Management of Type 2 Diabetes, 2026. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
Abstract
The American Diabetes Association and the European Association for the Study of Diabetes convened a panel to update the consensus statement on the management of type 2 diabetes in nonpregnant adults, published since 2006 and last updated in 2022. The target audience is the multidisciplinary health care team providing diabetes care in the U.S. and Europe. A systematic examination of publications since 2022 informed new recommendations. This update has broadened the focus from the management of hyperglycemia to the holistic management of type 2 diabetes and its risk of associated multiple long-term conditions. Fundamental aspects of diabetes care include promoting healthy lifestyle behaviors (healthy eating, 24-h physical behaviors including sleep, and avoiding tobacco and substance use), alongside the provision of psychological support and weight management interventions. For the management of people living with type 2 diabetes, earlier use, potentially from diagnosis, of sodium-glucose cotransporter 2 (SGLT2) inhibitors and/or glucagon-like peptide 1 (GLP-1)-based therapies to offer organ protection and improve long-term outcomes in type 2 diabetes is advocated. Furthermore, earlier combination use of SGLT2 inhibitors and GLP-1-based therapies should be considered in people with concomitant cardiovascular disease, chronic kidney disease, and heart failure. Finally, the ability to transform outcomes for people living with type 2 diabetes is within our grasp through the consistent, equitable, and systematic implementation of strategies and therapies that are already available.
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Authors: Melanie Jane Davies, Vanita R. Aroda, Mandeep Bajaj, Nuha A. ElSayed, Francesco Giorgino, Jennifer Green, Rita Rastogi Kalyani, Nisa M. Maruthur, Chantal Mathieu, Sylvia E. Rosas, Peter Rossing, Tommy Slater, Tsvetalina Tankova, Pinar Topsever, Απόστολος Τσάπας, John B. Buse
Institutions: University of Bari Aldo Moro, Brigham and Women's Hospital, University of Maryland, Baltimore, Johns Hopkins University, University of North Carolina at Chapel Hill, University of Copenhagen, Hippocration General Hospital, Johns Hopkins Medicine, Universitair Ziekenhuis Leuven, Aristotle University of Thessaloniki, Baylor College of Medicine, Kent Hastanesi, Medical University of Sofia, University Hospitals of Leicester NHS Trust, University of Maryland Medical Center Midtown Campus, Clinical Research Institute, Joslin Diabetes Center, Leicester General Hospital, Ippokrateio General Hospital of Thessaloniki, Ford Foundation, American Diabetes Association, Steno Diabetes Center Copenhagen