Columbia University

Temporal, Geographic, and Polysubstance Patterns in Orphine Analogue Detections

This cross-sectional study examines the temporal, geographic, and polysubstance patterns in orphine analogue detections.

Psychometric Properties of the French Version of the Provider Co-Management Index-RN

Background Strengthening primary care through team-based models is a global priority as strong primary care systems are consistently associated with improved outcomes. The Provider Co-Management Index for Registered Nurses (PCMI-RN) is a validated instrument measuring co-manageme...

Sensory receptor expansion and neural accommodation in butterfly color vision

The evolution of complex brains required the incorporation of newly evolved neurons into existing circuits, yet the genetic and developmental mechanisms enabling their integration remain poorly understood. Butterflies expanded their color vision by adding a second R7 photorecepto...

Do Children Who Develop Faster Go on to Age Faster in Midlife?

We quantified the association between rate of child development and pace of midlife aging in the Dunedin Study and the Add Health Study. Physical development was quantified in Dunedin participants ( N = 1,037; age 45) using a composite comprised of (1) birth weight for gestationa...

Parental Stigma and “Good Parenting” in Child and Adolescent Mental Health

OBJECTIVE: Parents of children with mental health problems often experience judgment about their parenting. Such stigma is associated with lower parental well-being and greater child symptom severity. Theory-driven descriptions of and interventions for parental stigma are limited...

Exclusion of Participants for Substance Use in Clinical Trials

Patterns of inclusion and exclusion of individuals who use illicit substances from clinical trials have not been well-studied. Given the widespread and increasing prevalence of drug use in the United States, this has significant implications for the generalizability of scientific...

Adsorption energies and decomposition barrier heights for ethylene carbonate on the surface of lithium from cluster-based quantum chemistry

For ethylene carbonate on the (100) surface of lithium, we calculate the adsorption energy in two binding motifs and the barrier height for a ring-opening decomposition reaction. We validate a scheme for producing results in the thermodynamic limit by correcting results obtained...

Universal compactified Jacobians: cohomological invariance and boundary combinatorics

Abstract Pagani and Tommasi have introduced a class of smoothable fine compactified Jacobians $$\overline{\mathcal {J}}_{g,n}^{\,d}(\sigma )\rightarrow \overline{\mathcal {M}}_{g,n}$$ J ¯ g , n d ( σ ) → M ¯ g , n over the moduli space of stable curves, depending nontrivially on...

Cardiovascular and psycho-emotional changes among completers of a medical student cohort with high loss to follow-up

Abstract Background Medical students are exposed to academic and lifestyle factors that may adversely affect cardiovascular and psycho-emotional health. Although these outcomes have been widely studied, most evidence is cross-sectional, and longitudinal evidence from Latin Americ...

Scalable Hydrogen Peroxide Electrosynthesis and Electro-Fenton Pollutant Degradation Using Indium Single-Atom Catalysts

Abstract Electrochemical synthesis of hydrogen peroxide (H2O2) via the two-electron oxygen reduction reaction (2e– ORR) offers a safer, decentralized alternative to the centralized anthraquinone process. However, achieving high current efficiency at industrially relevant current...

Evaluation of a Commercial Pediatric Sepsis Early Detection Alert in the Emergency Department

Importance Screening tools have been implemented with the goal of improving early detection of pediatric sepsis, with limited evidence of effectiveness. The Epic Systems Pediatric Sepsis Early Detection Model (PESM) and its associated clinical alert have been widely implemented i...

Synchronous glacier recession on the southeastern Tibetan Plateau and in Southern Hemisphere mid-latitudes during the last deglaciation: a 10Be moraine chronology from the Hengduan Shan

Establishing precise and accurate chronologies of mountain glacier fluctuations between the polar hemispheres can help test proposed hypotheses for millennial-scale climate changes during the last glaciation and the last glacial termination. Here, we address the relative phasing...

Navigating equity tensions and enacting agency in Chinese TESOL practicums

This qualitative study examined how 38 preservice TESOL teachers placed in Chinese middle schools identified, navigated, and challenged perceived pedagogical inequities during a brief practicum. Using a critical sociocultural framework, reflective papers ( N = 38) and focus group...

Cosmogenic 10 Be as a Tracer for Recent Heliospheric Encounters With Interstellar Cold Clouds and Nearby Supernovae

Abstract Recent works suggest there are periods when the Sun encountered massive interstellar cold clouds which compressed the heliosphere to within Earth's orbit, exposing Earth to interstellar galactic cosmic rays and energetic particles of heliospheric origin. We model 10 Be p...

Scalable, Simple, and Versatile Encapsulation of 2D Materials and Devices

Abstract Air-sensitive 2D materials present fundamental challenges for device integration. Encapsulation is required to preserve intrinsic properties, yet conventional strategies require complicated fabrication workflows and fail with thicker flakes. We demonstrate that electron-...

Improving global rainfall erosivity estimates from IMERG using machine learning–based error correction

Rainfall erosivity is a key driver of soil erosion and hydrologic processes, yet its estimation remains limited by sparse gauge observations and uncertainties in satellite precipitation products. This study presents a machine learning–based framework to improve global rainfall er...

Multilingual Anxiety and the Invention of the Hebrew Native: A Reading of a Hebrew Feuilleton by S. Ben Zion

This article explores the relationship between multilingualism, the attempted revival of Hebrew speech, and the sense of muteness that accompanied Hebrew literary production in the first decade of the twentieth century. It does so through a close reading of a Hebrew feuilleton, w...

Immediate Versus Early Loading Protocols in Rehabilitation of Fully Edentulous Maxilla: A 5‐Year Pilot Randomized Clinical Trial

ABSTRACT Objective To compare 5‐year outcomes of immediate versus early loading protocols for complete implant‐supported fixed dental prostheses in edentulous maxillae. Materials and Methods A prospective randomized controlled trial evaluated 24 patients (144 Bone Level Tapered S...

A phase II pilot trial of an indoleamine 2,3-dioxygenase-1 (IDO1) inhibitor (INCB024360) plus a multipeptide melanoma vaccine (MELITAC 12.1) in patients with advanced melanoma, with sequential evaluation of the tumor microenvironment

Indoleamine 2,3-dioxygenase-1 (IDO1) can mediate immune dysfunction by reducing tryptophan (Trp) and increasing kynurenine (Kyn). The CITN-04 clinical trial (NCT01961115) tested the safety and clinical activity of combination therapy with IDO1 inhibitor epacadostat (INCB024360) p...

Revising the Spin and Kick Connection in Isolated Binary Black Holes

Abstract The origin of black hole (BH) spins remains one of the least understood aspects of BHs. Despite many uncertainties, it is commonly assumed that if BHs originated from isolated massive star binaries, their spins should be aligned with the orbital angular momentum of the b...