control of the complex chemistry involved in the formation of the nanomaterial and thus control of the resulting architecture. Here, we explored the sequence of steps required to make responsive nanopartic...

A Multilevel Spiral Model of Post-Traumatic Growth: Integrating Individual, Relational, and Collective Pathways of Transformation

Abstract Trauma research has most often been studied through the harm it inflicts on individuals and has largely centered on individual events and on the harm they can cause. Yet much trauma is complex, continuous, collective, and intergenerational — including systemic and struct...

Insect outbreak progression over three years shapes biogenic volatile emissions in a mountain birch forest

Abstract Geometrid moth outbreaks are important natural disturbances in mountain birch ( Betula pubescens ssp. czerepanovii ) forests of northern Fennoscandia and are expected to intensify with climate change. Impacts of these outbreaks and moth herbivory on biogenic volatile org...

Embodied Cognition in Science Teacher Education: A Phenomenographic Analysis of Science Teachers’ Experiences When Using Role-play to Engage with Different Philosophical Traditions of Embodiment

Abstract Embodied cognition (EC) theory has become increasingly prevalent in k-10 science education but remains largely theoretical or divorced from authentic classroom practices. We address this gap in the literature by examining how EC can be systematically brought into science...

Click‐to‐Release Reactivity of Quaternary Anilinium Tetrazines Enables Cascade Assembly of Multifunctional Biomolecular Scaffolds

Click chemistry has evolved from its origins in forming covalent connections to also include breaking bonds, cleaving linkers, and liberating cargo, creating broad applications in chemical biology and biomedicine. The reaction sequences that drive these tools are complex, and thu...

Temperature Dysregulation Following Intrathecal Morphine for Cesarean Delivery Patients—A Scoping Review

ABSTRACT Background Intrathecal morphine is widely used for postoperative analgesia following cesarean delivery. However, intrathecal morphine's potential association with hypothermia remains uncertain, although hypothermia may adversely affect maternal recovery and comfort. This...

Occupational Exposure to Nickel and Cobalt From Hairdressing Tools: A Cross‐Sectional Study in 58 Danish Salons

ABSTRACT Background Hairdressers frequently perform wet work, which weakens the skin barrier. Repeated skin contact with metallic tools introduces an occupational allergen exposure. However, data on nickel and cobalt release from commonly handled cutting tools remain limited. Obj...

Consumers with high shares of organic food consumption are more likely to feel obliged to reduce the climate impact of their food – a segment-level analysis based on two separate datasets

Abstract This study investigated the extent to which consumers with high organic consumption are more climate-oriented than segments of consumers with low organic consumption. We did this by identifying comparable organic Light user and Super user segments in two separate dataset...

The SocMed Database: coverage and clinical characteristics of individuals seen in social medicine in the capital region of Denmark

This study aimed to describe The SocMed Database, its content, completeness, and representativeness compared with the Danish National Patient Register (DNPR), alongside population characteristics within a biopsychosocial framework. In Denmark, Departments of Social Medicine manag...

Incidence of Culture‐Proven Neonatal Sepsis and Its Correlation With Nurse Staffing in a Level IV Neonatal Intensive Care Unit: A Six‐Year Cohort Study

ABSTRACT Aim To assess the incidence of culture‐proven sepsis and examine the correlation between positive blood cultures and nurse staffing in a Level IV neonatal intensive care unit (NICU). Methods This retrospective cohort study included neonates with ≥ 1 positive blood cultur...

Early antimicrobial therapy and clinical outcomes of left-sided Enterococcus faecalis endocarditis: a NIDUS registry study

Abstract Purpose Antimicrobial therapy of Enterococcus faecalis endocarditis treatment is challenged by high intrinsic resistance and relapse rates. Knowledge on practice patterns is warranted. We aimed to describe early-phase monotherapy and combination therapy use in E. faecali...

“Hello everybody”: when online styles go offline

Abstract Young people in Denmark spend considerable time on social media platforms such as TikTok and YouTube, engaging with vlogs, tutorials, and unboxing videos that are often in English. Drawing on a five-month ethnographic study of 20 high school students (aged 15–17) in the...

“More than medicine — but when?” A qualitative study of how general practitioners assess, negotiate, and apply social prescribing in clinical practice

Social prescribing (SP) addresses social determinants of health by linking patients in general practice to community-based, non-clinical services. Despite positive attitudes among general practitioners (GPs), uptake remains limited, and little is known about how SP is interpreted...

Leptin-sensitive hypothalamic Lepr+/Glp1r+ neurons limit hyperphagia and weight gain in diet-induced obesity

Abstract Despite loss of responsiveness to exogenous leptin in obesity, endogenous leptin continues to restrain feeding, although the neural substrates that remain sensitive and mediate this effect remain unknown. Combining spatial transcriptomics with single-nucleus RNA sequenci...

Bone Anabolic Treatment in Patients With Chronic Kidney Disease: A Systematic Review

BACKGROUND: Chronic kidney disease (CKD) associated osteoporosis leads to an increased risk of bone fracture in patients with CKD. Evidence on the efficacy and safety of anti-osteoporotic medications is limited for this group. This systematic review aimed to examine the efficacy...

Sexual and relational challenges in men and women affected by prostate cancer: a Project SEXUS study

OBJECTIVES: To examine, in a nationally representative Danish study, a comprehensive range of sexual characteristics, dysfunctions and relational challenges among men with prostate cancer (PCa) aged ≥50 years and women married to such men, compared with unaffected men and women....

Management of Type 2 Diabetes, 2026. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)

The American Diabetes Association and the European Association for the Study of Diabetes convened a panel to update the consensus statement on the management of type 2 diabetes in nonpregnant adults, published since 2006 and last updated in 2022. The target audience is the multid...

Evidence-based atlas of risk and protective factors for psychotic disorders: an umbrella review to inform personalized prognosis and prevention.

Identifying updated, evidence-based risk and protective factors for psychotic disorders is essential to advancing scientific and clinical knowledge of their etiology. Since the most recent umbrella review published in this journal, the evidence base has expanded substantially. Fo...