Research works

Investor fears and cryptocurrency price crash risk

Purpose The study investigates the effect of investor fear on cryptocurrency crash risk, with emphasis on overall market sentiment and COVID-19-related fear. It also evaluates the relative performance of Google search-based measures compared to the economic policy uncertainty (EP...

Influence of Isokinetic Muscle Strength Training Combined With Early Functional Exercise on Joint Function After Knee Cruciate Ligament Reconstruction

AIM: The purpose of this study was to evaluate and analyze the influence of isokinetic muscle strength training combined with early functional exercise on joint function after knee cruciate ligament reconstruction.METHODS: A total of 294 patients undergoing knee cruciate ligament...

Clinical applicability of cystatin C-based renal function assessment and HPLC-based therapeutic drug monitoring for predicting cefepime overexposure

Abstract Background Cefepime (CFPM)-associated neurotoxicity is linked to elevated plasma concentrations, particularly in patients with impaired renal function. Although cystatin C-based estimated glomerular filtration rate (eGFRcys) has been proposed as a potentially superior ma...

Nitrogen-Incorporated Reduced Graphene Oxides as ElectrodeMaterials for Tunable Electrochemical Applications

Abstract Because of high defect density and good electrical conductance, nitrogen-incorporated reduced graphene oxides (NrGOs) are highly promising materials for energy storage, energy conversion, and electrochemical applications. Surface area modifications and controllable elect...

Operator Engine 2.0.13: Blueprint of a Deterministic Structural Solver

Operator Engine is a deterministic structural solver: it takes aproblem stated in natural language, represents it as planes undertension, classifies the form of the conflict, builds the architecturethat form requires, computes its structural energy, and transforms thestate until...

Predicting the Unwelcome Return: Insights From a Cohort of Postoperative Haemorrhoid Patients

AIM: Recurrence after haemorrhoid surgery is a clinical concern, but the factors associated with recurrence have not yet been fully elucidated. In particular, the effects of external haemorrhoids and postoperative complications on long-term outcomes have not been clearly defined....

Impact of Early Surgical Debridement on Outcomes in ICU Patients With Sepsis-Associated Intra-Abdominal Infection: A Retrospective Analysis

AIM: To investigate the impact of early surgical debridement, defined as a diagnosis-to-knife time (D-to-K time) ≤12 hours, on intensive care unit (ICU) outcomes in patients with sepsis-associated intra-abdominal infection.METHODS: This single-center retrospective cohort study co...

High-Spatial-ResolutionNear-Infrared ThermographyUsing an Uncooled Silicon-Based Camera

Abstract The demand for noncontact temperature measurements is growing as the microelectronic features to be probed become progressively smaller. However, traditional thermal imaging with infrared cameras is fundamentally constrained by the micron-long wavelength of thermal emiss...

FHAT Technical Note #007B: Prospective Secondary-Window Structural Analog Addendum — Reduced-Amplitude August 7 Analog, PPI Resistance-Field Risk, and 137/134 Support Architecture for SOXL on August 13, 2026

This prospective addendum freezes the August 13, 2026 Secondary-Window scenarios for the Direxion Daily Semiconductor Bull 3X Shares (SOXL) after the August 12 close and before the 08:30 EDT release of the July Producer Price Index. The preferred structural analog is a reduced-am...

Endoscopic mucosal resection for pediatric endoscopists: technical principles, practical considerations, and lessons from adult practice (with video)

Abstract Purpose Pediatric endoscopic mucosal resection (EMR) remains uncommon outside specialized centers, and pediatric-specific educational resources and procedural training opportunities are limited. This video-based educational article demonstrates core EMR principles while...

Genome-wide identification and comprehensive characterization of the Aux/IAA gene family in Cucurbita moschata and its responses analysis to abiotic stresses

Abstract Background Auxin is a central phytohormone involved in regulating plant growth, development, and stress responses, with the Aux/IAA gene family functioning as an essential component of the auxin signaling pathway. To elucidate the genomic features and potential functions...

Unveiling Systemic Barriers to High-Grade Glioma Management in Non-Tertiary Centers: A Case Report and Analysis of Resource-Limited Care Challenges

AIM: High-grade gliomas (HGGs) are among the most aggressive brain tumors, including gliosarcoma. This report aims to present a case of gliosarcoma managed in a general non-tertiary hospital and to highlight the systemic barriers that delayed diagnosis and treatment.CASE PRESENTA...

Beyond the Black Box: From Open Hardware to Open Validation in Analytical Science

Open scientific hardware has lowered barriers to the construction, adaptation, and local deployment of analytical instruments. Yet openness of the instrument alone does not make the resulting analytical evidence reproducible or independently assessable. Calibration models, raw da...

Zulfia Estimation Theory (ZET): (f (x|θ) is imposed in 1922. Generated in 2026)

AbstractSince Fisher introduced Maximum Likelihood Estimation in 1922, statisticalinference has imposed a distributional assumption f (x|θ) before examining a singleobservation. For 104 years this imposition has been treated as necessary. It is not.This paper introduces Zulfia Es...

Influencing Factors of Air Bubble-Induced Pressure Difference in Drainage Tubes: An In Vitro Study

AIM: This study evaluated the effect of the presence of air bubbles in a drainage tube on its pressure difference and analyzed the relationship between air bubble volume, tube diameter, drainage fluid viscosity, and pressure difference. Accordingly, it provides a theoretical basi...

N,S,P-Modified CarbonDot Nanoadditives for High-LoadAntiwear Protection for Steel-to-Steel Contact

Abstract Carbon dots are attractive lubricant nanoadditives because their nanoscale size and tunable surface chemistry allow them to interact with confined friction interfaces. However, achieving effective antiwear protection under high contact loads requires surface structures t...

Age-related effects of comprehensive in-patient physiotherapy after lung cancer surgery across age groups: an ambispective observational cohort study in middle-aged and older patients

Abstract Background Postoperative recovery after lung cancer surgery may be influenced by age, comorbidity burden, and perioperative rehabilitation strategies. However, evidence regarding the age-related effects of structured early inpatient physiotherapy programs remains limited...

Beyond the Black Box: From Open Hardware to Open Validation in Analytical Science

Open scientific hardware has lowered barriers to the construction, adaptation, and local deployment of analytical instruments. Yet openness of the instrument alone does not make the resulting analytical evidence reproducible or independently assessable. Calibration models, raw da...

Antibody repertoire sequencing of SARS-CoV-2-immunized wildtype, V(D)J-humanized and IGHV3-53 knock-in mice

This project contains sequencing datasets generated to characterize antibody repertoire responses in SARS-CoV-2-immunized mouse models. The dataset includes 10x Genomics single-cell V(D)J sequencing of antigen-specific memory B cells isolated from V(D)J-humanized and wild-type mi...

Spontaneous ChlorineGeneration via Interfacial Oxidationof Chloride by O2 on Acidic Microdroplets

Abstract Reactive chlorine species significantly influence atmospheric chemistry, yet their sources remain inadequately defined. We have discovered a spontaneous formation pathway for substantial molecular chlorine (Cl2) from the oxidation of chloride (Cl–) through interfacial ox...