Sapienza University of Rome

Exploring the dimensional structure of the Thought and Language Disorder scale in acute psychiatric inpatients

Aims To explore the dimensional structure of the Thought and Language Disorder scale (TALD) in a sample of acute psychiatric inpatients and to contribute to a characterization of the latent dimensions underlying formal thought disorder (FTD). Methods A total of 250 acute patients...

Predicting levetiracetam neuropsychiatric adverse effects using graph‐theoretical electroencephalographic network metrics in drug‐naive focal epilepsy: A multicenter longitudinal study

Abstract Objective Levetiracetam (LEV) is an antiseizure medication approved for focal and generalized epilepsy. Despite its efficacy, neuropsychiatric adverse effects (NP‐AEs) may lead to treatment discontinuation. Quantitative electroencephalographic (qEEG) graph‐theoretical an...

Modulation of circulating osteocalcin-expressing monocytes by glucagon like peptide-1 receptor agonists in type 2 diabetes: an exploratory pilot study

Abstract Context The phenotypic drift of circulating monocytes toward osteoblast-like cells expressing osteocalcin (OCN) has been linked to vascular calcification in individuals with type 2 diabetes (T2D). The synergistic action of glucagon-like peptide-1 receptor agonists (GLP-1...

Construction and characterisation of the DarkSide-20k veto silicon photo-multiplier tiles

Abstract Silicon photo-multipliers (SiPMs) are state-of-the-art sensors capable of detecting a single photoelectron under cryogenic conditions, with potentially lower radioactivity than widely used photomultiplier tubes. The DarkSide-20k experiment, designed to perform direct dar...

Rapid data quality investigations of gravitational-wave events with the Data Quality Report Builder toolkit

Abstract We present the Data Quality Report Builder toolkit, DQRbuild, a suite of data quality tools that have been developed to vet gravitational-wave events in preparation for the fourth LIGO-Virgo-KAGRA observing run. We explain the main functionality and the many scientific t...

Adapting a Pretrained LLM to Rapidly Recover Earthquake Magnitude and Location

Abstract Determining earthquake magnitude and location through fast, automated methods is fundamental for seismic monitoring. Recent studies have shown that Large Language Models (LLMs) can operate as pattern‐recognition systems capable of handling novel domains and purely numeri...

Central neurocytomas: Decision-making process of postoperative treatment. Lesson learned

Central neurocytoma is a rare intraventricular tumor with favorable prognosis following gross total resection (GTR). However, the role of Ki67-MIB1 values in the postoperative decision making-process of treatment, as well as the indication for adjuvant radiotherapy, remain debate...

Prayer and acute pain sensitivity in migraine and non-migraine cohorts: two assessor-blinded crossover experiments

Prayer is a widely used coping strategy that engages affective and cognitive processes implicated in pain regulation. Despite growing interest in the effects of religion and spirituality in health research, experimental evidence linking prayer to quantitative sensory outcomes in...

In the wisdom of Odin: modular architecture, receptor trafficking and therapeutic implications

Odin (ANKS1A) is a multidomain adaptor protein originally identified as a substrate of receptor tyrosine kinases. Over the past two decades, studies have revealed functions that extend beyond canonical growth factor signaling. At the molecular level, Odin participates in receptor...

Environmental Impact Shaping a Firm's Zero Leverage Decision: Analysing Debt Demand and Supply Determinants

ABSTRACT Zero‐leverage firms remain a puzzle in corporate finance. We propose a supply‐side mechanism linking environmental impact to debt access. Because creditors favour firms with high negative externalities and strong cash flows, environmentally friendly firms with high initi...

Corporate Environmental Responsibility: How Norms Shape Collectivity and Sustainability Intentions Across Organizational and Domestic Boundaries

ABSTRACT In an era of increasing environmental challenges, organizations are expected to integrate Corporate Environmental Responsibility (CER) into their strategies and practices. This research examines employees' perceptions of CER as normative organizational signals and invest...

Genetic and Molecular Determinants of Cancer Therapy-Related Cardiovascular Toxicity

Cancer therapy-related cardiovascular toxicity (CTR-CVT) is an umbrella term for myocardial, vascular, electrical, and inflammatory complications of cytotoxic, targeted, immune, and radiation-based therapies. Cancer therapy-related cardiac dysfunction (CTRCD) is used here more na...

Antioxidant and protein anti-denaturation properties of an Algerian Opuntia ficus-indica aqueous extract: complementary in vitro and exploratory in silico analyses

Abstract Opuntia ficus-indica (L.) Mill. is a source of hydrophilic phenolic constituents with potential redox and protein-stabilising properties. The present study evaluated the antioxidant and protein anti-denaturation activities of a previously characterised aqueous extract an...

Comparative framework of solvent-assisted delamination for direct regeneration of NMC cathodes

Direct regeneration of lithium-ion battery cathodes offers a pathway to retain the embedded value of complex materials yet remains limited by inefficient separation and poorly understood surface transformations. Here, we establish a comparative framework for solvent-assisted dela...

Smoking behaviours and attitudes among dental students in three European countries: a multicentre cross-sectional study

Tobacco use remains a major public health concern and a significant risk factor for systemic and oral diseases. Dental students, as future healthcare professionals, are expected to play an important role in tobacco control and smoking cessation. This multicentre study aimed to as...

The mediational role of close teacher-student relationships in the link between loneliness and academic achievement: A longitudinal study in junior high school students

Loneliness is a well-documented risk factor for adolescents’ psychosocial and academic adjustment. However, the mechanisms through which loneliness is related to school performance remain unclear, as most prior studies have relied on cross-sectional designs. Drawing on the evolut...

Object‐Control Skills and Cortisol Response During Physical Education Lessons in Primary School Children

BACKGROUND: Object-control (OC) skills are fundamental movement skills acquired during primary school that may act as either stressors or engagement factors during physical education (PE). This study examined the acute impact of OC exercises on children's stress levels across gra...

The Italian Nanomedicine Platform (INP): national integration within the European nanomedicine ecosystem

Italy’s nanomedicine expertise has long developed in fragmented manner, with limited coordination across academia, clinical institutions, industry and regulatory bodies. The Italian Nanomedicine Platform (INP) was established to integrate discovery, preclinical validation, regula...

Antileishmanial activity of gold(I) compounds containing triphenylphosphine ligands against Leishmania amazonensis: impacts on mitochondrial bioenergetics and trypanothione reductase activity

Abstract Leishmaniasis poses a significant public health challenge, highlighting the urgent need for safer and more effective therapies. Here, we investigated the antileishmanial activity and mechanism of action of gold(I)-triphenylphosphine complexes against Leishmania amazonens...

A Multi‐Software Approach to Assessing Photovoltaics Integration in Modern Enovoltaic Systems

ABSTRACT Land competition has intensified over the past two decades due to population growth, urbanization, and the push for renewable energy. The growing tension among food, energy, and land demands calls for integrated solutions. One of such approaches is agriphotovoltaics, whi...