Sapienza University of Rome

The Role of Transparency in Repeated First-Price Auctions with Unknown Valuations

Abstract. We study the problem of regret minimization for a single bidder in a sequence of first-price auctions where the bidder discovers the item’s value only if the auction is won. Our main contribution is a complete characterization, up to logarithmic factors, of the minimax...

Antileishmanial activity of gold(I) compounds containing triphenylphosphine ligands against Leishmania amazonensis: impacts on mitochondrial bioenergetics and trypanothione reductase activity

Abstract Leishmaniasis poses a significant public health challenge, highlighting the urgent need for safer and more effective therapies. Here, we investigated the antileishmanial activity and mechanism of action of gold(I)-triphenylphosphine complexes against Leishmania amazonens...

A Multi‐Software Approach to Assessing Photovoltaics Integration in Modern Enovoltaic Systems

ABSTRACT Land competition has intensified over the past two decades due to population growth, urbanization, and the push for renewable energy. The growing tension among food, energy, and land demands calls for integrated solutions. One of such approaches is agriphotovoltaics, whi...

A validated 3D point‐cloud analysis workflow for the creation of seagrass canopy height models

Abstract Seagrasses support highly productive ecosystems in both temperate and tropical waters and provide essential ecosystem services. Despite their importance, the vertical structure of seagrasses (i.e. the canopy) remains poorly characterised at the microscale, even though it...

The Italian Nanomedicine Platform (INP): national integration within the European nanomedicine ecosystem

Italy’s nanomedicine expertise has long developed in fragmented manner, with limited coordination across academia, clinical institutions, industry and regulatory bodies. The Italian Nanomedicine Platform (INP) was established to integrate discovery, preclinical validation, regula...

Ultrasound‐Based Skeletal Muscle Assessment for Prognostication in Cirrhosis: A Systematic Review

BACKGROUND AND AIMS: Sarcopenia is a major determinant of adverse outcomes in cirrhosis, yet CT- and MRI-based assessments are difficult to implement in routine and longitudinal practice. Ultrasound is a feasible bedside alternative, but its prognostic role remains unclear. We pe...

How does labour force participation respond to unemployment? A regional and gender-based exploration of Italy

Abstract This study examines whether, and how, unemployment dynamics shape labour force participation across Italian macro-regions, asking whether added or discouraged worker effects prevail and whether participation responds persistently to unemployment shocks. Using quarterly d...

How Gaussian can our Universe be?

Gravity is a non-linear theory, and hence, barring cancellations, the initial super-horizon perturbations produced by inflation must contain some minimum amount of mode coupling, or primordial non-Gaussianity. In single-field slow-roll models, where this lower bound is saturated,...

Impact of Aortic Annulus Size on Clinical and Hemodynamic Outcomes of Transcatheter Aortic Valve Implantation With the Navitor Valve

ABSTRACT Background Patients with small aortic annuli undergoing transcatheter aortic valve implantation (TAVI) are at risk of higher residual transvalvular gradients. Evidence on the performance of new‐generation intra‐annular self‐expanding valves in this anatomical setting rem...

The added value of echocardiography in pulmonary arterial hypertension risk assessment an artificial intelligence machine learning–derived analysis of the ULTRA RIGHT VALUE registry

Abstract Aims The right ventricle (RV) is a major determinant of outcome in pulmonary arterial hypertension (PAH), but its assessment has not been completely incorporated in the risk of mortality scores. We therefore evaluated the added value of echocardiography of the RV to risk...

Environmental Sustainability-Related Knowledge, Behaviors, and Perceived Barriers Among Italian Intensive Care Unit Nurses: A Cross-Sectional Survey

Background/Objectives: Healthcare systems are increasingly recognized as contributors to climate change, and intensive care units represent particularly resource-intensive clinical environments. Nurses play a central role in shaping daily care practices that may influence the env...

Palmitoylethanolamide as an Intestinal Gatekeeper: Linking Inflammation, Angiogenesis and Colorectal Cancer Interception

Angiogenesis is a major determinant of tumor growth, progression and metastatic potential, and its persistent activation is closely intertwined with chronic inflammation. This relationship is particularly relevant in malignancies that arise through a prolonged inflammation-to-car...

Low Cycle Fatigue Reliability of Dissimilar Weldments Made by ZG18CrNiMoA Cast Steel and Q355D Structural Steel

ABSTRACT Cast steel combines high strength and ductility, enabling flexible designs for heavily loaded structural components, yet the low‐cycle fatigue (LCF) performance of its welded component remains insufficiently understood. This study experimentally examines Q355D structural...

Reactive Extrusion of Injection-Grade Polypropylene Toward Controlled-Rheology Materials for Spunbond Manufacturing

The spunbond process is one of the main technologies for producing polypropylene (PP)-based nonwoven fabrics, widely used in industrial applications and in the automotive sector. In this work, an injection-molding-grade polypropylene was modified through the addition of 0.5 wt% N...

A Methodological Reference Framework for Identifying and Valuing Intangible Benefits in Cost–Benefit Analysis of Public Health Interventions

Cost–benefit analysis (CBA) is a primary tool for appraising public investments, yet its reliability weakens when interventions generate benefits that are intangible and difficult to monetize. The challenge is acute in public health, where outcomes such as reduced mortality and m...

Moving bottlenecks in traffic flows: a well-posed fully coupled nonlocal PDE-ODE model with time delay

We propose a nonlocal PDE-ODE strongly coupled system describing the interaction between traffic flow and a moving bottleneck, induced by e.g. a controlled vehicle. The bulk traffic density evolves according to a nonlocal scalar conservation law with time delay, while the bottlen...

Divergent structure–function coordination shapes leaf thermal tolerance in Mediterranean tree species

Increasing temperatures impair photosynthetic apparatus by damaging photosystem II (PSII) efficiency. We evaluated the relevance of two thermal indices (Tcrit and T50) as indicators of the PSII resistance to thermal stress of Quercus ilex, Acer campestre and Fraxinus ornus in the...

Low-Molecular-Weight Heparin Versus Unfractionated Heparin for Venous Thromboembolism Prophylaxis in Adult Traumatic Brain Injury: A Systematic Review and Meta-Analysis

BACKGROUND AND OBJECTIVES: Traumatic brain injury (TBI) is associated with a high risk of venous thromboembolism (VTE), yet the optimal strategy for thromboprophylaxis remains uncertain. Low-molecular-weight heparin (LMWH) and unfractionated heparin (UFH) are commonly used agents...

Early Versus Delayed Oxytocin Augmentation in Nulliparous Women with Spontaneous Dysfunctional Labour: A Systematic Review and Meta-Analysis

Background: The timing of oxytocin for slow labour progress rests on custom rather than evidence, and existing syntheses pool clinically distinct populations. Objectives: We restricted this systematic review to nulliparous women in established active-phase labour with a trial-spe...

Plant‐Derived Bioactives and PPAR Signaling in Functional Dyspepsia: Mechanistic Insights and Therapeutic Perspectives

ABSTRACT Functional dyspepsia (FD) is a common disorder of gut‐brain interaction in which gastric sensorimotor abnormalities may coexist with impaired duodenal barrier function, low‐grade immune activation, and altered neuroimmune signaling. Peroxisome proliferator‐activated rece...