University of California, Los Angeles

Contemporary Analysis of the Volume–Outcome Relationship for Patients With Nontraumatic Subarachnoid Hemorrhage

Background Nontraumatic subarachnoid hemorrhage (SAH) carries a substantial mortality burden and risk of long‐term morbidity. Although prior investigations have demonstrated an inverse association between SAH admission volume and in‐hospital mortality, reported thresholds remain...

Testing Group Differences in Nonlinear Growth Curve Modeling with Penalized Spline

Longitudinal data analysis in social and behavioral sciences often assumes a linear change over time, but human behavior is complex and frequently exhibits nonlinear patterns. Regression spline is a popular approach in machine learning to model nonlinear trajectories. While tradi...

Reproductive numbers and traveling fronts in models of protest dynamics with police management

Protests often spread through social networks and across cities, a phenomenon that can be modeled using reaction–diffusion systems. Building on the model in [10] , which links protest activity and social tension, we study an extended model that also includes police protest manage...

Decoupling Stable Cyclic Deformation From Defect Accumulation in Metals

ABSTRACT Fatigue resistance in metals is fundamentally constrained by a long‐standing dilemma: the strain hardening required to suppress deformation localization is typically achieved through the accumulation of dislocations and other defects that ultimately promote fatigue damag...

Cullin-5 RING E3 ligase limits CD8⁺ T-cell persistence and effector responses during chronic antigen stimulation

Abstract T-cell exhaustion limits durable antitumor responses and remains a barrier to adoptive cell therapies (ACT) in solid tumors. To identify regulators of T-cell persistence, we performed genome-wide CRISPR knockout screens in primary human CD8⁺ T cells expressing an NY-ESO-...

A short note on differential equations and on Geometry

A short note on differential equations. We add some lines of interest about Some topics in Geometry.

Short Communication on Email Management Systems

We present the opportunity to Manage Emails with More in-depth Computing Systems. Many options and examples are of interest.

Clinical Outcome Differences in Asia Versus Non-Asia Intracerebral Hemorrhage: IPD Analysis From BP-Lowering Clinical Trials

BACKGROUND: Evidence of regional differences in clinical outcomes after intracerebral hemorrhage (ICH) is still scarce. We quantified differential outcomes and response to early intensive blood pressure lowering treatment by region in the Blood pressure in Acute Stroke Collaborat...

Sexual Orientation and Gender Identity Data and HIV Preexposure Prophylaxis Disparity Detection

Importance US federal reporting changes in 2025 removed sexual orientation and gender identity (SOGI) measures from health-center reporting, raising concerns about equity surveillance. Objective To quantify how incomplete or absent SOGI data are associated with detection of dispa...

Patient-Specific Mirrored Planning Leads to Superior Symmetry for Late Post-Traumatic Deformity After Orbital Zygomatic Maxillary Complex Fractures

Background: Post-traumatic orbital-ZMC deformity is notoriously difficult to correct because of soft tissue contraction and loss of anatomic landmarks. To see whether virtual planning is beneficial, we studied orbital/malar volume correction, globe position, malar projection and...

Association of Neoadjuvant Versus Adjuvant Chemotherapy on Pre-Pectoral Tissue Expander Based Reconstruction Outcomes Following Mastectomy

Background: Prepectoral implant-based reconstruction has reemerged as a preferred technique for breast reconstruction after mastectomy, but introduces risks of prothesis infection. With increasing reliance on neoadjuvant chemotherapy (NACT), which can modulate the immune system a...

Laboratory Measurements of Energy Partitioning and Anomalous Electron Heating in Magnetized, Perpendicular Collisionless Shocks

Abstract We present laboratory results on energy partitioning from supercritical, magnetized collisionless shock experiments ( M A ∼ 8, M ms ∼ 4). We report the first observation of fully developed laboratory shocks that evolve for more than seven upstream ion gyroperiods and hav...

Kynurenine Pathway Activation is Associated with Poor Sleep Efficiency in Men With HIV

Background: Sleep disturbances are common in people with HIV, yet the underlying biological mechanisms remain poorly understood. Chronic immune activation in HIV can induce the tryptophan-kynurenine (TK) pathway, which both reduces melatonin synthesis and increases production of...

Vertical distribution of pollution trapped by wintertime surface inversions in Fairbanks, Alaska, during the ALPACA experiment

Abstract. Air pollution in cold wintertime urban areas is a ubiquitous problem. Surface temperature inversions under low wind conditions and surface emissions lead to the formation of a shallow polluted surface layer (PSL). The presence of this PSL is well documented, but its hei...

Adolescent Worry About Experiencing Firearm Violence and Its Association With Mental Health

OBJECTIVE: To examine the associations between worrying about experiencing firearm violence, past-month psychological distress, and past-year suicide ideation among California adolescents. METHODS: Cross-sectional analysis of a representative California adolescent sample (n = 215...

Heterogeneous beliefs, asset prices, and business cycles

We develop a complete-market production economy in which heterogeneous beliefs about productivity growth affect both asset prices and real activity. Firms must hire workers before productivity is realized, so operating leverage increases the exposure of profits to productivity ri...

THEMIS: spin axis magnetic field reconstruction

Abstract. The Time History of Events and Macroscale Interactions during Substorms (THEMIS) mission investigates the coupling between the solar wind and Earth's magnetosphere using five identical spinning spacecraft. Each spacecraft rotates at a predefined rate to stabilize it and...

Navigating Disrespect in the Classroom: Intersectionality Pedagogy as Humanizing Praxis for Black Women Faculty

This case study examines intersectionality pedagogy (IP) as a humanizing approach to teaching that centers Black women’s voices and experiences in higher education. Through Janice’s experience, the case illustrates how IP disrupts anti-Black, gendered racism and white-cis-hetero-...

Machine Learning‐Based Recurrence and Survival Prediction in a Large Institutional Upper Extremity Soft Tissue Sarcoma Cohort

BACKGROUND AND OBJECTIVES: Upper extremity soft tissue sarcomas (UE STS) present unique management challenges; existing prognostic nomograms were developed from mixed anatomic cohorts. This study develops anatomically specific machine learning (ML) models to predict UE-STS outcom...

The emotion regulation and recognition account of empathy‐related processes in autism: a multimodal, multilevel case–control study

BACKGROUND: Recent evidence suggests that many autistic individuals exhibit heightened emotional responsiveness to others' affect despite greater difficulty recognizing others' emotions and accurately inferring their perspectives. This study introduces and preliminarily evaluates...