University of Washington

Cross-platformization: How U.S. right-leaning media curate their posts on Twitter and Truth Social

This study examines how seven right-leaning media organizations utilize cross-platformization strategies to reach audiences across multiple platforms; in this case, Twitter and Truth Social. Focusing on both content volume and story packaging, we collect right-leaning media organ...

Humans: Intertwined with life and the basic elements in the Anthropocene biosphere

Abstract The notion of people and nature as intertwined and embedded in the biosphere is gaining traction in contemporary scientific discourses. But what does it mean for a human being to be intertwined? Here, we explore this question through two lenses: looking at the human body...

Communication Challenges and Strategies in Adolescent and Young Adult Cancer Survivorship Care: A Qualitative Study of Clinician Perspectives

Purpose: Adolescent and young adult (AYA) cancer survivors treated in pediatric settings face long-term physical and psychosocial effects from cancer treatment, and lifelong specialized survivorship care is recommended. Prior research has focused on what survivors need to know ab...

Hydrothermal Modification of Porous Silica Microbands Improves Single-Cell Assays of the Ether-Lipid Metabolism

Abstract The ability to separate and detect lipid metabolites in single cells has been achieved using a miniaturized thin-layer chromatography (TLC) platform termed picoTLC (pTLC). However, continued innovations in the matrix fabrication, lipid reporter development, and single-ce...

Bifunctional Phagocytic Synapse Enhancers Remodel the Tumor Microenvironment to Overcome Immunosuppression

Abstract Current immunotherapies often fail in immunologically “cold”, macrophage-rich tumor microenvironments (TMEs). Multi-targeting approaches that modulate innate-adaptive immune activation represent a promising frontier in cancer immunotherapy. Here, we developed phagocytic...

Bridging the gap in Long COVID care: identifying core competencies for primary care curriculum development and evaluation

Abstract Background There is an unmet need for Long COVID care within our healthcare system. Primary care clinicians (PCPs) face challenges in providing effective care due to limited relevant Long COVID training and lack of standardized clinical resources. Pre-CME (continuing med...

HIV Testing and Care Among Publicly Insured Enrollees With Schizophrenia: Is There a Benefit to Dual Eligibility?

Background Patients with schizophrenia experience gaps in the human immunodeficiency virus (HIV) care continuum. We examined the impact of dual enrollment in Medicare upon HIV testing and retention among Medicaid‐enrolled patients with schizophrenia. Methods Using Medicaid Analyt...

Needle in a Forest: Searching for Thresholds to Maximize Coexistence Between People and Wildlife in a Remote Wilderness Park

Managers of protected areas are charged with providing public access and enjoyment while minimizing wildlife disturbance, a difficult feat given that wild animals often respond to humans as predators. Evaluating the effects of people on wildlife is critical to inform management a...

Omic risk scores are associated with COPD-related traits across three cohorts

Background: Chronic obstructive pulmonary disease (COPD) exhibits marked heterogeneity in lung function decline, mortality, exacerbations, and other disease-related outcomes. Omic risk scores (ORS) estimate the cumulative contribution of omics, such as the transcriptome, proteome...

NLTS Hamiltonians from Good Quantum Codes

Abstract. The no low-energy trivial state (NLTS) conjecture of Freedman and Hastings [ Quantum Inf. Comput., 14 (2014), pp. 144–180] posits that there exist families of Hamiltonians with all low energy states of nontrivial complexity (with complexity measured by the quantum circu...

Early Childhood Services for Transfronterizx Families of Autistic Children: Perspectives From Community Providers

In this qualitative study, we investigated the perspectives of early childhood service (ECS) providers on the facilitators and barriers faced by transfronterizx caregivers of autistic children in the U.S.-Mexico border. We applied thematic analysis to focus groups using the socio...

Uneven TCR chain pairing constraints govern epitope recognition

Combinatorial pairing of independently recombined T cell receptor (TCR) α- and β-chains is central to diversifying the TCR repertoire. Although sequence motifs in one chain correlate with epitope recognition, the extent to which a single chain dictates specificity remains unclear...

Initial Z-Drug Prescription Duration and Long-Term Use

This cohort study evaluates the association between the days’ supply of an initial Z-drug prescription and subsequent long-term use.

Early Radiographic Changes Predict Radiographic Stability in Distal Radius Fractures: Development and Validation of an Explainable Predictive Model

Purpose To determine whether early radiographic trajectory data can predict the timing of stability in conservatively managed distal radius fractures (DRFs) and to identify which clinical and radiographic features most influence stabilization timing. Methods This retrospective co...

The gerotherapeutic drugs rapamycin, acarbose, and phenylbutyrate extend lifespan and enhance healthy aging in house crickets

Abstract The house cricket ( Acheta domesticus ) is a promising preclinical geroscience model due to its short lifespan, low maintenance, age-associated functional decline, and responsiveness to geroprotective drugs. Continuous dosing with rapamycin, acarbose, and phenylbutyrate...

Impact of Omitting Observation-Status Data on Hospital Readmission Metric for Pediatric Care

OBJECTIVES: Literature from Medicare beneficiaries suggests that hospital readmission metrics limited to inpatient encounters, omitting observation-status data, may not fully capture hospital performance and affect rankings. The impact of omitting observation-status data on this...

Accountability, Integrity: AI Policy in Public Libraries

As artificial intelligence reshapes both library work and the information environment, public libraries must determine whether or how to engage with AI while maintaining library values. To our knowledge, there exists no published analysis of how American and Canadian public libra...

Challenging the Boundaries: Early Modern Women Writing About Earthly Love

This essay considers the social and cultural challenges faced by lower-class women in sixteenth-century Italy who wished to be taken seriously as literary figures, as exemplified by Gaspara Stampa and Isabella Andreini. Both women were poets who wrote about earthly love in their...

Superlarge-Bore Versus Large-Bore Aspiration Catheters in Mechanical Thrombectomy: A Multicenter Propensity-Matched Analysis

BACKGROUND AND OBJECTIVES: Aspiration catheters are an integral component of mechanical thrombectomy for acute ischemic stroke (AIS). Following early series demonstrating increasing procedural efficiency and improved outcomes with use of large-bore (LB) aspiration catheters, ther...

Centering youth voices: youth satisfaction and disparities in Illinois child welfare residential care

Youth in child welfare residential care present with complex needs and strengths; systematic efforts are needed to improve their treatment. Youths’ perspectives are critical to these efforts. This study explores data from Likert-scale satisfaction surveys of youth receiving resid...