Tsinghua University

A MultitaskLarge Reasoning Model for Molecular Science

Abstract Artificial intelligence in molecular science must move beyond pattern recognition toward chemically valid and interpretable reasoning. We present a task-adaptive large reasoning model that integrates chemical knowledge through a synergistic multispecialist architecture,...

Magnetically Tunable Chiral Phonon Polaritons withMagneto-Optical Bound States in the Continuum

Abstract Chiral phonon-polaritonic states are of interest for handedness-dependent light–matter interactions, yet their realization and magnetic control remain challenging, while direct magneto-optical tunability of phonon-polaritonic media is limited. Here, we propose a hybrid p...

Towards unified AI-driven fracture mechanics: the extended deep energy method (XDEM)

Abstract Physics-Informed Neural Networks (PINNs) have recently emerged as powerful tools for solving partial differential equations (PDEs), with the Deep Energy Method (DEM) proving especially effective in fracture mechanics due to its energy-based formulation. Despite these adv...

Label-free dynamic cell imaging of fresh ex vivo spinal meningiomas: a nine-case optical-pathological correlation study with specimen-level H&E references

Spinal meningioma subtype and grade still rest on haematoxylin and eosin (H&E) morphology, but permanent sections become available only after fixation and embedding, and intraoperative assessment of fresh tissue relies mainly on frozen section. Dynamic cell imaging (DCI), a label...

Delivering building demand flexibility for grid-interactive operation: from perception and cognition to decision, execution, and verification

As both buildings and power systems undergo rapid decarbonization, demand flexibility (DF) in buildings has emerged as a key enabler for renewable energy integration, grid reliability, energy resilience, and efficient and low carbon operation. By dynamically adjusting building en...

Sustainable Recovery of Platinum Group Metals via Oxysalt Phase Reconstruction and Subsequent Deep Eutectic Solvent Leaching

Abstract The recycling of platinum group metals (PGMs) underpins sustainable development across semiconductors, new energy devices, and catalytic materials. Efficiently enriching and extracting these sparsely distributed PGMs from solid wastes such as spent catalysts still pose a...

Astragalus Membranaceus Residue-Derived Biochar Supporting Atlantibacter hermannii XJ08 for Synergistic MultimetalImmobilization and Soil Quality Improvement

Abstract Soil contamination by Cd and Pb poses significant risks to ecological security and human health. Herein, a series of modified biochar (AMBC) were synthesized from Astragalus membranaceus residues, and subsequently employed as carriers of Atlantibacter hermannii XJ08 to c...

EBV-driven Gate–License–Amplify circuit in multiple sclerosis pathogenesis

Five recent publications establish a “Gate–License–Amplify” circuit that mechanistically links Epstein–Barr virus (EBV) infection and genetic risk (HLA-DR15) to the pathogenesis of multiple sclerosis (MS). 1 , 2 , 3 , 4 , 5 This new model reveals how EBV reprograms immunopeptidom...

An Ejector Refrigeration and Humidification–Dehumidification Desalination Hybrid System for Ceramic Industry Waste Heat Recovery: Performance Evaluation and Parametric Analysis

The sustainable development of the ceramics industry is severely impeded by its intensive energy consumption and the concomitant deficits in cooling and freshwater resources. To address these bottlenecks, this study proposes an integrated ejector refrigeration (ER)–humidification...

Quantifying the Correlation Between Capacity Utilization and Electrolyte Dosage for Ultrahigh‐Energy‐Density 769 Wh Kg −1 Rechargeable Lithium Metal Batteries

ABSTRACT The pursuit of high‐energy‐density lithium metal batteries requires simultaneous optimization of electrode architecture, electrolyte formulation, and interfacial stability. Here, we establish a fundamental parameter g(σ e , D e ) that quantifies the relationship between...

Effects of acupuncture on brain function in patients with depression

Background: Depression poses a major global health burden. Many patients exhibit treatment resistance or experience intolerable side effects with standard therapies. Acupuncture shows promise as an adjunctive therapy for depression, but its neurobiological mechanisms remain incom...

A Deep‐Learning‐Based Wind Gust Estimation Scheme in Complex Terrain

Abstract Accurate prediction of gusts is critical for risk mitigation, but the turbulent processes that generate gusts are unresolved in conventional numerical weather prediction models. Here we introduce a deep‐learning‐based wind gust estimation scheme (DL‐GUST) that uses archi...

Toeplitz-structured deep unfolding network for TomoSAR 3-D reconstruction

Urban area 3-D imaging is a key application of synthetic aperture radar (SAR). Classical compressive sensing-based tomographic SAR methods rely on iterative optimization, which is computationally expensive and sensitive to hyperparameter tuning, limiting its scalability for large...

Endothelial cell-microglia crosstalk mediates heart failure-associated synaptic loss and cognitive impairment in male mice

Cognitive impairment affects 30%–80% of patients with heart failure, yet the mechanisms beyond reduced brain blood flow remain poorly defined. Here we show that circulating factors released during heart failure trigger senescence of brain blood-vessel endothelial cells, which in...

UltrafastSwitchable Polar and Magnetic Orders byNonlinear Light–Matter Interaction

Abstract An outstanding challenge in materials science and physics is the harnessing of light for switching ferroic orders in, e.g., ferroelectrics. Here, we propose a mechanism through which electrons in few-layer 2D materials excited with above-bandgap light cause ionic structu...

Divergent drivers of runoff changes in the Indus eastern tributaries: Insights from attribution analysis based on the Budyko framework

Study region The eastern tributaries of the Indus River Basin: Chenab, Jhelum, Ravi, and Sutlej. Study focus Using discharge records from the Water and Power Development Authority, Pakistan and climatic data from reanalysis datasets, this study constructs long-term, up-to-date hy...

Uncertainty in Land Carbon Fluxes Simulated by CMIP6 Models from Treatments of Crop Distributions and Photosynthetic Pathways

Abstract. A reliable representation of the diversity of vegetation in terrestrial ecosystems is needed for the accurate simulation of present and future biogeochemical cycling and global climate, particularly as climate change affects different vegetation types differently. We co...

Stakeholder perceptions of an early essential newborn care simulation-based training in western China: a qualitative study

Neonatal mortality remains a global concern, especially in China, where regional disparities persist. Early essential newborn care (EENC) consists of a set of evidence-based and cost-effective interventions, including but not limited to, skin-to-skin contact, neonatal resuscitati...

Extending the sensitivity of heavy sterile neutrino searches with solar neutrino experiments

Abstract A sensitivity study of the search for heavy sterile neutrinos ($\nu_H$) in the MeV mass range using solar neutrino experiments is presented. $\nu_H$, with masses ranging from a few MeV up to around 15 MeV, can be produced in the Sun through $^8$B decay and subsequently d...

Light‐Absorbing‐Layer‐Free Flash Lamp Annealing for High‐Throughput Fabrication of All‐Solution‐Processed Oxide Electronics

ABSTRACT Metal oxides exhibit high transparency across the visible spectrum, making them challenging to anneal via flash lamp annealing (FLA). Whether such materials can effectively absorb light and self‐heat remains debated. Conventional workarounds often involve light‐absorbing...