Tsinghua University

PhosphorusChemistry and the Origin of Life: From N -PhosphorylAmino Acid to Protocell

Conspectus A central question in origin-of-life research is how biological macromolecules and cellular structures arose from simple precursors under prebiotic conditions. This review focuses on the chemical evolution model of N-phosphoryl amino acids (NPAAs) and their multifacete...

Bioinspired architected catalyst for efficient water purification: Bridging reactivity, reusability, and catalytic component utilization

Achieving highly efficient water purification remains a formidable challenge due to intricate coupling among catalytic efficiency, mechanical robustness, and mass transport. Here, we create a bioinspired architected catalyst featuring microscale shell-based frameworks with atomic...

Gas–Solid Two-Phase Flow-Induced Pipeline Wear in CAES: Enhancing Long-Term Durability for Energy Conversion and Storage Integration

In salt cavern compressed air energy storage (CAES) systems, slag particles entrained by high-pressure airflow can cause pipeline wear and flow instability, posing challenges to long-term operational safety. However, direct experimental studies are constrained by high-pressure, l...

Islands and traversable wormholes

A bstract We study information recovery in black hole evaporation using traversable wormhole protocols in AdS 2 Jackiw-Teitelboim gravity with matter fields coupled to an external bath. By introducing a simple non-local interaction between left and right radiation regions, we gen...

Speed of Sound and Derived Virial Coefficients ofDifluoromethane (R32) + trans -1,3,3,3-Tetrafluoropropene(R1234ze(E)) and Difluoromethane (R32) + Hexafluoropropylene (R1216)Binary Mixtures in Vapor Phase

Abstract Binary mixtures of difluoromethane (R32) with hydrofluoroolefins (HFOs) possess excellent thermodynamic performance and low global warming potential, supporting the reduction of hydrofluorocarbons (HFCs) usage. In this work, the gaseous speed of sound was measured for R3...

Brain‐Mimetic Mapless Navigation Framework Integrating Visual Streams and Entorhinal‐Hippocampal‐Prefrontal Circuits

ABSTRACT Efficient autonomous navigation in complex and unstructured environments without pre‐existing maps remains a significant challenge for mobile robotics. Drawing inspiration from rodent neural architectures, this study proposes a brain‐mimetic mapless navigation framework...

MedKGent: a large language model agent framework for constructing temporally evolving medical knowledge graph

The rapid expansion of medical literature challenges the scalable structuring of domain knowledge. Knowledge Graphs (KGs) offer a solution, yet current construction methods lack generalizability and ignore the temporal dynamics of evolving knowledge. To address this, we introduce...

A systematic scoping review of transformative potential and contextual challenges of integrating AI and collective intelligence in African higher education

The integration of artificial intelligence (AI) into African higher education is characterized by a critical tension between its transformative potential and profound contextual constraints. This systematic scoping review addresses this disjuncture by synthesizing available evide...

Long-Term Evidence of ENSO-Driven Rodent Population Dynamics in a Natural Plague Focus of Southwestern China

Climate variability can modulate zoonotic disease risk by altering interactions among wildlife hosts, vectors, and human environments, yet long-term evidence linking large-scale climate oscillations to natural plague systems remains scarce. We investigated the influence of El Niñ...

Multi-Objective Optimization of Nozzle Closing Strategies for High Head Pelton Turbines to Shorten the Nozzle Closing Time and Mitigate Water Hammer Effects

The rapid shutdown of high-head and large-capacity Pelton turbines equipped with long penstocks often induces severe water hammer effects, threatening the structural safety of the diversion system. Traditional linear or simple piecewise nozzle closing laws struggle to achieve an...

The effect of natural disasters on dyslipidemia: a nationwide study from China

Globally, dyslipidemia has become a leading risk factor for many adverse health outcomes, especially among middle-aged and elderly populations. Accumulating evidence suggests that environmental-level factors may also be associated with the risk of dyslipidemia. Although natural d...

Longitudinal dynamics of the maternal gut virome associate with metabolic features of preterm birth

Preterm birth (PTB) remains a major pregnancy complication, yet the role of the maternal gut virome in its etiology is largely unknown. Here we show that the maternal gut virome undergoes ecological destabilization prior to PTB, coupled with distinct host metabolic remodeling. Ne...

Competitive crystallization‑orchestrated gypsum cryogels for next‑generation building envelopes

The growing demand for climate-resilient and functionally reliable buildings requires envelope materials to integrate thermal regulation, mechanical integrity, fire safety, environmental stability, and electromagnetic protection within lightweight porous structures. Herein, we re...

Dynamic expression of IL-21 in effector CD8 T cells helps control chronic infections

CD8 T cells are critical players in immune responses against pathogens. Interleukin-21 (IL-21) is predominantly produced by CD4 T cells and exerts multifaceted effects on CD8 T cell regulation and function. Using Il21 -reporter and Il21 –fate mapping mice, we report that a subpop...