Northwestern University

Guided Toward Equity: Communities of Practice and Organizational Change in Community Colleges

ABSTRACT Although community colleges advance equity by providing opportunities for marginalized students to pursue higher education, barriers to earning credentials remain, particularly for students of color. Higher education stakeholders are investing in “equity work” as organiz...

Social media use and depression across 11 years of U.S. adult data

Controversy surrounds the relationship between social media use and depression. Prior research has relied on single datasets, narrower age groups or broad measures of screen time, leaving uncertainty about whether associations of social media use and depression were stable across...

A memorial tribute to Dr. Asgerally T. Fazleabas

Gregory W Burns, Yong Song, J Julie Kim; A memorial tribute to Dr. Asgerally T. Fazleabas, Biology of Reproduction, , ioag180, https://doi.org/10.1093/biol

Little Red Dots host Black Hole Stars: A unified family of gas-reddened AGN revealed by JWST/NIRSpec spectroscopy

Abstract We construct and characterise a sample of 146 little red dots (LRDs) across 2.0 < z < 9.3, selecting all sources with v-shaped UV-optical continua from JWST NIRSpec/PRISM spectra and compact morphologies in NIRCam/F444W imaging. We show that LRD continuum spectra are wel...

Two-Year-Old Girl With Chronic Cough and Lymphadenopathy

A 27-month-old previously healthy girl presented with 3 months of cough and 1 day of fever and rhinorrhea. Her parents had immigrated from Africa, but our patient had been born in the United States and had no notable environmental exposures. An alarming chest radiograph suggested...

Efficacy and Safety of Time-Restricted Eating in Adults With Type 1 Diabetes: A Randomized Controlled Trial

OBJECTIVE: Many adults with type 1 diabetes (T1D) have overweight or obesity, underscoring the need for effective dietary weight loss strategies in this population. Time-restricted eating (TRE) has emerged as a popular approach for weight loss; however, its efficacy and safety in...

Agreement and Performance of Intermittent and Continuous Vital Signs in Critically Ill Children

BACKGROUND: Intermittent vital sign (VS) documentation is the standard of care in pediatric wards and pediatric intensive care units (PICUs). However, intermittent capture of VS values may miss important trajectories and extreme values, particularly for patients at risk of organ...

Isolated Diastolic Hypertension and Cardiovascular Disease Risk in Young Adults

BACKGROUND: Whether isolated diastolic hypertension (IDH) in young adults represents a benign, age-specific phenotype or confers increased cardiovascular disease risk remains uncertain. We assessed the associations between hypertension subtypes, IDH, isolated systolic hypertensio...

Laser Interstitial Thermal Therapy for Brain Tumors: A Prospective Multicenter Analysis of Patients From the LAANTERN Study

Background: Laser interstitial thermal therapy is a surgical tool used to ablate brain tumors, radiation necrosis, and epileptic foci. Data from the completed LAANTERN prospective multicenter registry (NCT02392078), containing tumor patients enrolled in the study across 25 US cen...

Awake Blue Laser Excision and Balloon Dilation of Oropharyngeal Stenosis in High‐Risk Patients

Oropharyngeal stenosis is a rare condition that can develop following head and neck cancer treatment, leading to progressive dyspnea, dysphagia, and dysphonia. Patients with symptomatic dyspnea may benefit from endoscopic surgery. However, head and neck cancer survivors can have...

Trajectories of physical activity and screen media use in toddlers and related parenting practices: Child and Mother Physical Activity Study (CAMPAS)

<title>Abstract</title> <bold>Background:</bold> Physical activity (PA) and screen media use are key behaviors for healthy development in early childhood. This study aimed to investigate 12-month trajectories of PA and screen time among toddlers and examine their associations wit...

Examining smartphone-assessed executive function metrics and intrinsic resting-state functional connectivity in depression

<title>Abstract</title> Major Depressive Disorder (MDD) is a common and costly mental health condition that is often associated with deficits in executive function. Smartphone applications (“apps”) have emerged as promising methods for assessing mental health-related outcomes in...

Ligand-tuned extracellular domain dynamics are correlated with signaling states in an adhesion GPCR

Adhesion G protein–coupled receptors (aGPCRs) transduce signals via engagement of their large extracellular regions (ECRs) with adhesion partners. ADGRG6 (GPR126) is an aGPCR vital for the development of multiple organs and myelination. ECR conformational dynamics of ADGRG6 has b...

The Role of Dopaminergic Agonists in Geographic Atrophy: Converging Evidence From Clinical and Experimental Data

Purpose: Levodopa (L-DOPA) is an emerging drug repurposing candidate for age-related macular degeneration (AMD). Basic and clinical studies identify a potential role for L-DOPA to prevent and treat neovascular AMD. However, only one prior study has been performed in geographic at...

Accessible Complexity Bounds for Restarted PDHG on Linear Programs with a Unique Optimizer

The restarted primal-dual hybrid gradient method (rPDHG) has recently emerged as an important tool for solving large-scale linear programs (LPs). For LPs with unique optima, we present an iteration bound of [Formula: see text], where [Formula: see text] is the target tolerance, [...

Cranio-orbital craniotomy via an eyebrow incision for resection of anterior clinoid and tuberculum sella meningiomas

Abstract Background Anterior clinoid meningiomas (ACM) and tuberculum sella meningiomas (TSM) are anterior skull base tumors that commonly cause visual deterioration. The supraorbital keyhole approach may be used to resect these tumors but is limited by restricted intraoperative...

The blood system in Ukraine: Experience in martial law conditions

BACKGROUND/CASE STUDIES: Efficient blood and blood components supply is key to the stable operation of a health care system, especially to a civilian population and military under martial law. The blood system is an important component of a state's defense capability and national...

Cardiac Implantable Electronic Device Infection: Nationwide Trends in Extraction Utilization and In‐Hospital Outcomes

INTRODUCTION: Contemporary, real-world adherence to guideline-directed transvenous cardiac implantable electronic device (CIED) extraction for patients with CIED infections in the US remains incompletely characterized. As such, we sought to evaluate national trends in CIED extrac...

Four Lenses Toward Principle-Based Understanding of Granular Segregation in Dense Flows: Particle, Continuum, Statistical, and Conceptual Approaches

Abstract This review examines the development of concepts and models describing the spontaneous spatial separation—segregation—of dense flowing granular mixtures. Although particle-scale interactions are largely understood and modern discrete element methods can resolve system dy...

Association between clinician team structure and continuous pulse oximetry overuse among infants hospitalized with bronchiolitis: An Eliminating Monitor Overuse Trial substudy

Abstract Continuous pulse oximetry (cSpO 2 ) monitoring for hospitalized children with bronchiolitis not requiring supplemental oxygen is an established form of medical overuse. We examined whether clinician team structure influences cSpO 2 overuse. In this secondary analysis of...