McGill University

Sleep quality is associated with gut microbiome signatures of hyperuricemia in Chinese elderly adults: a community-based case–control study

Hyperuricemia (HUA) has become a global health issue due to its rapidly increasing prevalence. Growing evidence from population and animal studies suggests that gut microbial dysbiosis and lifestyle changes are involved in serum uric acid metabolism. However, most existing studie...

What works in transdiagnostic adult psychiatric day treatment programs? A scoping review of common components contributing to improved mental health outcomes

Background Day Treatment Programs (DTPs) provide intensive, multidisciplinary, non-residential care for adults with acute or complex mental illness. Despite their long-standing role as recovery-oriented alternatives to inpatient admission, contemporary DTPs vary widely in structu...

Sex Disparity in Enrolment to Clinical Trials for Onchocerciasis and Trachoma

To determine whether female enrolment in randomized interventional clinical trials for onchocerciasis and trachoma reflects the real-world sex distribution of disease burden, and to evaluate sex-based differences across trial characteristics. We performed a cross-sectional analys...

From Awareness to Action: Co‐Designing Culturally Safe and Equitable Rehabilitation in Canada – Protocol for the Two‐Phase Ireach Qualitative Study

ABSTRACT Background Inequities in access, engagement, and outcomes persist across outpatient rehabilitation services in Canada, disproportionately affecting Indigenous Peoples, newcomers and refugees, gender‐ and sexually‐diverse individuals, and people with lower income. Althoug...

Proteomic profiling of the Pseudomonas aeruginosa stringent response highlights global adaptive responses during stationary phase

ABSTRACT Pseudomonas aeruginosa ( P.a ) is a clinically important opportunistic pathogen capable of adapting and surviving a wide range of environments and stress conditions. A central regulator of this adaptability is the stringent response, mediated by the alarmones (p)ppGpp. A...

A systematic interactome of Saccharomyces cerevisiae SET1C expands its functional landscape and identifies candidate regulatory connections

Set1 is the catalytic subunit of SET1C or COMPASS, which methylates histone H3K4 and serves as a scaffold for the association of seven tightly bound polypeptides. We have employed yeast two-hybrid screenings to determine the interactome of Set1 and each subunit, providing a uniqu...

Infrequent Resolving Algorithm for Online Linear Programming

Online linear programming (OLP) has gained significant attention from both researchers and practitioners because of its extensive applications such as online auctions, network revenue management, order fulfillment, and advertising. Existing OLP algorithms fall into two categories...

Breaking the phase noise–mode purity trade-off in long-loop OEOs via cascaded zero-dispersion recirculating loops

Abstract Optoelectronic oscillators (OEOs) generate microwave signals with ultra-low phase noise by incorporating long optical fiber loops as high-Q energy storage elements. However, long fiber loops reduce the free spectral range, leading to dense oscillation modes and requiring...

Navigating wastewater management policy and practice in Canada: A North-South perspective

Population and economic growth are increasing municipal wastewater volumes in Canada and the associated risks to surface water, groundwater, ecosystems, and public health. Under the Wastewater Systems Effluent Regulations (WSER), Canada sets federal minimum discharge standards fo...

SPEF1 mediates assembly of central pair microtubule complexes in cilia of Tetrahymena

SPEF1 is a conserved calponin-homology domain protein that decorates the seam of central pair microtubules in the distal segment of motile cilia. Here, we show that in the ciliate Tetrahymena, loss of SPEF1 disrupts the central pair throughout the middle segment, which comprises...

Incidence, Risk Factors and Management of Adverse Events in Contemporary Real‐World Care of Children with Juvenile Idiopathic Arthritis

OBJECTIVE: We describe the frequency, risk factors, severity, and management of actionable and serious adverse events (AAE and SAE) in children with newly diagnosed Juvenile Idiopathic Arthritis (JIA) in Canada. METHODS: We enrolled patients within 3 months of JIA diagnosis in th...

Acceptability of My Ten: a physical activity intervention for family caregivers of people with advanced cancer

Abstract Background The caregiving experience can have a significant impact on family caregivers’ (caregivers) health and well-being, particularly those of patients with advanced cancer. Interventions to support caregivers through health-promoting strategies are needed. The physi...

Respiratory Syncytial Virus–Related Hospitalizations Among Infants Receiving Nirsevimab

Importance Respiratory syncytial virus (RSV) is a leading cause of hospitalization among infants. Nirsevimab, a long-acting monoclonal antibody that protects against severe RSV, was publicly funded for all infants in the Canadian provinces of Ontario and Quebec starting in the fa...

Specialized Textiles Association

We have built a Playlist Videos from Youtube for Specialized Textiles Association. Some factories are concerned : H&M Foundation, Winners, etc

Specialized Textiles Association

We have built a Playlist Videos from Youtube for Specialized Textiles Association. Some factories are concerned : H&M Foundation, Winners, etc

Emotion Regulation in Response to Stress in the Daily Lives of Women With and Without Eating Disorders: An Ecological Momentary Assessment Study

ABSTRACT Objective Emotion regulation difficulties are known risk/maintenance factors for eating disorders (EDs). Few studies have investigated use of adaptive/maladaptive emotion regulation strategies in people with EDs, especially using ecologically valid data. This study: (1)...

Conference Goals And Learning Preferences Among Attendees at A National Surgical Meeting

Objective This study evaluated differences in conference goals and preferred learning modalities across demographic groups at a national surgical conference. Design An optional online survey collected demographic information (gender, practice type, role, years in independent prac...

Balancing data quality and participant burden: a comparative analysis of abbreviated vs extended symptom diaries in the CanTreatCOVID trial

Abstract Background Symptom diaries are widely used in acute respiratory infection trials to capture patient-reported symptom severity and recovery. Longer questionnaires may provide a more complete clinical picture but can increase participant burden and reduce adherence. Eviden...

Sex & Gender Science: integrating the social with the biological

Abstract For decades, researchers have largely studied aspects of sex and gender separately; the former as a basic science and the latter as a social construct with real world consequences, including health inequities. In recent years, as our collective understanding of how the b...

Computer-Assisted Proofs for Geometry Optimization: From Crystallization to Carbon Nanotubes

Abstract. We present a framework based on computer-assisted proofs that turns geometry optimization simulations for atomistic structures into mathematical proofs. Starting from a numerically computed approximation of a local minimizer or saddle point, we use validated numerical c...