University of California, Los Angeles

Identifying the proton donor in electrocatalytic hydrogen evolution by a model hydrogenase

Abstract Proton transfer is essential in all multi-electron transformations. Identifying the proton donor in such processes is crucial to understanding the catalytic mechanism and optimizing activity through pK a matching, which can enhance proton transfer rates. However, aqueous...

Early sleep and sensory over-responsivity relate to insular functional connectivity with sensorimotor cortices and cerebellum in infants at varying likelihood for autism

Abstract Sleep problems and sensory over-responsivity (SOR) are common, co-occurring, and early emerging features of Autism Spectrum Disorder (ASD). Yet, the early neural mechanisms underlying these symptoms remain unclear. Here, we used resting-state fMRI data from the Infant Br...

The Digital Mental Health Study assessed feasibility of large-scale digital sensing for depression and anxiety

Abstract Data passively obtained from smartphones and wearables can provide nearly continuous objective information that enables quantification of states and traits across broad physiological, behavioral, and emotional domains impacted in mental health conditions, including depre...

Racial Ambiguity and Religious Vulnerability in Late Nineteenth- to Mid-Twentieth-century Iran: The Life of Ghulam-‘Ali Siyah Khurasani of Yazd, an Afro-Iranian Baha’i

Scholars of Iranian history have begun turning their attention to the presence of enslaved Africans in Iran. The history of Africans and racial categories and identities has emerged in academic literature as a topic worthy of study. 1 While there is much yet to be learned, we can...

Logging Activities for August, 03th, 2026 – [Mcgill University]

We are grateful for being in Mcgill University, today, August 03th, 2026. It is very crowdly and many people in groups are vis-iting Mclennan library. We save some notes here about our online activities and researches. We are wondering if a technology canstudy the influence diagr...

Understanding temporal changes in intrinsic capacity: analysis of domain-specific intrinsic capacity using SHARE data

Global population aging challenges acute, disease-centric healthcare models and highlights the need for functional markers of aging. The World Health Organization's intrinsic capacity (IC) framework, encompassing cognition, vitality, locomotion, psychological well-being, and sens...

Feeling the Best Fit: The Role of Emotions in College Decisions

Using ethnographic observations and interviews with students and staff in a college access nonprofit (CAN), I show that college-going inequalities may also reflect structurally based emotional barriers and that these barriers can be overcome through opportunities to imagine futur...

Divergent concerted and stepwise cycloadditions via enantioselective cross-conjugated iminium-ion catalysis

Cycloadditions are described as either concerted or stepwise processes, where a catalyst can influence both the mechanism and the peri-, regio- and stereoselectivity. We report experimental and DFT-computational investigations that reveal the versatile reactivities of cross-conju...

Sexual and gender minority youth experience serious mental health risks, yet are not impacted by typically efficacious interventions: secondary mental health outcomes from randomized controlled trial ( ATN 149)

Background Sexual and gender minority youth (SGMY) often experience discrimination and stigma related to their sexual orientation or gender identity. This increases their vulnerability to HIV, poor mental health outcomes, including suicide, and low uptake of HIV prevention throug...

Pharmaceutical Pricing and R&D as a Global Public Good.

This paper examines the international variation in the prices of branded pharmaceuticals. We consider short-run profits, or quasi-rents, as representing each country's contribution toward the global public good of therapeutic information embodied in new pharmaceuticals. We charac...

Outcomes of a Novel Full-Service, Free Ophthalmology Clinic-Within-A-Clinic: A Four-Year Longitudinal Study.

PURPOSE: We evaluate the Clínica Esperanza Ophthalmology Service, a free service for uninsured patients in southern New England. METHODS: The service operates monthly under a novel clinic-within-a-clinic model, existing as a subsidiary of a local free clinic. A mixed-methods prog...

Effects of early adulthood chronic sleep disruption on late life cognition, brain pathology, and microglial reactivity in the PS19 mouse model of tauopathy

Abstract A bidirectional relationship has been proposed between sleep and Alzheimer’s disease pathology, such that disruption to sleep can lead to increases in the expression of tau or its phosphorylation. Over the long term, this can potentially lead to greater expression of neu...

Independence Day: A Poetry to Liberation In Memory of Benin Independence

We would like to express few words of Gratitude to Benin, as August 1th, 2026, is their symbolic Independence day. We support this Poetry with some online quotes, and other notes.

Spatial heterogeneity in the distance-decay pattern of migration: facts and explanation from intercity migration network in China

Although internal migration is increasing rapidly in many developing countries, such as China, little is known about its spatial patterns beyond the general tendency of distance decay. A detailed understanding of the spatial patterns of internal migration is beneficial for addres...

SkipOPU: An FPGA-based Overlay Processor for Large Language Models with Dynamically Allocated Computation

Large language models (LLMs), particularly decoder-only models with auto-regressive decoding, have achieved remarkable performance across a wide range of tasks, but their inference efficiency remains a critical bottleneck due to rapidly growing parameters and memory-bound generat...

Quantitative Evaluation of Geographic Atrophy Progression Using Geographic Atrophy Lesion Front Displacement

Purpose: To evaluate the temporal behavior and relative variability of a margin-based metric, lesion front displacement, for quantifying geographic atrophy (GA) progression secondary to age-related macular degeneration and to compare its performance with conventional metrics. Met...