University of California, Los Angeles

RobustCell: a model attack-defense framework for robust transcriptomic data analysis

Abstract Computational methods should be accurate and robust for tasks in biology and medicine, especially when facing different types of attacks, defined as perturbations of benign data that can cause a significant drop in method performance. Therefore, there is a need for robus...

Building a Stack for Systems Deployment

We are introducing few lines of methodology to start building Models & Systems for Deployment. We start first with Asana Platform and the Automated Fact-Checker [here]. More Collaboration Invitation will be sent to participate in the project.

Pixel super-resolved fluorescence lifetime imaging using deep neural networks

Abstract Fluorescence lifetime imaging microscopy (FLIM) is a powerful quantitative technique that provides metabolic and molecular contrast, offering strong translational potential for label-free, real-time diagnostics. However, its clinical adoption remains limited by long pixe...

Sugammadex and postoperative pulmonary complications after upper gastrointestinal endoscopy

Tsai et al. report that sugammadex use was associated with fewer postoperative pulmonary complications than neostigmine following upper gastrointestinal endoscopy [1]. These findings contribute to the growing body of evidence supporting the respiratory benefits of sugammadex comp...

Sucralose Alters Gut Microbiota, Intestinal Metabolites, and Epithelial Serotonergic Responses to Visceral Stimulation in Mice Exposed to Chronic Restraint Stress

Background/Objectives: Dietary modifiers of the gut ecosystem may influence intestinal and host responses associated with psychological stress. However, it remains unclear whether sucralose, a widely consumed non-nutritive sweetener, alters host–microbiota interactions following...

Affidavit of Support [SponsorShip Path]

We are grateful for the Opportunity to apply to Biola University. The platform is requesting an affidavit of Support. In the Internet Guidelines, Some Institutions can offer Affidavit of Support as SponsorShip Investments.

Encapsulation of AAVs into Protein Vault Nanoparticles as a Novel Solution to Gene Therapy’s Neutralizing Antibody Problem

Abstract Although adeno-associated virus (AAV) has enjoyed enormous success as a delivery modality for gene therapy, it suffers from high prevalence of preexisting neutralizing antibodies in human populations, limiting who can receive potentially life-saving treatments. As a nove...

Opioid prescription patterns for hidradenitis suppurativa in the emergency versus ambulatory care settings

Abstract Hidradenitis suppurativa (HS) is associated with significant pain. However, there is a paucity of literature examining opioid prescription patterns in HS in different healthcare settings. We aim to determine differences in opioid prescription patterns between HS patients...

Changes in neurodevelopmental outcomes from 24 to 36 months among children HIV-exposed uninfected (CHEU) and HIV-unexposed (CHU)

Objective: To compare neurodevelopment through 36 months between breastfed children who are HIV-exposed and uninfected (CHEU) exposed to maternal dolutegravir (DTG)-based antiretroviral therapy (ART) and children born to mothers without HIV (CHU). Methods: We enrolled a prospecti...

Probing the jet transport coefficient of cold nuclear matter in electron-ion collisions

Abstract We investigate the transverse momentum broadening~(TMB) of particle production in upcoming electron–ion collision experiments, an important manifestation of jet transport in cold nuclear matter. By considering the effects of parton multiple scattering in nuclear medium w...

Tracking the baryon number with nuclear collisions

Baryon quantum number is found to be conserved since baryogenesis in the early Universe. Conventionally, each fractionally charged valence quark is understood to carry one-third of a baryon number. An alternative hypothesis posits that baryon number is instead carried by a baryon...

Lipids in endothelial-to-mesenchymal transition

Purpose of review Endothelial-to-mesenchymal transition (EndMT) has been implicated in the development of cardiovascular disease, including atherosclerosis. EndMT is a complex continuum with multiple involved pathways, each with different pathophysiologic implications depending o...

A General Approach for Estimating Projective IRT Models

Projective Item Response Theory (PIRT) modeling is a measurement framework in which multidimensional item response models are expressed in terms of lower-dimensional (e.g., unidimensional) proxy IRT models. Existing PIRT methods and their associated estimators currently rely on l...

Quantitative analysis of binocular alignment by Hess screen testing in surgery for superior oblique palsy

Background/Aims: Conventional prism-cover strabismus measurement is compromised by nonstandard and poorly repeatable target locations. We developed a general method to quantify incomitant strabismus in repeatable, defined gazes and illustrate its application to commonly performed...

Quantitative computed tomography improves prediction of survival across ILD subtypes

Background Quantitative computed tomography (CT) methods are recognized as valuable tools for risk stratification in fibrotic interstitial lung disease (ILD). Data-driven textural analysis (DTA) is one such approach that correlates with worse lung function and shorter survival in...

Thermohaline gradients and frontal regimes in the northwestern Tropical Atlantic

Abstract. At the edge of the Amazon River plume, stirring by the North Brazil Current (NBC) and its eddies creates sharp surface thermohaline gradients on scales of O(1–100) km. This study provides a comprehensive picture of these gradients and fronts associated with the region's...

Visual Field Progression Rate and Laminar Depth and Curvature in the African Descent and Glaucoma Evaluation Study (ADAGES)

Abstract P urpose To determine if lamina cribrosa (LC) depth and curvature predict visual field (VF) progression rate in the African Descent and Glaucoma Evaluation Study (ADAGES) cohort in patients with primary open angle glaucoma (POAG). S ubjects Participants, and/or Controls....

Bank Systems

We are introducing the Axiomatization Framework of Bank Systems. Some theorems are completed about Housing, and other Assets Management.

Risk and Protective Factors for Suicidal Ideation and Attempts Among Older Adults in California, 2021–2024 Pooled Cross-Sectional Study

Background/Objectives: Older adults have high rates of suicide, but there is little research on age-specific correlates of suicide. The purpose of this study was to examine risk and protective factors for suicidal ideation and attempts across adult and older adult age groups in a...

Bank Systems

We are introducing the Axiomatization Framework of Bank Systems. Some theorems are completed about Housing, and other Assets Management.