Sapienza University of Rome

Extra Dimensions, Exotic Matter like 17MeV and Dark Matter Triple String Framework

Extra Dimensions, Exotic Matter like 17 MeV and Dark Matter Triple String Framework introduces a unified theoretical model connecting extra-dimensional geometry, exotic matter, dark-sector resonances, and cosmological anomalies. The framework is built on a binary SU(2)–CP²–SU(3)...

Extra Dimensions, Exotic Matter like 17MeV and Dark Matter Triple String Framework

Extra Dimensions, Exotic Matter like 17 MeV and Dark Matter Triple String Framework introduces a unified theoretical model connecting extra-dimensional geometry, exotic matter, dark-sector resonances, and cosmological anomalies. The framework is built on a binary SU(2)–CP²–SU(3)...

Self‐Assembly of a Colloidal Honeycomb Crystal in Silico for Topological Valley Photonics

The quest to employ colloidal self-assembly as a scalable means of fabricating photonic crystals with a complete photonic band gap at optical frequencies has proved challenging throughout the first quarter of the 21st century. Meanwhile, the field of topological photonics has eme...

Serotonergic Toxicity and Hyponatremia Associated with Antidepressant Therapy: The Pivotal Role of SIADH

Serotonin syndrome (SS) and the syndrome of inappropriate antidiuretic hormone secretion (SIADH) are well-recognized adverse drug reactions (ADRs) associated with serotonergic agents, particularly antidepressants. Although traditionally regarded as distinct clinical entities, acc...

Genetic algorithm-supervised graph shadow estimation for low-observability distribution feeders: calibrated validation on a real feeder

Real distribution feeders often operate under partial observability, while physics-based state estimators can be too slow for frequent digital-twin updates. This paper proposes a Genetic Algorithm (GA)-supervised graph surrogate for shadow state estimation using feeder topology,...

Subadditivity and optimal matching of unbounded samples

We obtain new bounds for the optimal matching cost for empirical measures with unbounded support. For a large class of radially symmetric and rapidly decaying probability laws, we prove for the first time the asymptotic rate of convergence for the whole range of power exponents p...

The Picard group of the Baily–Borel compactification of the moduli space of quasi-polarized K3 surfaces and generalizations

Abstract We investigate the Picard group of the Baily–Borel compactification of orthogonal Shimura varieties. In particular, we show that the Picard group of the Baily–Borel compactification of the moduli space of quasi-polarized K3 surfaces is isomorphic to ℤ. Notably, this cont...

Composite Likelihood Inference for Simultaneous Clustering and Dimensionality Reduction of Multivariate Mixed-Type Longitudinal Data

Abstract We propose a novel multivariate hidden Markov model (HMM) designed to analyze longitudinal mixed-type data comprising continuous and ordinal variables. Our model identifies and prioritizes discriminative dimensions, i.e., those useful for clustering, while separating the...

Competence, performance evaluation, and educational needs of middle nurse managers in the Italian healthcare system: A qualitative study

Background Existing literature highlights the essential role of middle nurse managers (MNMs) in ensuring communication, coordination, and quality within healthcare organisations, demonstrating the need for deeper insight into their competencies, educational needs, and evaluation...

Does sleep matter for recovery after stroke? Functional severity shapes the association between sleep and functional outcome during inpatient stroke rehabilitation

Abstract Background Sleep disturbances are common after stroke and have been associated with rehabilitation outcomes. The clinical meaning of post-stroke sleep duration remains unclear, as longer sleep may be associated with different clinical and functional states, including gre...

The WoKaS-Iso database: workflow for a global compilation of oxygen-18 and deuterium records in karst springs and cave drip water for enhanced understanding of karst systems

For analysing karst hydrogeological systems, observations of karst springs and cave drips are considered indispensable. In addition to hydrometric observations, knowing the oxygen and hydrogen stable isotope ratios has improved the understanding of vadose zone and aquifer dynamic...

Effects of dupilumab on nasal mucociliary clearance in severe CRSwNP: evaluation of the saccharin test as an objective outcome measure

OBJECTIVE: Chronic rhinosinusitis with nasal polyps (CRSwNP) is a chronic, relapsing condition associated with a significant impairment in quality of life. Persistent inflammation contributes to dysfunction of mucociliary clearance. Dupilumab (IL-4Rα inhibitor) is a well-establis...

Measuring Ethical Perceptions of AI in Nursing: The Development and Validation of the AI‐Ren Ethics in Healthcare (RATI) Scale

AIM: To develop and validate a culturally sensitive instrument for assessing nurses' ethical perceptions of artificial intelligence in clinical practice. METHODS: A two-phase scale development study was conducted among nurses in China. The first phase involved item generation thr...

Protocol for low-cost photographic digitization and automated HTML publication of envelope-preserved entomological museum collections

Here, we present a protocol for digitizing envelope-preserved entomological museum specimens. We describe steps for acquiring images, transcribing labels into Darwin Core records, and validating taxonomy and geography. We then detail procedures for linking images to metadata and...

Internalized weight stigma and associated clinical features in treatment-seeking adults with obesity: a multicenter Italian study

Abstract Background This study aimed to evaluate the prevalence and clinical correlates of internalized weight stigma in patients with obesity seeking treatment in various clinical centers across Italy. Methods A total of 438 patients with obesity were included. Patients complete...

The Large Deviation Principle for the Stochastic 3D Primitive Equations with Transport Noise

Abstract We prove the small-noise large deviation principle for the three-dimensional primitive equations with transport noise and turbulent pressure. Transport noise is important for geophysical fluid dynamics applications, as it takes into account the effect of small scales on...

Phenotype-based appropriateness of IGM-enriched polyclonal immunoglobulin use in critical illness: report of an expert consensus

Sepsis and septic shock result from a dysregulated host response to infection, encompassing both hyperinflammatory and immunosuppressed phenotypes. Although immunomodulatory adjunctive therapies have been extensively investigated over the past decades, none have demonstrated cons...

Amphiphilic Motif Triggers Microheterogeneity in Low‐Melting Mixtures

Microheterogeneity in low‐melting mixtures of ethylene glycol and chemically modified choline derivatives synthesized on purpose is here proposed. Novel cholinium ions with one or two N ‐butyl substituents or an N ‐hydroxybutyl chain are synthesized for the first time. Synthesis...

Alzheimer’s disease classification using dynamic geometric pattern map: A novel image representation of EEG signals

Electroencephalography (EEG) offers a non-invasive and low-cost basis for computer-aided dementia detection, but existing systems face limitations: data-dependent feature representations, deep models that process channels independently and discard inter-channel spatial topology,...

Real-world adjunctive use of an alpha-lactalbumin/sodium butyrate Food for Special Medical Purposes in drug-resistant epilepsy: the multicentre retrospective ARMILLA study

The purpose of this study was to describe real-world adjunctive use, tolerability, and hypothesis-generating seizure and multidomain outcomes of LALBAAY, an alpha-lactalbumin/sodium butyrate Food for Special Medical Purposes (FSMP), in patients with drug-resistant epilepsy (DRE)....