Wuhan University

PGMMF-Net: a POI-Guided Multi-modal Mamba Fusion Network for urban impervious surface extraction from optical and SAR imagery

Accurate extraction of urban impervious surfaces (IS) is essential for urban environmental analysis. However, optical-based methods are affected by shadows and spectral confusion, while optical-SAR fusion lacks urban functional semantics. Point-of-interest (POI) data provide comp...

Toeplitz-structured deep unfolding network for TomoSAR 3-D reconstruction

Urban area 3-D imaging is a key application of synthetic aperture radar (SAR). Classical compressive sensing-based tomographic SAR methods rely on iterative optimization, which is computationally expensive and sensitive to hyperparameter tuning, limiting its scalability for large...

Early-life exposure to polypropylene microplastics and DEHP induces ASD-relevant neurodevelopmental alterations involving mTOR-regulated autophagy impairment

The health risks of polypropylene plastic, a major food-grade polymer, are often underestimated. Current evidence indicates that infants and young children may ingest millions of polypropylene microplastic particles (PP-MPs) daily, accompanied by co-exposure to di(2-ethylhexyl) p...

Observation-based analysis of horizontally oriented ice crystals using dual-angle polarization lidar and cloud Doppler radar in Beijing

Abstract. Ice crystal orientation strongly influences cloud radiative properties and remote sensing retrievals, but long-term, high-resolution quantitative observations remain scarce. This study presents comprehensive case studies and statistical analyses of horizontally oriented...

CACA guidelines for the management of adult cancer pain

Abstract Cancer pain, one of the most prevalent and distressing symptoms in cancer patients, is closely associated with cancer diagnosis, therapeutic interventions, quality of life, and survival outcomes. Effective cancer pain management requires multidisciplinary collaborative a...

Aggregation-Induced Emission: Illuminating the Path from Photothermal Ablation to Systemic Immunity

Abstract Cancer photothermal immunotherapy has attracted great attention in cancer treatment for its ability to trigger systemic antitumor immune responses and reverse tumor immune tolerance, offering prospects for clinical application. However, conventional photothermal agents s...

MC-OIWQR: Multimodal Contrastive Learning for Optically Inactive Water Quality Retrieval

Retrieving optically inactive nutrients from satellite observations remains challenging because TN, TP, and NH3-N are only indirectly linked to water reflectance and may respond to different environmental contexts. Here, we propose MC-OIWQR, a multimodal framework that combines s...

Quantifying the fiscal benefits of obesity prevalence reduction in China

With obesity becoming increasingly prevalent in China, its impact extends beyond health losses to wider public finance pressures. This study assessed the fiscal implications of reducing obesity prevalence from the government perspective and explored the potential fiscal benefits...

Decreased cerebrospinal fluid NDRG2 is associated with non-Alzheimer's disease derived mild cognitive impairment

Background Mild cognitive impairment (MCI) lacks clear clinical biomarkers. N-Myc downstream-regulated gene 2 (NDRG2) is predominantly localized in astrocytes and is implicated in cognitive function. Objective This study aims to explore whether cerebrospinal fluid (CSF) NDRG2 cou...

Nanopore‐Based Multiparametric Single‐Molecule Protein Detection: From Structural Analysis to Clinical Translation

ABSTRACT Single‐molecule protein analysis is crucial for elucidating biological processes and enabling early disease diagnosis. Nanopore sensing technology, owing to its label‐free operation, high throughput, and direct electrical readout, has emerged as a highly promising platfo...

Inadequate Reporting of Harms in RCTs of Chinese Herbal Medicine Formulas: A Systematic Survey of Leading Medical Journals

ABSTRACT Objective To evaluate harms reporting practices in placebo‐controlled randomized clinical trials (RCTs) of Chinese herbal medicine (CHM) formulas published in Quartile 1 (Q1) English‐language and Tier‐1 Chinese journals. Methods This systematic survey evaluated harms rep...

Numerical simulation on full-link underwater LIDAR with an optical filter using OAM modulation

Optical filtering based on orbital angular momentum (OAM) modulation can effectively suppress background noise and multiple-scattering light in water, thereby improving the signal-to-noise ratio (SNR) of underwater lidar. Although OAM modulation has been investigated in previous...

Where to Restore:Hydrological Connectivity DifferentiatesEcological Restoration Outcomes in Dam-Regulated Rivers

Abstract Ecological stabilization of sandbars is essential for maintaining habitat integrity in dam-regulated rivers, yet whether restoration effectiveness varies systematically within project areas and is predictable from design-phase hydrological data remains largely unexamined...

Cavity Confinement to Create Multi‐Dimensional Functional Partition Iron Sites Synergistically Promotes Multi‐Scenario Ammonia Synthesis

ABSTRACT Electrocatalytic ammonia synthesis centered on nitrate reduction constitutes a vital component of the future green synthesis pathway from nitrogen to nitrogen oxides to ammonia. However, catalyst development often overlooks the critical coordination between the intricate...

TIR-VD: Binary vulnerability detection based on texture and input-related embeddings

The rapid expansion of IoT systems fuels the reuse of vulnerable code in firmware binaries, exposing IoT devices to network attacks. Current dynamic analysis, which relies on emulation and fuzzing, suffers from high latency, hindering large-scale vulnerability detection that is e...

Innovative abdominoperineal surgery for fertility-preserving cervicovaginal reconstruction in five patients with the rare condition of congenital cervical malformation coexisting with vaginal atresia

Congenital cervical malformation coexisting with vaginal atresia is a rare but challenging anomaly that obstructs menstrual outflow and threatens future fertility. This study aimed to describe a fertility-preserving laparoscopic abdominoperineal cervicovaginal reconstruction tech...

Neutrophil heterogeneity and crosstalk with cerebral-resident cells: therapeutic targets for ischemic stroke

Acute ischemic stroke elicits a robust inflammatory response within the brain. As one of the first peripheral immune cells to infiltrate the ischemic parenchyma, neutrophils show high heterogeneity and engage in complex crosstalk with resident brain cells. In this review, we firs...

A Bibliometric Analysis of Global Research Trends on Companion Animals and Mental Health: Revealing Research Hotspots and Future Prospects

Companion animals have increasingly become central to human emotional life, yet the literature linking living with companion animals, human–animal interaction, and mental health remains fragmented. This study mapped global research trends on companion animals and mental health fr...

Numerical Assessment of Seismic Performance of a Lead-Rubber Base-Isolated RC Frame under Site-Specific Earthquake Excitations: A Case Study of Quetta, Pakistan

Quetta lies in one of Pakistan's most seismically active regions, where the Building Code of Pakistan (BCP-2007) assigns a design ground acceleration of 0.32 g and UBC-97 Seismic Zone 4 is adopted as the design basis. Despite this hazard, location-specific research on sei...

Hepatocyte OTUD1 promotes hepatic stellate cell activation and liver fibrosis by stabilizing HSP90β

Crosstalk between parenchymal and nonparenchymal cells of the liver mediates the activation of hepatic stellate cells (HSCs). Activated HSCs transform into myofibroblasts and produce the extracellular matrix (ECM), and massive ECM accumulation can affect liver function and eventu...