Tsinghua University

Deciphering the Roleof Hydrophobic Amino Acid l -Methionine in Tuning CO2 Hydrate Kinetics:Insights from Molecular Dynamics Simulations

Abstract CO2 clathrate hydrate has emerged as a promising medium for carbon sequestration owing to its exceptionally high CO2 storage capacity and intrinsic stability in subsea environments. Sluggish growth kinetics hinder its field application and large-scale deployment. The hyd...

Reversible Oxygen Redoxin High Voltage for Lithium-RichLayered Oxides

Abstract Lithium-rich layered oxides, characterized by Li ions in the transition-metal layers, can significantly increase battery energy density through the introduction of oxygen redox. However, these cathodes often suffer from substantial voltage hysteresis, leading to a consid...

Mechanics-Permeability Similarities Between Natural-like and Natural Coal–Rock Specimens—A Comparative Study

Investigating the mechanics-permeability similarities between natural-like and natural gas-bearing coal–rock specimens provides a theoretical basis for using natural-like specimens as substitutes for natural ones in laboratory simulations of the incubation of coal–rock gas compos...

Metabolic-extracellular matrix crosstalk in hepatocellular carcinoma: mechanisms and targeted intervention

Bidirectional crosstalk between metabolic reprogramming and extracellular matrix (ECM) remodeling in hepatocellular carcinoma (HCC) constitutes an important metabolic–ECM regulatory network that contributes to HCC progression. Metabolic derangements disrupt ECM deposition, crossl...

Ag-iPyramidSERS Enables Single-Particle Detectionof Sub-200 nm Nanoplastics in Real Samples

Abstract The detection of nanoplastics smaller than 200 nm is critical because of their potential to cross biological barriers, yet it remains a significant analytical challenge in complex environmental matrices due to weak signals and matrix interference. Here, we developed an o...

Extreme heat, supply chain risks and enterprise performance

This paper examines the impact of exposure to high temperatures on the performance of downstream enterprises. By constructing “supplier-customer” pairs during 2010-2019, we explore exogenous variation in temperature and find that high temperatures in suppliers' regions significan...

Mechanisms and therapeutic strategies of asthma: from bench to bedside

Asthma is a heterogeneous chronic airway disease arising from a complex interplay of genetic susceptibility and environmental exposures. Key pathobiological features include dysregulated immune responses (particularly type 2 inflammation), structural airway remodeling, and mucus...

Spin-quenching cobalt center for efficient ammonia synthesis derived from oxide mixology

The spin polarization plays a critical role in heterogeneous catalysis by influencing the properties of active sites and thereby altering catalytic performance. However, precise construction of active sites with well-tuned spin states remains challenging. Here we demonstrate to m...

Share pledge, information advantage, and brokers’ SEO underwriting competition

This study investigates how brokerage firms’ involvement in share pledge transactions affects their competitiveness in underwriting seasoned equity offerings (SEOs). We find that brokerage firms acting as pledgees are more likely to serve as underwriters for issuers whose blockho...

Integrated inference of cellular compositions and gene expression programs by deconvolution

While computational deconvolution is routinely used to estimate cell-type proportions from tissue mixtures, reconstructing cell-type-specific transcriptomes at single-sample resolution remains a fundamentally underdetermined algorithmic challenge. Consequently, accurate single-sa...

Bubble‐Assisted Dynamic Confinement Enables Programmable Solid‐State Photoswitching and Heterogeneous Photoresponsive Architectures

Achieving programmable photoisomerization of azobenzenes in the solid-state remains a long-standing challenge for photoresponsive materials. Here, we introduce a dynamic soft-confinement strategy using bubble-assisted assembly to manipulate molecular aggregation via tunable surfa...

Recent Advances in the Synthesis, Isolation, and StructuralRegulation of Atomically Precise Coinage Metal Nanoclusters

Abstract Ligand-protected coinage metal nanoclusters are ultrasmall (<3 nm) materials that occupy the transitional domain between molecular complexes and nanoparticles. Traditional synthetic methodologies for creating atomically precise nanoclusters, such as the two-phase...

Sulfur-PassivatedSuperatomic Rh13S8± Clusterswith Enhanced Stability and UniqueElectronic Properties

Abstract Metal sulfides have attracted considerable attention in nanomaterials because of their unique properties supporting key applications in catalysis, energy storage, sensing and others. Thiol-protected metal clusters feature similar metal–sulfur bonding as in nanomaterials,...

Nonreciprocityof Domain-Wall Motion Induced by InterlayerDzyaloshinskii–Moriya Interaction

Abstract The Dzyaloshinskii–Moriya interaction (DMI) stabilizes chiral spin textures, making it essential for spintronic devices. Interlayer DMI is an antisymmetric exchange interaction between separated magnetic layers. However, its influence on spin–orbit torque-driven domain w...

A Heterogeneous Metal–LigandBifunctional Catalystfor Chemoselective Hydrogenation of α,β-Unsaturated Aldehydes

Abstract The concept of metal–ligand bifunctional catalysts has been extensively explored in homogeneous catalysis, yet it has not been reported in conventional heterogeneous catalysis. Inspired by the outer-sphere hydrogenation mechanism in homogeneous metal–ligand bifunctional...

A BifunctionalKeggin-Type POM-Based Cu(II) Complexfor Oxidizing Phenolic Compounds and Trace Detecting Phenol

Abstract Given the broad applications of p-benzoquinones in medicine and materials, developing efficient and environmentally benign catalysts for their synthesis from phenolic compounds is of great significance. Herein, a polyoxometalate (POM)-based Cu(II)-complex (POMOC), formul...

An ElectronicallyCoupled Interfacial Energy Descriptorfor Predicting Coulombic Efficiency in Aqueous Zinc Batteries

Abstract Solid–liquid interfaces dictate the performance and longevity of aqueous batteries. While rationally designed electrolyte additives offer a potent strategy to stabilize these interfaces, the complex interactions between additives and metal surfaces are difficult to isola...

Pan-retinal pathology detection in oct scans integrating natural language synthesis with diagnostic annotation

Abstract While OCT is pivotal for macular disease diagnosis, its adoption in primary care is limited by AI systems that cannot simultaneously analyze multi-sectional scans across the full spectrum of maculopathies or generate diagnostically integrated reports. Here we present iOC...

Investigating Associations Between Signal Intensity of Silent MR Angiography and Hemodynamic Information From 4D Flow MRI in Brain Arteriovenous Malformation

BACKGROUND: Whether signal intensity (SI) on Silent MRA reflects hemodynamics in brain arteriovenous malformations (BAVMs) is unclear. OBJECTIVES: To evaluate the relationship between Silent MRA SI and 4D flow-derived hemodynamic parameters and examine whether Silent MRA-based me...

Deep Learning in Lunar Regolith Image Processing: A Review

Recent lunar missions have generated a growing demand for automated and reliable processing of lunar regolith images. However, imaging degradations, limited annotations, and the lack of paired clean–degraded reference data still hinder the robustness and transferability of existi...