University College London

Post-diagnostic support for dementia in the UK: mapping access, delivery and gaps in provision

Abstract Background Dementia is a progressive condition affecting approximately 982,000 people in the UK, with substantial implications for people living with dementia, carers, and healthcare systems. Effective post-diagnostic support is essential for managing symptoms and mainta...

Technological variability in Etruscan amphora production at Vulci: Evidence from petrographic and compositional analysis

This study investigates the production of Etruscan transport amphorae from Vulci (central Italy) through an integrated programme of ceramic petrography and bulk compositional analysis (ICP-MS). A total of 48 amphora samples, collected during two sampling campaigns (2021 and 2023)...

Stigma, discrimination-related events, and determinants among adult people living with systemic lupus erythematosus (SLE): Systematic review and indicator-level meta-analysis

BackgroundSystemic lupus erythematosus (SLE) is a complex autoimmune disease with 0.4 million new cases diagnosed annually. With its wide variety of visible and invisible manifestations, people living with SLE report being exposed to stigmatization, which impacts their personal a...

Pho84/GLUT2 are cellular myo-inositol exporters regulated by inositol pyrophosphates

Abstract Inositol is an essential nutrient for most living organisms, as combinatorial phosphorylation on this cyclic sugar generates key cellular messengers, such as lipid-bound phosphoinositides (PtdInsPs), water-soluble inositol phosphates (InsPs), and high-energy inositol pyr...

Improved building performance prediction model based on the OODA-MDOB approach

Abstract The neglect of subjective factors such as cost consideration and accessibility in occupant behavior models leads to unrealistic device usage simulations, which ultimately undermines prediction accuracy. To address this gap, this paper proposes a Multi-Device Occupant Beh...

A topology of digitalising territories

This paper develops a topological analysis of digitalising territories which examines the dynamic relationship between territory, land, and the digital technologies of measurement and control. We propose a conceptualisation of digitalising territories through a topological lens a...

Aflibercept 8 mg in neovascular age-related macular degeneration and diabetic macular oedema: Translating clinical trials into clinical practice

Abstract Provide expert-informed guidance on the integration of aflibercept 8 mg into routine clinical care for patients with neovascular age-related macular degeneration (nAMD) and diabetic macular oedema (DMO), based on clinical trial and real-world evidence. Sixteen retina spe...

Sample-efficient and generalizable velocity and pressure field reconstruction from three-dimensional two-phase flow interfaces

Abstract Accurate reconstruction of velocity and pressure fields from gas-liquid interfaces is essential for quantifying two-phase flow dynamics and enabling real-time flow visualization and diagnostics. This study presents a Transformer-based neural operator model pretrained on...

Theoretical study into a novel design of oscillating water column with high broadbanded efficiency

This paper considers the theoretical operation of a novel wall-mounted oscillating water column wave energy device designed to be resonant over a broad range of frequencies. A curved duct with a submerged opening in a vertical wall is partitioned into a number of separate narrow...

Moral identity and language jointly influence how bilinguals feel and decide

Abstract This preregistered study investigated how moral identity relates to moral decisions and emotional responses in 106 Greek–English bilinguals. Participants evaluated two sacrificial-harm and two honesty-based interpersonal moral dilemmas and completed the Moral Identity Qu...

Fluid Toxicities: Violent Affective Ecologies in Cartagena, Colombia

ABSTRACT Water is at the centre of climate change emergency concerns in coastal cities. It constitutes here a fluid entry point to investigating the socio‐ecological politics of toxicities for residents dwelling with and against contaminated waters in Cartagena, Colombia's urban...

Natural Sunlight IR‐Driven Highly Efficient Synthesis of Acetaldehyde From Bioethanol Over Cu/Fe 2 O 3

ABSTRACT Using renewable biomass to synthesize valuable chemicals can reduce fossil fuel dependence and achieve carbon neutrality. Here, for the first time an infrared light‐driven catalyst, Cu/Fe 2 O 3 , was designed to convert bioethanol to valuable acetaldehyde, accompanied by...

Companionship and Control: Experiencing ChatGPT as Writer-Identity Work in L2 Academic Writing

Abstract The rise of generative artificial intelligence (AI) is reshaping the landscape of academic writing. Existing research has largely emphasized functional aspects of tools such as ChatGPT (e.g., efficiency, accuracy, and plagiarism) while often overlooking how writers actua...

Artificial intelligence in pituitary surgery: the path to clinical solutions

Abstract Artificial intelligence (AI) is rapidly moving from conceptual innovation to high-performing algorithms across the pituitary patient pathway, promising benefit to patients, endocrinologists and surgeons alike. Pre-operatively, machine learning applied to facial imaging,...

Indoor smellscape interventions and designers’ intended impacts on building occupants: an exploratory review of project descriptions

Existing standards and academic research offer no guidance for intentional olfactory design. This gap is relevant because, although many indoor smells are shaped by occupants, the baseline olfactory conditions of a space can still be intentionally designed through architectural c...

The Impact Mechanisms and Paths of the National Big Data Comprehensive Pilot Zones on Urban Pollution Reduction and Carbon Mitigation

The National Big Data Comprehensive Pilot Zone (NBDCPZ) constitutes a landmark institutional initiative designed to advance and deploy data elements while strengthening governance capacity for environmental sustainability and low-carbon transition. Drawing on a panel dataset cove...

The Search for Life Elsewhere: Avoiding Hype and Fostering Public Understanding

The search for life beyond Earth presents unique challenges for science communication due to its interdisciplinary nature, the potential for groundbreaking discoveries, and the inherent uncertainties involved. The Lorentz Center workshop Breaking News: We Found Extraterrestrial L...

Delay Information Sharing in Two-Sided On-Demand Platforms

Problem Definition: We study delay information disclosure policies for on-demand platforms serving two user classes (customers and providers) who seek matches using the platform. The platform's objective is to maximize the match rate by choosing the level of information—no inform...

Tuning Cation Disorder in LiNi 0 . 5 Mn 1 . 5 O 4 via Room Temperature Continuous‐Flow Co‐Precipitation and Controlled Heat Treatment

A room temperature, continuous coprecipitation process with in‐line dynamic mixing (ACTIM) was used to synthesize a precursor (up to 0.42 kg h −1 ) to the high‐voltage cathode LiNi 0 . 5 Mn 1 . 5 O 4 (LNMO), consuming ~39% less energy at the coprecipitation step than a more conve...

Potentiation effects of the positive allosteric modulator PTC‐174 on NMDA receptors in neonatal male rat substantia nigra dopaminergic neurons

Abstract Background and Purpose Positive allosteric modulators bind to secondary binding sites on the receptor and alter receptor conformation and activation, changing agonist potency and efficacy. PTC‐174 is a novel NMDA receptor positive allosteric modulator that particularly e...