Tsinghua University

Viscoelasticity-guided covalent assembly of atomically precise nanoclusters via nitrene-mediated two-photon lithography

The translation of atomically precise metal nanoclusters into functional macroscopic devices is restricted by the difficulty of scaling manufacturing while preserving fragile quantum structures. Although two-photon lithography offers a route for micro-fabrication, the absence of...

A MultitaskLarge Reasoning Model for Molecular Science

Abstract Artificial intelligence in molecular science must move beyond pattern recognition toward chemically valid and interpretable reasoning. We present a task-adaptive large reasoning model that integrates chemical knowledge through a synergistic multispecialist architecture,...

Engineering Hidden Ferroelectric‐Like Distortion for Ultralow Thermal Conductivity in Polar van der Waals Tetradymite

ABSTRACT Ferroelectric‐like polar structures enable diverse functionalities through coupling with charge and phonon transport. Although effective in modulating thermal conductivity, the rational design of novel polar materials with intrinsically low thermal conductivity via ferro...

Tuning Reaction Pathways by Controlling Atomic Assembly on Oxide Clusters

ABSTRACT Precisely controlling the assembly of atomic sites on oxide clusters (< 1 nm) represents an expanded yet challenging strategy for tuning catalytic performance. Here, we construct two well‐defined model catalysts, single‐atomic Pt on CuO x clusters (Pt 1 ‐CuO x /CN) an...

Magnetically Tunable Chiral Phonon Polaritons withMagneto-Optical Bound States in the Continuum

Abstract Chiral phonon-polaritonic states are of interest for handedness-dependent light–matter interactions, yet their realization and magnetic control remain challenging, while direct magneto-optical tunability of phonon-polaritonic media is limited. Here, we propose a hybrid p...

Fructose directly remodels the translocase of the outer membrane to impair oxidative phosphorylation in podocytes

Excessive dietary fructose consumption contributes to the rapidly increasing prevalence of obesity, metabolic syndrome, and chronic kidney disease worldwide, and accumulating preclinical evidence has confirmed that excess fructose exposure provokes severe mitochondrial dysfunctio...

Overwhelmed and Exhausted: Exploring the Antecedents and Outcomes of Information Fatigue Through the Stressor-Strain-Outcome Model

Despite digital platforms increasingly optimizing for engagement, less work has addressed how users experience and adapt to the resulting fatigue. This qualitative study employs the Stressor-Strain-Outcome (SSO) model to investigate information fatigue in digital environments. Fo...

Towards unified AI-driven fracture mechanics: the extended deep energy method (XDEM)

Abstract Physics-Informed Neural Networks (PINNs) have recently emerged as powerful tools for solving partial differential equations (PDEs), with the Deep Energy Method (DEM) proving especially effective in fracture mechanics due to its energy-based formulation. Despite these adv...

Label-free dynamic cell imaging of fresh ex vivo spinal meningiomas: a nine-case optical-pathological correlation study with specimen-level H&E references

Spinal meningioma subtype and grade still rest on haematoxylin and eosin (H&E) morphology, but permanent sections become available only after fixation and embedding, and intraoperative assessment of fresh tissue relies mainly on frozen section. Dynamic cell imaging (DCI), a label...

A Deep‐Learning‐Based Wind Gust Estimation Scheme in Complex Terrain

Abstract Accurate prediction of gusts is critical for risk mitigation, but the turbulent processes that generate gusts are unresolved in conventional numerical weather prediction models. Here we introduce a deep‐learning‐based wind gust estimation scheme (DL‐GUST) that uses archi...

Sustainable Recovery of Platinum Group Metals via Oxysalt Phase Reconstruction and Subsequent Deep Eutectic Solvent Leaching

Abstract The recycling of platinum group metals (PGMs) underpins sustainable development across semiconductors, new energy devices, and catalytic materials. Efficiently enriching and extracting these sparsely distributed PGMs from solid wastes such as spent catalysts still pose a...

Astragalus Membranaceus Residue-Derived Biochar Supporting Atlantibacter hermannii XJ08 for Synergistic MultimetalImmobilization and Soil Quality Improvement

Abstract Soil contamination by Cd and Pb poses significant risks to ecological security and human health. Herein, a series of modified biochar (AMBC) were synthesized from Astragalus membranaceus residues, and subsequently employed as carriers of Atlantibacter hermannii XJ08 to c...

Quantifying the Correlation Between Capacity Utilization and Electrolyte Dosage for Ultrahigh‐Energy‐Density 769 Wh Kg −1 Rechargeable Lithium Metal Batteries

ABSTRACT The pursuit of high‐energy‐density lithium metal batteries requires simultaneous optimization of electrode architecture, electrolyte formulation, and interfacial stability. Here, we establish a fundamental parameter g(σ e , D e ) that quantifies the relationship between...

Endothelial cell-microglia crosstalk mediates heart failure-associated synaptic loss and cognitive impairment in male mice

Cognitive impairment affects 30%–80% of patients with heart failure, yet the mechanisms beyond reduced brain blood flow remain poorly defined. Here we show that circulating factors released during heart failure trigger senescence of brain blood-vessel endothelial cells, which in...

Effects of acupuncture on brain function in patients with depression

Background: Depression poses a major global health burden. Many patients exhibit treatment resistance or experience intolerable side effects with standard therapies. Acupuncture shows promise as an adjunctive therapy for depression, but its neurobiological mechanisms remain incom...

Toeplitz-structured deep unfolding network for TomoSAR 3-D reconstruction

Urban area 3-D imaging is a key application of synthetic aperture radar (SAR). Classical compressive sensing-based tomographic SAR methods rely on iterative optimization, which is computationally expensive and sensitive to hyperparameter tuning, limiting its scalability for large...

An Ejector Refrigeration and Humidification–Dehumidification Desalination Hybrid System for Ceramic Industry Waste Heat Recovery: Performance Evaluation and Parametric Analysis

The sustainable development of the ceramics industry is severely impeded by its intensive energy consumption and the concomitant deficits in cooling and freshwater resources. To address these bottlenecks, this study proposes an integrated ejector refrigeration (ER)–humidification...

Delivering building demand flexibility for grid-interactive operation: from perception and cognition to decision, execution, and verification

As both buildings and power systems undergo rapid decarbonization, demand flexibility (DF) in buildings has emerged as a key enabler for renewable energy integration, grid reliability, energy resilience, and efficient and low carbon operation. By dynamically adjusting building en...

EBV-driven Gate–License–Amplify circuit in multiple sclerosis pathogenesis

Five recent publications establish a “Gate–License–Amplify” circuit that mechanistically links Epstein–Barr virus (EBV) infection and genetic risk (HLA-DR15) to the pathogenesis of multiple sclerosis (MS). 1 , 2 , 3 , 4 , 5 This new model reveals how EBV reprograms immunopeptidom...

Tracking the baryon number with nuclear collisions

Baryon quantum number is found to be conserved since baryogenesis in the early Universe. Conventionally, each fractionally charged valence quark is understood to carry one-third of a baryon number. An alternative hypothesis posits that baryon number is instead carried by a baryon...