University of Washington

Intimate partner violence against Jordanian women: a systematic review of prevalence, associated factors, and health outcomes

Intimate partner violence (IPV) is a pervasive public health problem in many countries, including Jordan. To our knowledge, no systematic reviews have been conducted in Jordan regarding the prevalence of IPV, its associated factors, and related health outcomes. This systematic re...

Dams trigger long-term river-floodplain decoupling in dynamic Andean foreland rivers

Andean foreland rivers are preferential sites for ongoing and planned hydroelectric dam construction in the Amazon Basin. These rivers are characterized by high sediment fluxes that drive rapid rates of channel migration, large river-floodplain sediment exchanges, and creatediver...

Identifying Orbit Lengths for Promotion

In this work we study Schützenberger's promotion operator on standard Young tableaux via a corresponding graphical construction known as $m-$diagrams. In particular, we prove that certain internal structures of SYT are preserved under promotion and correspond to distinct componen...

Wasserstein mirror gradient flow as the limit of the Sinkhorn algorithm

We prove that the sequence of marginals obtained from the iterations of the Sinkhorn algorithm or the iterative proportional fitting procedure (IPFP) on joint densities, converges to an absolutely continuous curve on the 2-Wasserstein space, as the regularization parameter ε goes...

Substance use treatment utilization and unmet demand among recently incarcerated syringe services program participants in Washington state

People who use drugs are disproportionately impacted by incarceration and face elevated overdose risk following release. Despite this heightened risk, access to evidence-based substance use disorder (SUD) treatment—particularly medications for opioid use disorder (MOUD)—remains l...

De novo design of RNA pseudoknots with deep learning

RNA design has been hindered by the limited accuracy of 3D structure prediction. Here, we show that intricate RNA structures can be generated with current deep learning tools through accurate de novo design of pseudoknot secondary structures. In an Eterna competition involving 57...

Preserved Through Hyperaridity, 150 Million Years of Exhumation and Strike‐Slip Deformation in the Atacama Coastal Cordillera

Abstract The Coastal Cordillera of northern Chile, in the forearc of the Andean subduction zone, provides an ideal site to evaluate exhumation above the oldest active subduction under extreme aridity. This range lies parallel to a sediment‐starved trench, has experienced hyperari...

Impact of Dapagliflozin on MRI ‐Derived Epicardial Adipose Tissue: Secondary Imaging Analysis of a Randomized Trial

BACKGROUND: Epicardial adipose tissue (EAT) is a metabolically active fat depot associated with cardiovascular risk and represents a modifiable imaging biomarker. Studies have shown that sodium-glucose cotransporter-2 (SGLT2) inhibitors reduce EAT thickness in patients with type...

Sequential restriction of SNARE-mediated fusion by the COPII inner coat and SNARE chaperones

Abstract SNARE-mediated fusion requires assembly of four SNARE domains (R, Qa, Qb, and Qc) distributed across two membranes, with an SM (Sec1/Munc-18 family) chaperone catalyzing this assembly. We investigated topological requirements for the four SNAREs that mediate ER-Golgi fus...

Utility of DAT in Low-Risk Neonates with ABO or RhD Incompatibility

BACKGROUND Routine direct antiglobulin test (DAT) screening in newborns at risk of isoimmune hemolytic disease is a long-standing practice. Advancements in prophylactic care and noninvasive hyperbilirubinemia monitoring warrant reevaluating the value of DAT. We investigated the c...

A Surgical Algorithm for Upper Cervical Trauma Based on the AO Spine Upper Cervical Injury Classification System

Study Design. Global cross-sectional survey Objective. To establish a surgical algorithm for upper cervical spine injuries using the AO Spine Upper Cervical Injury Classification (UCIC) system, defining operative thresholds using a novel proposed Upper Cervical AO-Spine Injury Sc...

Schools’ Respect for Identity-Based Differences and Student Outcomes: Examining the Relationship among Students with Varying Numbers of Marginalized Identities

When schools value diversity, students with marginalized identities exhibit better academic and well-being outcomes. However, most work focuses on one identity dimension (e.g., race, sexuality) at a time. Using data from the California Healthy Kids Survey (N=205,064 6th–12th grad...

An Umbrella Review of Artificial Intelligence Applications in Mental Health Care

BACKGROUND: Artificial intelligence (AI) is increasingly used in mental health care to address rising demand, workforce shortages and access barriers; however, evidence remains scattered across multiple systematic reviews, limiting synthesis and practical application. OBJECTIVE:...

The impact and evolution of environmental/occupational, behavioural, and metabolic risk factors on CVD burdens in the Asia–Pacific region from 1990 to 2023: a secondary analysis of the Global Burden of Disease Study 2023

Background Understanding epidemiological trends of the cardiovascular risk factors is integral in designing effective countermeasures in tackling cardiovascular diseases (CVD) in the Asia–Pacific. The study aims to examine the cardiovascular risk factor burden in the Asia–Pacific...

Leveraging Data‐Driven and Fundamental Insights for Electrolyte Innovation in Lithium Metal Batteries

ABSTRACT The rise of data science and decades of accumulated battery research have paved the way for the general use of computing in research. Here, the largest experimental coulombic efficiency (CE) dataset curated from over 100 scientific articles under strict selection criteri...

Distinguishing between clinical interventions and implementation strategies in trials

Abstract Background Trialists sometimes find it difficult to determine whether the innovation they are evaluating is a clinical intervention or an implementation strategy. The inaccurate classification of innovations can lead to negative consequences such as the misspecification...

Multi-stakeholder perspectives on acceptability and delivery of buprenorphine for women who use drugs

Women who use drugs (WWUD) face substantial barriers to accessing medications for opioid use disorder (MOUD), including buprenorphine. As part of a formative evaluation to co-design a community-based intervention for MOUD delivery, we explored multi-stakeholder perspectives on th...

Resampling Fragility, Perturbation Fragility, and Why the Global Fragility Index Is Not a P-Value in Disguise

The charge that the fragility index is a P-value in disguise rests on a strong correlation between the two across trials, and it overlooks a distinction between two distinct constructs derived from the same observed result. Resampling fragility asks how often the significance ver...

Survival of the Flattest: Teams with Low (But Not High) Status Differentiation Turn Failure into Success by Adding High-Status Members

Most prior research on teams’ responses to failure treats teams as closed systems. However, after failures, teams may seek to improve performance by bringing in new members. Adopting a teams-as-open-systems perspective, we test which teams are more willing to add high-status memb...

Assessing the need for reproductive genetic counseling among adults with cystic fibrosis

Abstract Background Reproductive health has become an increasingly important focus for people with cystic fibrosis (CF), and guidelines have recommended routine inclusion of genetic counselors on care teams to address questions regarding infertility, pregnancy planning, prenatal...