Research works

Investigation of the long-term effects of conservation tillage systems on the quality of clay-loamy soil in the Eastern Slovak Lowland

Abstract Understanding the factors influencing soil quality is essential for implementing sustainable management practices that ensure long-term agricultural productivity and ecosystem resilience. The four-crop rotation was established in 2005 at the experimental station of the A...

Evaluation of the new Egyptian undergraduate medical program from the perspectives of faculty and institutional leadership: a nationwide, mixed-method study

Abstract Background In response to global calls for medical education reform, Egypt restructured its national undergraduate medical education program from a 6 + 1 model to a competency-based “5 + 2” model. This reformed program emphasizes early clinical exposure, integration of b...

Dual-Mode Responsive Dynamic Afterglow Color in CarbonDots and Carbon Nitride Composite for Advanced Optical Informationand Temperature Sensors

Abstract Responsive dynamic afterglow carbon dot (CD) materials, which can continuously emit light of dynamically varying color after excitation cessation, promise broad applications in advanced information encryption and related fields. However, as most reported CD-based aftergl...

Management of Incidentally Discovered Appendiceal Malignancies: When to Perform Right Hemicolectomy – Case Series and Literature Review

AIM: Appendiceal neoplasms are rare and are most frequently diagnosed incidentally after appendectomy for suspected acute appendicitis. Their optimal management, particularly the indication for completion right hemicolectomy, remains debated due to the absence of standardized gui...

Comparison of Labetalol With Versus Without Magnesium Sulfate on Intraoperative Blood Pressure Variability During Cesarean Delivery in Hypertensive Disorders of Pregnancy: A Retrospective Cohort Study

AIM: This study aims to investigate the effects of two medication regimens—labetalol combined with magnesium sulfate versus labetalol alone—on intraoperative blood pressure variability (BPV) and maternal-neonatal outcomes in patients with hypertensive disorders of pregnancy (HDP)...

Intelligence vs execution: decoupling AI and automation's divergent roles in Ghana's post-COVID economic recovery

Purpose This study decouples artificial intelligence (AI) from automation to examine their distinct yet interrelated roles in stabilizing Ghana's healthcare, manufacturing and banking and finance sectors following COVID-19. Rather than treating the two concepts interchangeably, t...

Research on the image of China's public cultural service institutions on new tourism social media

Purpose This study aims to explore users' perceptions, emotions and social network relationships, as well as the differences among them, regarding the image of major public cultural institutions (museums, libraries and galleries) in mainland China. The findings provide essential...

Research on high-speed train wheelset bearing fault diagnosis based on IDBA-CNN

Abstract To address the challenges in high-speed train wheelset bearing fault diagnosis, including difficulties in optimizing Convolutional Neural Network (CNN) hyperparameters and the tendency of traditional metaheuristic algorithms to get trapped in local optima with imbalanced...

A Pull-Apart Strategyfor Synthetic Rifamycins

Abstract A practical synthetic strategy for the preparation of rifamycin analogues has been developed, enabling access to the first compound modified at the critical enol ether–ketal linkage with demonstrated antimicrobial activity. Leveraging a deconstruction strategy, the rifam...

Comparison of Staged and Concomitant Percutaneous Coronary Intervention in Patients Undergoing Transcatheter Aortic Valve Replacement: A Retrospective Cohort Study

AIM: This study aims to compare the clinical outcomes of concomitant versus staged percutaneous coronary intervention (PCI) in patients with severe aortic valve disease and significant coronary artery stenosis undergoing transcatheter aortic valve replacement (TAVR).METHODS: We r...

Emergent Architectural Drawing Literacy in General-Purpose GPT Systems: A Longitudinal Case Study from Recognition to BIM Execution

Architectural drawings require more than optical character recognition or object detection: useful interpretation depends on integrating geometry, dimensions, graphical conventions, spatial relations, functional semantics, and discipline-specific knowledge. This preprint presents...

BioTwin-PE: An Uncertainty-Aware Multimodal State-Space Framework and Validation Protocol for Longitudinal Placental Monitoring

Placental assessment is necessarily intermittent, while ma- ternal and fetal physiology evolve continuously. This mis- match limits the ability of conventional visit-level prediction models to represent changes occurring between examinations. We present BioTwin-PE, a methods fram...

BeyondElectrochemistry: Tailoring Mechanical Propertiesof Halogen-Substituted Argyrodites for Conformal Dry Coating and EnhancedBattery Performance

Abstract Dry coating of solid electrolytes (SEs) onto cathode materials is a promising strategy for promoting homogeneous interfacial reactions in all-solid-state batteries (ASSBs). While electrochemical properties are considered a key criterion, the coating process fundamentally...

In vitro evaluation of vancomycin-loaded Marlex mesh against staphylococci isolated from periprosthetic joint infection

Aims Extensor mechanism disruption is a major complication following total knee arthroplasty, with treatment often consisting of extensor mechanism reconstruction utilizing monofilament polypropylene mesh (Marlex mesh, C. R. Bard, Inc). Infection following this procedure is devas...

Deposit insurance and bank risk-taking: the moderating role of Islamic banking in the MENA region

Purpose This study investigates the impact of deposit insurance on bank risk-taking and examines how Islamic banking architectures moderate this relationship in the MENA region's dual banking system. Design/methodology/approach We apply panel quantile regressions to an unbalanced...

Synergistic Effectsof Particle Size and MolecularWeight on Chain Entanglements in Single-Polymer Nanoparticles

Abstract The polymer dynamics at the nanoscale exhibit significant deviations from their bulk materials, affecting both our fundamental understanding and practical applications of polymers. Despite growing applications and synthesis advancements of 3-dimensional confined polymeri...

Piezo1–Src signaling rapidly disrupts brain endothelial barrier integrity

Abstract Background Blood-brain barrier integrity is essential for central nervous system homeostasis, yet the mechanisms underlying ultra-acute barrier dysfunction after abrupt hemodynamic changes remain incompletely understood. Piezo1 is a mechanosensitive Ca²⁺ channel expresse...

Targeting PRMT5 alleviates diabetic cardiomyopathy: mechanisms involve Ndufs2 R118 dimethylation-mediated complex I protection and serum PRMT5 as a biomarker

Abstract Background Diabetic cardiomyopathy (DCM) is defined by progressive cardiac dysfunction driven by myocardial ATP depletion, where mitochondrial electron transport chain (ETC) Complex I dysfunction acts as a critical factor. Protein arginine methyltransferase 5 (PRMT5) mai...

Two-wave modified cardiometabolic index change patterns and incident edentulism in Chinese adults: a longitudinal study from CHARLS

Abstract Objectives Complete tooth loss is a late-stage oral health endpoint that may reflect cumulative oral, systemic, behavioral, and social risk processes. We examined whether two-wave patterns of the modified cardiometabolic index (MCMI) from 2011 to 2015 were associated wit...

Perceptions of death, grief and loss in adolescents experiencing non-terminal maternal cancer: a secondary qualitative data analysis

Purpose A diagnosis of parental cancer, even if not terminal, can have a significant and adverse impact on adolescents' lives marked by significant non-death related loss. Research identified that adolescents experiencing parental cancer terminal and non-terminal both exhibited s...