University of California, Los Angeles

Prevalence and risk factors of falls among older adults in the United States: a cross-sectional study

Several studies have examined falls among older adults in the United States; however, studies using recent nationally representative data to evaluate fall prevalence and associated factors in this population are limited. We investigated the current prevalence of falls among older...

Hepatocyte-intrinsic ER stress and NRF2 initiate primary sclerosing cholangitis, providing therapeutic insights

primary sclerosing cholangitis (PSC) is a severe liver disease that can progress to cholangiocarcinoma. Therapeutic development has been hindered by the rarity of PSC and by its poorly understood origin, which reflects incompletely defined genetic and environmental risk factors....

Cancer Screening and Citizenship Status in the US

Importance: Immigrants without US citizenship, or noncitizens, disproportionately endure poverty, labor exclusions, and inadequate health care access-structural drivers of adverse cancer outcomes. While screening is critical for preventing cancer deaths, and cancer is the leading...

Staff Perspectives on Optimising Organisational Responses to Patient‐Initiated Workplace Violence

AIMS: To identify existing and ideal practices for responding to patient-initiated workplace violence in the US Veterans Health Administration. DESIGN: Cross-sectional, descriptive qualitative design. METHODS: Qualitative interviews with staff (n = 31) in eight veteran healthcare...

Volunteering and resilience in wartime: evidence from two population-based studies in Israel

Abstract Background Resilience is a key factor in coping with and recovering from large-scale traumatic events. Although volunteering has generally been associated with improving or maintaining resilience, evidence from wartime contexts is mixed. This study examined the associati...

Building a Stack for Systems Deployment

We are introducing few lines of methodology to start building Models & Systems for Deployment. We start first with Asana Platform and the Automated Fact-Checker [here]. More Collaboration Invitation will be sent to participate in the project.

Chronic oral exposure to didecyldimethylammonium chloride induces region-specific intestinal dysfunction and gut microbiota remodeling in mice

bstract Didecyldimethylammonium chloride (DDAC) is a widely used quaternary ammonium disinfectant, but its effects on intestinal physiology following chronic oral exposure remain poorly understood. Here, we investigated the impact of chronic dietary DDAC exposure on intestinal fu...

Neural mechanisms of sensory over-responsivity in youth with early caregiver-related adversity

Abstract Sensory over-responsivity (SOR) is an impairing sensory processing challenge prevalent across a range of clinical and neurodevelopmental populations, as well as those with experiences of early caregiver-related adversity. Despite its prevalence and impairing nature, litt...

Management of Infantile Epileptic Spasms Syndrome: A survey of US pediatric hospitals

Abstract Objective To evaluate the management practices of Infantile Epileptic Spasms Syndrome (IESS) across tertiary pediatric hospitals in the United States using a survey‐based approach. Methods A 21‐question survey focused on management setting, work‐up, follow‐up and treatme...

Right hippocampal volume and attenuated psychotic symptoms distinguish subgroups of youth with common patterns of temporoparietal effective connectivity

Abstract Associations between patterns of brain connectivity and brain structural features have transdiagnostic relevance to psychopathology. There is considerable evidence for disruptions to the hippocampus and temporoparietal brain systems in psychotic disorders. The present st...

Systematic review on the association between brain-related measures and upper limb movement characteristics after stroke

Abstract Background Upper limb (UL) movements are highly diverse, as are movement deficits following stroke. The relationship that stroke pathology has with UL impairments and their recovery has been studied with an increasingly complex array of neuroimaging and neurophysiology t...

Multicenter retrospective study on perceived effectiveness, reported side effects, and cognitive outcomes of SSRIs in 22q11.2 deletion syndrome

22q11.2 deletion syndrome (22q11DS) markedly increases risk of psychiatric disorders, including anxiety and mood disorders, and is associated with a spectrum of cognitive impairment, from borderline functioning to intellectual disability, with cognitive decline frequently reporte...

Impact of a health education intervention on knowledge, attitudes, and use of visibility materials among commercial motorcycle riders: a quasi-experimental study in Cameroon

Abstract Background Commercial motorcycle riders are among the most vulnerable road users in low- and middle-income countries, with poor visibility contributing significantly to road traffic crashes, particularly under low-light conditions. Visibility materials such as reflective...

Cataloguing & Referencing Art

In this document, we are creating a collection of objects, such as Internet Hyperlinks, Images, Quotes, etc. This activity is coherent with Mathematics Axiomatic Rules: At the beginning, there was an empty set, and the collection of objects create non-empty sets.

Cataloguing & Referencing Art

In this document, we are creating a collection of objects, such as Internet Hyperlinks, Images, Quotes, etc. This activity is coherent with Mathematics Axiomatic Rules: At the beginning, there was an empty set, and the collection of objects create non-empty sets.

Computing Hardware Request for College or University Degree

They are important Computing Minimum Hardware Specifications to enroll and complete a program in the faculty of arts & science [data science, mathematics, and/or Statistics]. We introduce a short guideline [it is possible to submit a hardware request to some institutions and Jour...

Fecal microbiome transplant in food allergy in humans and mice identifies a role for bile acid metabolites in oral tolerance

The gut microbiome has been implicated in the pathogenesis of food allergy (FA), prompting microbiome-focused interventions. We evaluated, in a phase 1 open-label trial (NCT02960074), the safety and efficacy of oral encapsulated fecal microbiome transplantation (FMT) in 15 adults...

Ten years of student-reported outcomes from simulation-based interprofessional education in an underrepresented academic setting

Simulation-based interprofessional education is widely used to foster collaborative competencies among health professions students; however, evidence from underrepresented and minority-serving academic health settings remains limited. We conducted a retrospective program evaluati...

Novel Explantation Protocol for Cardiac Recovery and Device Weaning Post-Left Ventricular Assist Device Therapy: A Single-Center Experience

Although some patients may exhibit significant myocardial improvement after the placement of a durable left ventricular assist device (LVAD), there are no established guidelines on determining patients who may be eligible for explantation. In this single-center case series, three...

A compendium of next-generation patient-derived models for diverse cancers

Abstract The development of new therapeutics and the validation of pathogenetic cancer mechanisms require representative laboratory models 1,2 . However, existing collections represent only a fraction of the diversity observed in human cancer 2–4 . Recent technologies have enable...