Northwestern University

Gold‐Stabilized Copper Enables Anodic Hydrogen Evolution for Ultralow‐Voltage CO‐to‐Ethylene Electrolysis

ABSTRACT Electrochemical upgrading from CO 2 and CO to ethylene has typically been coupled with the oxygen evolution reaction (OER), whose high standard reduction potential leads to full‐cell voltages above 2.2 V at 200 mA/cm 2 . Here we explored an alternative anodic reaction, w...

The RNA helicase domain of NAT10 promotes the biogenesis of hypomodified ribosomes to enhance cancer cell proliferation

Abstract N-acetyltransferase 10 (NAT10) is a multifunctional enzyme that harbors RNA acetyltransferase and RNA helicase domains and has emerged as a therapeutic vulnerability in solid and hematological malignancies. By coupling Proteolysis Targeting Chimera-mediated degradation o...

Bridging Practice and Publication: Reexamining Quality Improvement in Pediatric Scholarship

Quality improvement (QI) publication rates in pediatrics surged through the early 21st century yet have noticeably plateaued since that time, a paradoxical shift given the volume of ongoing improvement work across pediatric health systems. We propose that the gap lies not in the...

Aflibercept 8 mg in neovascular age-related macular degeneration and diabetic macular oedema: Translating clinical trials into clinical practice

Abstract Provide expert-informed guidance on the integration of aflibercept 8 mg into routine clinical care for patients with neovascular age-related macular degeneration (nAMD) and diabetic macular oedema (DMO), based on clinical trial and real-world evidence. Sixteen retina spe...

Exploration of visual analogue scale versions with the EQ-HWB-9 to measure health, social care, and carer-related quality of life: a VASt landscape

Abstract Purpose Visual analog scales (VAS) serve as brief, informative patient reported outcome measures. The EQ VAS is an important component of EQ-5D instruments but is not currently included in the EQ-HWB-9. This study qualitatively assessed perceptions of alternative VAS con...

Failed metabolic adaptation to stress contributes to epidermal cell adhesion defects in Darier disease

Congenital pathogenic gene variants may not elicit symptoms until later in life, highlighting the importance of identifying extra-genetic factors influencing the onset and severity of heritable diseases. We explored this in Darier disease (DD or ATP2A2 -nEDD), an autosomal domina...

Teaching the Halstead Category Test: A survey of post-doctoral fellowships in adult clinical neuropsychology

The Halstead Category Test (HCT) is considered among the most sensitive measures for detecting global neurological impairment. Although its ability to localize neurological dysfunction or to assess executive function has been questioned, its demonstrated diagnostic sensitivity to...

Review of Particle Physics *

The Review summarizes much of particle physics and cosmology. Using data from previous editions, plus 3,200 new measurements from 903 papers, we list, evaluate, and average measured properties of gauge bosons and the recently discovered Higgs boson, leptons, quarks, mesons, and b...

HeartMate 3 in Pediatric and Complex Populations: Physiologic Rationale, Patient Selection, and Management Strategies

The HeartMate 3 (HM3) left ventricular assist device (LVAD), initially designed for adults, is increasingly utilized in children, small adults, and those with congenital heart disease (CHD), necessitating expanded knowledge and collaborative efforts. This review highlights key ph...

The Financial Burden of Amyotrophic Lateral Sclerosis Diagnosis: Estimating Costs of Unnecessary Procedural Interventions and Exclusionary Testing

Background: People living with amyotrophic lateral sclerosis (ALS) experience diagnostic delays, involving multiple visits to neurologists and non-neurologist specialists. During this process, patients may be misdiagnosed and undergo unnecessary procedures. Additionally, ALS diag...

Within-Person Sweat Chloride Variability in People with Cystic Fibrosis Measured via Wearable Microfluidic Sticker

Melissa H Ross, Thaddeus Cybulski, Rachel S Nelson, Roozbeh Ghaffari, John A Rogers, A J Aranyosi, Garett J Griffith, Daniel M Corcos, Manu Jain; Within-Pe

LGBTQ+ Youth Sexual Orientation and Gender Identity Support in Schools

Abstract LGBTQ+ youth continue to report significant challenges to their wellbeing in schools (e.g., bullying, lack of representation in staff and curricula, and discrimination). The current study employed a large, diverse sample of LGBTQ+ youth to explore the types of support th...

Sleep loss as a cardiometabolic risk factor: a narrative review of clinical and public health implications

Abstract Purpose To synthesize current evidence on how sleep deprivation, impaired sleep architecture, and circadian misalignment affect cardiovascular and metabolic regulation across autonomic, hormonal, inflammatory, and behavioral pathways, and to highlight remaining research...

Associations of Fatherhood and Race With Cardiovascular Health Among Men: Findings From the Coronary Artery Risk Development in Young Adults (CARDIA) Study, 1985‒2022, United States.

. 2026;116(8):1146-1155. https://doi.org/10.2105/AJPH.2026.308439).

Novel Placental Functional Capacity Score: A Single Quantitative Score Estimating Placental Function and Its Association with Pregnancy Outcomes

BACKGROUND: Determining placental functional capacity from a typical pathology report can be difficult. Our goal was to create a new way to report on the functional capacity of the placenta, using much of the typical information obtained in a routine placental pathology assessmen...

Implementation strategies and adjunctive interventions for HIV testing and linkage-to-care in the United States: a systematic review

Ending the HIV Epidemic in the United States depends on expanding HIV testing and rapidly linking people to care. However, methods to improve testing and linkage-to-care are inconsistently described and often conflate health system–level implementation strategies with recipient-d...