Ippokrateio General Hospital of Thessaloniki

Candidozyma auris Prosthetic Joint Infection: A Case Report and Systematic Case-Based Literature Review of Osteoarticular Infections

Candidozyma auris, recently taxonomically reclassified, represents an emerging multidrug-resistant fungal pathogen that has evolved into a critical nosocomial and global public health threat. This organism exhibits a profound capacity for resilient biofilm formation on biotic and...

Management of Type 2 Diabetes, 2026. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)

The American Diabetes Association and the European Association for the Study of Diabetes convened a panel to update the consensus statement on the management of type 2 diabetes in nonpregnant adults, published since 2006 and last updated in 2022. The target audience is the multid...

Effectiveness of early initiation of idursulfase in infants and very young children with mucopolysaccharidosis II: a retrospective chart review in siblings

Introduction Enzyme replacement therapy (ERT) with intravenous idursulfase is the standard of care for patients with mucopolysaccharidosis II (MPS II; Hunter syndrome). Data are limited for children aged ≤12 months. This retrospective study evaluated outcomes with early ERT. Meth...

Nonfatal Burden of Disease and Risk-Attributable Burden in Romania, 1990 to 2023: A Secondary Analysis of Global Burden of Disease 2023 Estimates

Background/Objectives: We assessed changes in nonfatal disease burden and risk attribution in Romania between 1990 and 2023. Methods: We analysed Global Burden of Disease (GBD) 2023 estimates of years lived with disability (YLDs), related nonfatal measures and risk attribution fo...

A Review of Proteomic Studies in Uterine Leiomyosarcoma: Biomarkers, Pathways, and Clinical Potential

Uterine leiomyosarcoma (uLMS) is a rare but highly aggressive mesenchymal malignancy of smooth-muscle origin that represents a significant therapeutic challenge due to its poor prognosis and limited treatment options. Despite advances in molecular characterization, diagnosis rema...

Prediction of atrial fibrillation recurrence before catheter ablation using P-wave ECG features: simplicity of random forest versus CNN in small datasets

Atrial fibrillation (AF) is an arrhythmia affecting 3% of the general population. Transcatheter ablation (CA) is the most effective treatment option for patients with AF; however, recurrence rates remain high. Early classification of patients based on pre-ablation data could help...

Associations between physical activity levels and self-perceived quality of life and well-being in hemodialysis patients and their informal caregivers: a multicenter cross-sectional study

BACKGROUND: This study aimed to investigate the associations between the physical activity of hemodialysis (HD) patients and their informal caregivers and measures of their well-being and quality of life (QoL). METHODS: This multi-center cross-sectional study included one hundred...

Contribution to Diagnostic Accuracy and Prognostic Significance of MicroRNAs in Thyroid Cancer

The incidence of thyroid cancer, the most common endocrine malignancy, has increased significantly, underscoring the need for improved diagnostic and prognostic methods. MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate gene expression and play vital roles in ca...

Patterns and phenotypes of enhanced recovery after surgery implementation in gynaecological oncology: A latent class analysis

Objective: Enhanced recovery after surgery protocols are widely recommended, yet their real-world implementation remains inconsistent due to multiple barriers. This study aimed to characterise implementation patterns during early enhanced recovery after surgery adoption. Methods:...