University of Copenhagen

EMS response time and patient outcomes in high-acuity emergency responses: a Danish matched cohort study

Emergency medical services (EMS) provide prehospital care. To reduce response times, ambulances may use lights, sirens, and traffic exemptions, increasing risks for EMS personnel and other road users. Additionally, predefined response time targets may lead to inefficient resource...

Brief video-feedback training enhances childcare professionals’ interaction skills: A cluster randomized controlled trial

High-quality caregiver–child interactions are central to children’s development in early childhood education and care (ECEC) settings. Professional development programs have been shown to improve caregivers’ interactional skills, but evidence from large randomized controlled tria...

Scoring rules with normalized upper order statistics for tail inference

Abstract This paper proposes a scoring-rule-based method for ranking predictive distributions in the Fréchet domain that is able to distinguish between different tail indices. The approach is built on normalized order statistics and exploits proper scoring rules to compare tail l...

Personal Income Progression of Informal Family Caregivers of Children and Young Adults With Mental Disorders

Informal family care for a child with a mental disorder may negatively impact work capacity and decrease income. We compare prolonged sex-specific personal income progression between informal family caregivers of children/young adults with and without mental disorders. We evaluat...

Reading the forest through patents: A Europe-wide sector analysis

Innovation will shape how Europe's Forest sector responds to growing demand for low-carbon materials and bio-based products. However, the technological composition and geographical distribution of recent patenting activity in the sector remain insufficiently documented. This stud...

The Evolution of Low-ionization Electron Densities in Galaxies across Cosmic Epochs

Abstract We investigate the low-ionization electron density in the interstellar medium (ISM) of galaxies across 0 < z < 8, derived with the [O ii ] λλ 3727, 3730 and [S ii ] λλ 6718, 6733 doublets, using both deep JWST/NIRCam/grism and NIRSpec/MSA spectroscopy. Along with ancilla...

Structural basis for size-selective perception of chitin in plants

Plants detect microbes through pattern recognition receptors that perceive conserved microbial surface motifs known as microbe-associated molecular patterns (MAMPs). Lysin motif (LysM) receptors recognize and mediate downstream responses to chitinous MAMPs. In this study, we eluc...

The Promise of Augmented Reality in Everyday Life

Augmented Reality (AR) is increasingly positioned as the next frontier in personal computing, yet how it would actually integrate into everyday life remains poorly understood. We investigate the promise of everyday AR by analyzing (1) 184 practitioner-created vision videos and (2...

Moralising geopolitics: Sexual shame and stigma in international relations

Abstract This article theorises the role of sexual shame and stigma in constituting and reproducing international order. Using Russia and the USA as illustrative cases, it argues that anti-queer politics is not an isolated domestic phenomenon but part of a broader geopolitical pr...

Constraining Dust Formation in the Superluminous Supernova 2017gci with JWST Observations

Abstract We present JWST/MIRI observations of the Type I superluminous supernova (SLSN) 2017gci obtained over 2000 rest-frame days after the supernova (SN) exploded, which represent the latest phase images taken of any known SLSN to date. We find that archival Wide-field Infrared...

Variable proficiency attainment following virtual reality cataract training: Implications for a mastery learning approach

PURPOSE: Virtual reality simulation (VRS)-based training is widely used to prepare novice cataract surgeons, yet unstandardized training regimens result in variable competence at the transition to surgery. In many settings, training follows a directed self-regulated learning appr...

Bariatric Surgery and Risk of Obesity-Related Cancer by Age and Sex

Importance Obesity is associated with elevated risks for multiple cancers. How bariatric surgery influences these risks across age and sex is insufficiently understood. Objective To evaluate the association between bariatric surgery and obesity-related cancer (breast, endometrial...

Phosphate Recovery from Arsenic-Laden Groundwater Treatment Sludge

Abstract In this work, we investigated phosphate (P) recovery via calcium phosphate (CaP) precipitation from P-rich solutions produced synthetically and derived from arsenic (As)-laden groundwater treatment sludges. We systematically altered key variables in synthetic experiments...

With whom you elaborate matters: how learning orientation impacts cross-culture and same-culture information elaboration in culturally diverse teams

Abstract Work teams are increasingly characterized by diverse cultural backgrounds. Although research has established that cultural diversity holds the potential to enhance team performance through information elaboration—the exchange, discussion, and integration of task-relevant...

Generation and Functional Characterization of Cadaver-Derived iPSC-Cardiomyocytes: A Feasibility Study Toward Functional Molecular Autopsy in Sudden Cardiac Death

Sudden cardiac death (SCD) accounts for a substantial share of deaths in young individuals. Despite postmortem pathological, toxicological, and forensic examination and molecular autopsy, many cases remain unexplained, highlighting the need for complementary approaches to investi...

Risk of malignant melanoma in hyperthyroid and hypothyroid female populations: Results from a large Danish cohort study

Introduction Experimental studies suggest that thyroid hormones may influence tumor development through endocrine and cellular signaling pathways. Although malignant melanoma (MM) is primarily associated with ultraviolet radiation exposure, the potential role of thyroid dysfuncti...

Development and Validation of a Blood Test Informed Risk Prediction Model for Lung Cancer—The Copenhagen Lung Cancer Risk Model (CPH-Lung)

Purpose Lung cancer screening reduces lung cancer mortality, but identifying high-risk individuals remains difficult. We wanted to develop a blood test–based risk model (CPH-Lung) to improve risk stratification before image-based screening. Materials and Methods We included indiv...

Higher plasma vitamin D levels are not causally associated with less age‐related macular degeneration

PURPOSE: Higher levels of plasma 25-hydroxyvitamin D have been associated with a lower risk of age-related macular degeneration (AMD). We investigated observational and potential causal associations of plasma 25-hydroxyvitamin D with the risk of AMD in two large contemporary popu...

Chronic alanine aminotransferase elevation in people with HIV : Time trends over 22 years and genetic predisposition

Abstract Introduction Chronic elevation of alanine aminotransferase (cALT) is common in people with HIV. Published reports on cALT prevalence time trends have not been uniform. It is unknown whether genetic background is associated with cALT in people with HIV. Methods cALT was d...

Mechanisms of XCR1 Membrane Trafficking and Constitutive Endocytosis

ABSTRACT Chemokines orchestrate immune cell trafficking through receptor‐mediated signalling and are implicated in inflammatory, autoimmune and neuropathic disorders. The XCL1–XCR1 axis is of particular interest because XCR1 is selectively expressed on mature conventional type 1...