Research works

ON CONTROLLED FRACTIONAL VARIATIONAL INEQUALITIES INVOLVING CONVEX FUNCTIONALS

Abstract This paper explores weak sharp solutions for a controlled variational inequality governed by a convex fractional curvilinear integral functional with path-independent properties. The fractional framework involves derivatives or integrals of non-integer order, which intro...

Folic acid–loaded amino-functionalized MCM-41 as a drug delivery system for cervical cancer modulating apoptotic and survival signals

Abstract Cervical cancer remains one of the most prevalent gynecological malignancies worldwide, with high mortality rates particularly in developing countries, necessitating the development of effective and targeted therapeutic strategies. In this study, a folic acid (FA)-loaded...

Extinction-restraint intervention eradicates fear memory encoded in BLA engram cells via D2 receptor-mediated dopaminergic modulation from locus coeruleus

Abstract Despite undergoing exposure therapy, individuals with post-traumatic stress disorder (PTSD) frequently experience relapses when confronted with trauma reminders. This study examined the impact of extinction-restraint intervention (Ext-Res) in a PTSD-related fear relapse...

LLM-based support for digital knitting machine training

Purpose This study investigates how a large language model (LLM)-based chatbot can support novices in machine knitting, a domain that blends creative design, technical operation and digital programming. The research examines whether an LLM assistant can aid undergraduate fashion...

ReVita: home-based transcutaneous auricular vagus nerve stimulation for reducing pathological fatigue in chronic neurological and post-infectious conditions—study protocol for a randomized, double-blind, sham-controlled trial

Abstract Background Pathological fatigue is one of the most prevalent and disabling symptoms across chronic neurological, post-infectious, and inflammatory diseases, yet effective treatments remain limited. Transcutaneous auricular vagus nerve stimulation (taVNS) is a safe, non-i...

Economy Without Oikonomia Semantic Capture and the Disciplinary Naturalization of a Wartime Ledger

The modern word "economy" is treated as a natural category. This paper argues that it is acaptured name. Pre-modern European lexicons maintained at least four lexically distinctregisters for what the word now covers: order-management (oikonomia), money-making(chrematistike), live...

Prioritizing the critical enablers of Quality 4.0 implementation in automotive manufacturing industry: implications for industrial managers and policy-makers

Purpose This study aims to explore and prioritize the critical enablers (CEs) for the successful deployment of Quality 4.0 (Q4.0) in automotive manufacturing industry. Design/methodology/approach Initially, comprehensive literature review related to Q4.0 adoption in manufacturing...

Mechanistic Insights into Enhanced Combustion of aGAP-Coated Boron Nanoparticle

Abstract Boron nanoparticles hold great potential for applications in high-energy fuels, but their practical use suffers from limited combustion performance. Glycidyl azide polymer (GAP) is a promising coating material for boron that can improve its ignition and combustion charac...

Integrative taxonomy reveals multiple Mediterranean invasions by Indo-Pacific Dorvillea (Annelida, Dorvilleidae)

Abstract Biological invasions are a major driver of global biodiversity loss, with the Mediterranean Sea among the most heavily invaded marine regions. However, identification and monitoring of Non-Indigenous Species (NIS) are hindered by taxonomic uncertainty and cryptic diversi...

Mechanism Analysis and Prevention of Road Damage in High-Latitude Permafrost Regions

Abstract Frost heave and thaw settlement occur widely in northern China. Environmental change has increased their occurrence. High-latitude permafrost regions have high temperature sensitivity, experience freeze–thaw settlement, and exhibit unique rheological properties. Multiple...

Community-Led Operationalization of a Champion Implementation Strategy for Anal Cancer Prevention in Nigeria

Abstract Context-specific adaptation of implementation strategies is an important component of promoting evidence-based intervention use. But guidance on systematic approaches is limited. Here we described our mixed method approach to adapting (Study 1) and monitoring (Study 2) a...

Cost of quality management in the agrifood sector: a systematic review of indicators and implementation outcomes

Purpose This study systematically reviews empirical research on cost of quality (CoQ) management in the agrifood sector, where CoQ-related research remains fragmented and under-theorized. It synthesizes evidence on CoQ measurement indicators and the organizational outcomes of CoQ...

Spatial distribution of soil macronutrients and nutrient index for sustainable agriculture in the Khulna region of Bangladesh

Abstract Purpose Evaluation of soil fertility is essential for sustainable agriculture; yet studies on nutrient distribution indices, particularly in Bangladesh, remain limited despite increasing research. The purpose of this study is to identify nutrient indices and create spati...

Operator Engine 2.0.13: Blueprint of a Deterministic Structural Solver

Operator Engine is a deterministic structural solver: it takes aproblem stated in natural language, represents it as planes undertension, classifies the form of the conflict, builds the architecturethat form requires, computes its structural energy, and transforms thestate until...

Fracture laterality as an independent prognostic factor for clinical outcomes after hip fracture surgery

Aims Fracture laterality is routinely recorded in large hip fracture registries for administrative purposes, yet rarely evaluated as a prognostic variable. We aimed to test whether laterality is independently associated with short-term outcomes after hip fracture surgery. Methods...

Colorism, Descriptive Representation, and the Representation of African Americans in the United States House of Representatives

Previous research overlooks how certain ascribed characteristics, such as skin tone, correlate with the representation of marginalized groups. Yet research also demonstrates how colorism shapes candidate evaluations and life experiences. We theorize that colorism, the systemic pr...

Robustness of Regionally Derived, Short-Duration Rainfall Depth-Duration-Frequency Estimates to the Choice of Minimum Interevent Time: Evidence across Climates, Rain Gauge Densities, and Regionalization Approaches

Abstract The choice of minimum interevent time (MIT)—a criterion used to discern independent events from a continuous rainfall record—can affect the resulting partial duration series (PDS) and depth-duration-frequency values (DDFs). However, the mechanisms by which MIT choice aff...

Robust topology optimization with non-Gaussian material fields using polygonal finite elements

Abstract We present a computational framework for robust topology optimization that integrates polygonal finite-element discretizations, spatially correlated non-Gaussian material modeling, and non-intrusive polynomial-chaos surrogates. Spatial uncertainty in Young’s modulus is r...

Advancing Parkinson’s detection from MRI: a deep learning comparison of classical and quantum architectures

Abstract Purpose The precise diagnosis of Parkinson’s Disease (PD) continues to pose a considerable barrier in clinical neurology. This work investigates the capability of sophisticated deep learning architectures to improve Parkinson’s disease identification via Magnetic Resonan...

Recent advances in etiology and treatment of von Hippel-Lindau Disease (VHLD)

Abstract Von Hippel-Lindau disease (VHLD) is a rare autosomal dominant disease, occuring in ~ 1 in 35,000 individuals. Overall, individuals with inherited mutations in the VHL tumor suppressor gene are predisposed to a variety of cancer, including high frequencies of clear cell r...