Columbia University

How common is alcohol use disorder in posttraumatic stress disorder? A systematic review, meta‐analysis, and moderator analysis

BACKGROUND AND OBJECTIVES: Comorbidity between posttraumatic stress disorder (PTSD) and alcohol use disorder (AUD) complicates care, yet reported prevalence varies widely across settings and methods. We estimated AUD prevalence among adults with PTSD and identified sources of var...

Sex-specific biological aging clocks across organs and omics

Sex differentially shapes aging, neurodevelopment and neurodegenerative diseases such as Alzheimer’s disease (AD). However, most biological aging clocks (artificial intelligence-predicted age minus chronological age) were trained on sex-pooled samples and implicitly assume sex in...

Auditory associative learning drives synaptic responses in tail of the striatum spiny projection neurons

The association of cues with the absence or presence of danger is crucial to survival. The synaptic changes that enable association with the absence of danger are unknown, but a role for the tail of the striatum (TS) has been implicated. To investigate this, we conditioned mice t...

Extratropical teleconnections in a multi-model ensemble nudged towards the observed QBO

The Quasi-Biennial Oscillation (QBO), the dominant mode of interannual variability of monthly-mean zonal winds and temperatures in the equatorial stratosphere, has a significant influence on the circulation in other regions of the stratosphere and troposphere in boreal winter. To...

Constellation Dataset: Benchmarking High-Altitude Object Detection for an Urban Intersection

Abstract As smart cities evolve, privacy-preserving edge processing at traffic intersections has become essential for real-time safety applications while reducing data transmission and centralized computation. High-altitude cameras with on-device inference provide an optimal solu...

From microscopic fluctuations to susceptibility spectra: Single-molecule relaxation in glassy media

Single-molecule (SM) rotational dynamics of fluorescent probes in polystyrene near the glass transition temperature (Tg) are investigated over long times to reconstruct susceptibility spectra. The loss spectrum, commonly recorded using external field-driven (frequency-domain) spe...

Air pollution after the shutdown of US embassy monitoring

For more than a decade, US embassies and consulates provided independent, publicly accessible air-quality information in cities worldwide. In 2025, this program was abruptly suspended, generating sharp drops in the availability of trusted pollution information. We evaluate the co...

Hearing Loss Is Associated With Regional Brain Amyloid in a Late Middle‐Aged Cohort

ABSTRACT Objectives Investigate the association of hearing loss (HL), measured by pure‐tone average (PTA) and word recognition score (WRS) in the better ear, with cerebral amyloid deposition, measured with amyloid positron emission tomography (PET). Methods Two‐hundred twenty‐thr...

Molecular Evaluation of Deep Eutectic Solvents for Wet Algae Lipid Extraction and Biofuel Production

Abstract Microalgae represent promising feedstocks for biofuel production, yet cell-wall disruption remains a critical bottleneck for scaling up lipid extraction. This study evaluates four cholinium-based ionic liquids (ILs) and deep eutectic solvents (DESs) as green, energy-effi...

Finite and Infinite Weighted Exchangeable Sequences

Motivated by recent interest in predictive inference under distribution shifts, we study the problem of approximating finite weighted exchangeable sequences by a mixture of finite sequences with independent terms. Two different approaches are developed: a combinatorial approach a...

The plausible relationship between deep long-period earthquakes and volatiles: a case study of the Alaska-Aleutian arc

Abstract Deep long-period (DLP) earthquakes are observed beneath volcanoes in various tectonic settings during background activity, unrest, and eruption. The exact processes generating DLPs have been subject to ongoing debate, as they may provide insight into deep magmatic plumbi...

Maternal neighborhood deprivation and its association with early childhood neurodevelopmental impairment in extremely preterm infants

Abstract Objective Evaluate whether maternal Area Deprivation Index (ADI) is associated with neurodevelopmental impairment (NDI) at age 2 in extremely preterm infants. Study design Retrospective cohort study of infants <29 weeks’ gestation at four NICUs spanning multiple US regio...

Self-reported cannabis use following cash transfer: Estimating the short-term impacts of the Alaska Permanent Fund Dividend

Aims Researchers have hypothesized that cash transfers affect substance use through two competing pathways: relieving financial strain which could reduce use, or expanding spendable income, which could increase use. We tested whether payments from the Permanent Fund Dividend (PFD...

Rapid increase of climate extremes reveals new areas of concern in Amazonia

Abstract Amazonia is highly sensitive to climate extremes, yet we lack an Amazon-wide assessment that examines the spatial-temporal changes in these extreme conditions. We address this within seasons and across the hydrological year, using a quantiles approach that integrates the...

The Python simulations of chemistry framework: 10 years of an open-source quantum chemistry project

Over the past decade, the Python-based Simulations of Chemistry Framework (PySCF) has developed into a widely used open-source platform for electronic-structure theory and quantum chemical method development. This article reviews the major advances since the previous overview in...

Why Metrics Matter in Thyroid Eye Disease

Importance Advances in the understanding of the pathophysiology of thyroid eye disease (TED) provide an opportunity to use novel, targeted therapeutic agents. However, our capacity to assess the efficacy and indications for the new agents is potentially limited by the clinical me...

Prepregnancy Diet Quality Index and Adverse Pregnancy Outcomes

This cohort study of US births examines the association of preconception diet quality with adverse pregnancy outcomes.

Enhanced infrared-to-visible upconversion imaging via metasurface–lanthanide nanoparticle hybrid screens

Abstract Accessing the rich information carried by infrared light typically relies on bulky, complex optoelectronic systems. Lanthanide-based upconverting nanoparticles (UCNPs) offer a compelling alternative by converting infrared light into visible photons through nonlinear anti...

Management of Acute Periodontal Conditions—The EFP S2k Level Clinical Practice Guideline

BACKGROUND: The European Federation of Periodontology (EFP) has developed Clinical Practice Guidelines (CPGs) for the treatment of periodontitis and for the management of peri-implant diseases. In accordance with the 2018 Classification, acute periodontal conditions are character...

Changes in Alcohol Use Among Adults with Cancer Participating in the ECOG-ACRIN EAQ171CD Tobacco Treatment Trial

Abstract Background: Alcohol and tobacco use are known carcinogens. Treating alcohol and tobacco co-use can improve treatment and survivorship outcomes among patients diagnosed with cancer. Methods: We conducted a post hoc analysis of ECOG-ACRIN EAQ171CD trial participants within...