University College London

‘Africans Against Malaria’—introducing a new diaspora-led initiative to strengthen malaria prevention amongst UK-based travellers visiting friends and relatives in malaria-endemic African countries

Use of malaria prevention methods, particularly chemoprophylaxis, amongst the UK-based African diaspora is low; a long-standing issue that remains inadequately addressed. Here, we present ‘Africans Against Malaria’, a unique initiative ‘led by Africans, for Africans’ to improve m...

Sensing in fluidized bed processes — from capturing details to monitoring the operation

This article offers an opinion and a perspective on the future development of sensing techniques in fluidization technology. The direction of the field is exemplified by a handful of techniques, pointing at the advancements that revolve around two aspects. First, increasing the b...

Total intravenous versus volatile anesthesia in living donor hepatectomy: A global prospective cohort study from the international LDLT registry

The choice between total intravenous anesthesia (TIVA) and volatile anesthesia for living donor hepatectomy remains controversial, with limited evidence comparing their impact on donor and recipient outcomes. This study evaluates the association between anesthetic technique and e...

Association between injury and depression in ageing population: longitudinal evidence from the Czech HAPIEE study

Abstract Background Experiencing an injury can have profound and lasting effects on both physical and mental health. This impact is pronounced in ageing population, where an injury can substantially diminish quality of life. Given the vulnerability of this population, it is cruci...

Machine learning forecasts suggest a concentration paradox in international student mobility to the United Kingdom

Abstract International student mobility is central to higher education finance, soft power, and knowledge production, yet future demand is increasingly uncertain. We analyse Universities and Colleges Admissions Service records on successful international undergraduate application...

Teaching the visual culture of food influencing and clean eating: critical approaches to learning in action

The article presents critical analysis of clean eating’s visual culture and classroom discussions, to explore the informal learning that arises from constructions of white femininity and food curation, promoted by clean eating influencers’ social media channels, cookery books, an...

Identifying Autism in Women Diagnosed with Borderline Personality Disorder: Clinician and Lived Experience Perspectives

Background: Growing numbers of people with a borderline personality disorder (BPD) diagnosis are querying whether they have undiagnosed autism. Previous qualitative research has not focused on identifying barriers and facilitators to this diagnostic journey, has not explored the...

Macular neovascularisation subtype determines visual consequences of early fibro-atrophic remodelling in neovascular AMD: PRECISE study report 11

Abstract Purpose To evaluate whether baseline well-delineated hyperreflective material (wdHRM) is associated with short-term visual outcome in treatment-naïve neovascular age-related macular degeneration (nAMD), whether this association differs by macular neovascularisation (MNV)...

Directed Oxidative Folding of Disulfide-Rich Peptides (DRPs) Using a Pseudoproline Unit: Ion Mobility-Mass Spectrometry (IM-MS) Reveals the Conformational Landscape of the DRP

Abstract Disulfide-rich peptides (DRPs) are attractive drug development scaffolds due to their exceptional stability and specificity. Regioselective disulfide bond formation is often achieved via orthogonal Cys protecting groups or strategic Pro placement. However, Cys protection...

Generalizable and equitable automated ischaemic stroke lesion segmentation with vision transformers

Abstract Background Ischaemic stroke, a leading cause of death and disability, relies on neuroimaging for characterising the anatomical pattern of injury. Diffusion-weighted MRI (DWI) provides the most anatomically specific signal in acute ischaemic stroke but poses substantial c...

Beyond Ce–U Charge Transfer: Strain and Polarons in Epitaxial Ce1– x U x O2(111)

Abstract The redox chemistry of mixed ceria-based oxides is commonly interpreted in terms of direct charge transfer between neighboring cations. In the Ce1–xUxO2 system, this corresponds to the oxidation of U4+ into U5+ accompanied by the reduction of Ce4+ into Ce3+. In this work...

Comparing the utility of FDG PET-CT and contrast-enhanced CT in patients with oesophagogastric adenocarcinoma treated with neoadjuvant chemotherapy

Abstract Background 2-deoxy-2[ 18 F]fluoro-D-glucose positron emission tomography-CT (FDG PET-CT) is established in staging oesophagogastric adenocarcinoma. It has an emerging role in assessing response to neoadjuvant chemotherapy (NACT) but its benefits over contrast-enhanced CT...

Possible pelagic lifestyle of the Silurian trilobite Deiphon evaluated through three-dimensional modeling

Abstract Many euarthropods have evolved pelagic lifestyles, but evaluating this in extinct taxa relies on documenting a broad distribution in diverse lithologies, occurrence across multiple paleobiogeographic regions, functional morphology, and morphological comparisons to modern...

Clinical efficacy/effectiveness, safety, and health-related quality of life associated with relapsed/refractory pediatric low-grade glioma treatments: systematic literature review

Abstract Background Patients with relapsed/refractory pediatric low-grade glioma (R/R pLGG) face considerable long-term morbidity. Most cases are driven by mitogen-activated protein kinase (MAPK) pathway alterations, for which several targeted agents have been evaluated. Systemat...

International Protocol for the Study of Amorphous Charred Objects in Archaeology (IPSACO 1.0)

Abstract Archaeobotanists around the world increasingly recognise that, alongside commonly studied materials such as seeds, fruits, wood charcoal, and chaff, archaeobotanical samples also contain fragments of carbonised organic (and sometimes inorganic) matter that vary in shape...

Invited submission to Reproduction and Fertility for “Evolving Perspectives in Management of Menopause Transition” Series

Abstract Menopause following cancer treatment is an increasingly recognised component of survivorship yet remains under-addressed in clinical care. The aim of this review is to synthesise current evidence on menopause induced by cancer treatment, by bringing together current evid...

Psychological interventions for harmful gambling: Systematic review and network meta-analysis

Abstract Background and aims Gambling causes harms for the individual, their families and wider society. Psychological interventions have been shown to improve gambling severity, but their relative effectiveness is not well understood. Methods Systematic review and network meta-a...

Mathematical Explanations and Axioms as Rules

Abstract This paper bridges two distinct traditions – philosophy of mathematics and proof theory – to provide a formal framework for explanatory proofs in mathematics. We focus on explanatory proofs that uncover the grounds of mathematical theorems, and we formalize their structu...

Can Visual Clusters Support Semantic Steering? A Cross-Scale Study of Responsive Façade Images

Active responsive façades are commonly classified by function or technology, while their visual organization across component and whole-façade scales remains underexplored. This study asks whether image features can organize cross-scale differences and whether cluster-derived sem...

How Does the Time from Intraoperative Culture Harvest to Incubation Impact Culture Positivity in Orthopaedic Surgeries? A Case–Control Study

Background: Orthopaedic infections require accurate microbiological diagnosis for effective treatment. This study aimed to evaluate the impact of an accelerated protocol for culture harvesting and incubation on culture positivity rates in orthopaedic surgeries, comparing it to th...