Sapienza University of Rome

Macroscopic fluctuation theory from a Lagrangian viewpoint and the Schrödinger problem

We formulate the Schrödinger problem for interacting particle systems in the hydrodynamical regime thus extending the standard setting of independent particles. This involves the large deviations rate function for the empirical measure which is in fact a richer observable than th...

A nationwide student survey on biochemistry learning resources in Italy

Biochemistry is widely recognized as a crucial discipline in life sciences. However, learning biochemistry poses significant challenges, requiring students to understand complex molecular concepts while integrating knowledge across multiple disciplines. This necessitates instruct...

Transoral robotic versus laser surgery for cT1-T3 supraglottic laryngeal cancers: a systematic review and meta-analysis of comparative and non-comparative studies

Background To compare literature findings about functional, oncological and surgical outcomes of transoral robotic (TORS) versus transoral laser microsurgery (TOLM) for supraglottic cT1-T3 laryngeal cancers. Methods Three independent investigators conducted a PubMed, Scopus, and...

Demographic effects of earthquakes in Central and Southern Italy

This paper evaluates the demographic effects of two major earthquakes – L’Aquila 2009 and Central Italy 2016 – that struck a large area in Central and Southern Italy. Using municipality-level data (2002–2023) and a difference-in-differences design with multiple groups and periods...

Geopolitical knowledge infrastructures and managerial decision-making: advancing the state–citizens–platforms triad

Purpose This conceptual paper examines how long-term geopolitical trends and short-term geopolitical events reshape managerial decision-making, strategic planning and organisational responses in platform-mediated environments. It theorises how states, citizens and platforms joint...

Hominin behavior, strategies, and environmental conditions in Southern Europe (Marine Isotope Stage 17–15): The 100-ka sequence of Notarchirico (Italy, 700–600 ka)

The Notarchirico sequence comprises a continuous 100-ka-long record of phases of hominin occupation between Marine Isotope Stage 17 and Marine Isotope Stage 15, revealing remarkable technological stability alongside some innovations. We analyzed core technology, raw material prov...

Ground Deformation Monitoring via Remote Sensing Time Series Data

Ground deformation is an important indicator of natural and anthropogenic processes, including land subsidence, landslides, volcanic and geothermal activity, earthquake-induced deformation, groundwater exploitation, and environmental change [...]

New species from the cradle of biodiversity inventories: cryptic diversity within Lamellariinae in the European Atlantic and Mediterranean (Gastropoda: Velutinidae)

The Mediterranean, despite a long tradition of naturalist observation dating back to Aristotle, is still home to undisclosed cryptic species complexes. The gastropod subfamily Lamellariinae d’Orbigny, 1841 (Velutinidae Gray, 1840) is composed of benthic sea slug-like species with...

Denotational Semantics for Probabilistic and Concurrent Programs

We develop a denotational model for probabilistic and concurrent imperative programs , a class of programs with standard control flow via conditionals and while-loops, as well as probabilistic actions and parallel composition. Whereas the semantics of concurrent programs and of r...

Safety and Efficacy of Acute Normovolemic Hemodilution in Female Patients

Importance Female patients undergoing cardiac surgery have a higher transfusion burden, yet they remain underrepresented in randomized clinical trials. Although the ANH trial showed no significant reduction in the proportion of patients receiving allogeneic blood transfusions wit...

The Factor Structure of the Little Developmental Coordination Disorder Questionnaire and Its Associations with Internalizing and Externalizing Difficulties and Prosocial Behavior in Preschool-Age Children in Italy

Early identification of motor difficulties is crucial, as motor competence represents a foundational developmental ski l that supports children’s participation in everyday activities and influences broader socio-emotional adjustment. Within this framework, this study examined the...

Synergistic π–π Stacking and Hydrogen Bonding of Doxorubicin Electrostatically Bound to Sodium Alginate Drive the Formation of Supramolecular Nanoparticles with Exceptional Drug Loading

Doxorubicin hydrochloride (DX) is a widely used chemotherapeutic agent whose severe side effects can be attenuated by suitably designing drug delivery systems. The complexation between DX and the biocompatible and biodegradable sodium alginate (ALG) results in the formation of DX...

A Physical Therapy Clinical Framework for Temporomandibular Disorders: Integrating DC/TMD, ICOP and Multidimensional Patient Phenotyping

Temporomandibular disorders (TMDs) are clinically heterogeneous, and patients sharing the same diagnosis may differ substantially in pain mechanisms, functional impairments, behavioral contributors, comorbidities, psychosocial burden, prognosis, and treatment response. Although t...

Training the Next Generation of Future Surgical Residents: A Scoping Review and Proposal for an Undergraduate Curriculum From the Italian Polispecialistic Society of Young Surgeons

AIM: The transition from medical school to surgical residency is marked by a persistent gap between theoretical instruction and clinical readiness. In Italy, variability in training programs across centers creates persistent gaps in residents’ medical education. Scientific societ...

A Computational Workflow Integrating Explainable AI and Database Mining for the Prioritization of Antimicrobial Natural Products

The escalating threat of antimicrobial resistance demands the discovery of antibacterial agents with unprecedented chemical scaffolds. Natural products have historically been the most prolific source of antibiotics, yet the vast majority of catalogued natural products remain unte...

The Infinite Volume Limit of the Hopfield Neural Networks in the Replica-Symmetric Regime

Abstract Despite extensive research over the past five decades, a rigorous determination of the infinite volume limit of the free energy of the Hopfield model with an extensive number of patterns has remained an outstanding open problem as standard methods from spin glass theory...

Hardware‐Native Gaussian Sampling With Probabilistic Ising Machines for Modern Communication Paradigms

ABSTRACT Modern communication systems increasingly shift computation to edge devices, where post quantum signing, generative AI and semantic communication must operate under strict energy, latency and memory constraints. A central bottleneck in these workloads is Gaussian samplin...

On the Fragility of Burnt Osteological Fragments: Technical Assessment of Potential Loss of Material

ABSTRACT The analysis of burnt osteological fragments from archaeological and forensic contexts is a challenging area of research due to the fragmentary and often incomplete nature of these remains. Conservation and preservation are ongoing issues, since the thermally altered bon...

The adapted version of the volunteer function inventory to assess the community perspective of volunteer motivation

Psychological inquiry on volunteerism has widely implemented self-part studies on volunteers’ motivations via the Volunteer Function Inventory (VFI). The literature in psychology also has widely acknowledged the limitations of the self-report assessment and the need for clarifica...

Characterizing End-User Auditing of Recommender System Behaviors Affecting Music Discoverability: a Diary Study

Recommender systems shape what people encounter online, yet their role in facilitating or constraining music discoverability is rarely examined from the listener’s perspective. To help address this gap, we present a two-week diary study with nine Italian young adults who reported...