University of Toronto

Video reconstruction of variable VLBI observations with neural fields

Abstract Supermassive black hole accretion and the ejection of collimated, relativistic jets of plasma are intrinsically dynamic processes shaped by large-scale magnetic fields 1–4 . Various algorithms have been developed to image these objects at different scales using radio int...

Prospective validation of a non-invasive bedside protocol for tracheostomy decannulation in acquired brain injury with otolaryngologic concordance

Decannulation of tracheostomy in individuals with acquired brain injury (ABI) is challenging and often requires endoscopic airway assessment. A reliable noninvasive bedside protocol could support decision-making in neurorehabilitation settings. We conducted a prospective observat...

Adapting computerised language sample analysis for Jamaican Creole-Jamaican English-speaking preschoolers: A pilot study

This pilot study examines the feasibility of adapting the Systematic Analysis of Language Transcripts (SALT) for Jamaican Creole-Jamaican English-speaking preschoolers. Standard SALT protocols, designed for monolingual English speakers, risk misrepresenting bilingual children's l...

Pregnancy after Hemithyroidectomy: Increased Risk of Gestational Overt Hypothyroidism Despite Favorable Obstetric Outcomes: A Nationwide Study

Background: To assess the association between preconception hemithyroidectomy and the risk of gestational hypothyroidism and obstetric outcomes. Methods: This nationwide population-based retrospective cohort study compared euthyroid pregnant women with a history of hemithyroidect...

Site-specific phosphorylation affects the structure and interactions of the Ycf1p R region

Many ATP binding cassette (ABC) proteins function in active transport of solutes across biological membranes. At minimum, ABC proteins are composed of two repeats, each consisting of a transmembrane domain (TMD) and a nucleotide binding domain (NBD). In many ABC proteins, the TMD...

Does Digitalization Widen Labor Income Inequality?

ABSTRACT We develop a growth model that endogenizes the occupational choice of workers with different ability levels to study how digitalization affects labor income inequality. The framework incorporates digitalization's multifaceted effects on the economy: (i) it influences eco...

Identification, validation, and prediction of longitudinal recovery phenotypes in degenerative cervical myelopathy: analysis of prospective cohorts and a randomised controlled trial

Background Symptom evolution in degenerative cervical myelopathy (DCM) is traditionally characterized by severity of neurological deficit. A recent expert consensus challenged this view, proposing that DCM fluctuates across neurological, functional and health-related quality of l...

P1.014. Gastroesophageal Intussusception After Myotomy for Achalasia

Abstract Topic Benign Disease: Esophageal Function and Motility Case Submission Gastroesophageal intussusception (GEI) is a rare condition in adults, defined by telescoping of the stomach into the oesophagus. Its presentation is often nonspecific—manifesting as dysphagia, vomitin...

P1.141. A Machine Learning Model for Assessment of Conduit Perfusion in Robotic Assisted Minimally Invasive Esophagectomy Using Indocyanine Green

Abstract Topic Esophageal Cancer: Other Background Anastomotic leak remains a major complication in esophagectomy. Indocyanine Green (ICG) can assist with the assessment of conduit perfusion but remains subjective and prone to bias. Our lab has worked to design a computer vision...

Programming of deep brain stimulation of the centromedian nucleus of the thalamus for drug‐resistant epilepsy: A meta‐analysis and proposed programming framework

Abstract Objective Although the centromedian nucleus of the thalamus (CM) is an increasingly considered deep brain stimulation (DBS) target for drug‐resistant epilepsy (DRE), there is significant variability in programming practices, which may contribute to heterogenous outcomes....

Little Red Dots host Black Hole Stars: A unified family of gas-reddened AGN revealed by JWST/NIRSpec spectroscopy

Abstract We construct and characterise a sample of 146 little red dots (LRDs) across 2.0 < z < 9.3, selecting all sources with v-shaped UV-optical continua from JWST NIRSpec/PRISM spectra and compact morphologies in NIRCam/F444W imaging. We show that LRD continuum spectra are wel...

Assessing Challenges and Barriers to Effective Wound Care in Rural Indigenous Communities

OBJECTIVE: To explore the lived experiences of patients with chronic wounds from a remote Indigenous community in Northern Manitoba, Canada, focusing on challenges in wound management, the impact on quality of life, barriers to wound care access, and the role of traditional heali...

Revisiting the association between musical expertise and second-language proficiency

Abstract Musical expertise is frequently correlated with second-language (L2) proficiency, but it remains unclear whether this association generalizes across languages and measures. Here, we examined links between musical expertise and L2 proficiency among native speakers of Port...

Joint-RPCA: domain-aware multi-omics integration for systems microbiology

Integrating multi-omics data is essential for microbiome research, as microbial communities are shaped by and respond to interdependent processes, including taxonomic composition, metabolite production and utilization, and gene expression. However, accurately capturing ecosystem-...

Proper Orthogonal Decomposition-based Model-Order Reduction for Smoothed Particle Hydrodynamics Simulation—Mass-Spring-Damper System

Model Order Reduction (MOR) based on Proper Orthogonal Decomposition (POD) and Smooth Particle Hydrodynamics (SPH) has proven effective in various applications. Most MOR methods utilizing POD are implemented within a pure Eulerian framework, while significantly less attention has...

“As soon as it’s trying to be persuasive, my skepticism kicks in”: A qualitative study to co-design vaccine communication strategies with vaccine hesitant adults in Canada

Vaccine hesitancy continues to impede vaccine uptake in Canada. Few interventions directly engage hesitant adults in co-designing communication materials. This study aimed to co-develop and evaluate digital vaccine communication messages with hesitant adults in Canada to improve...

ELSSA: Explainable large language model-based decision support for public transit incident management

Rapid incident response in public transit requires supervisors to make defensible decisions that align with both formal standard operating procedures (SOPs) and practical agency experience recorded in past reports. However, conventional retrieval-augmented generation (RAG) often...

Assortment Optimization for the Multinomial Logit Model with Repeated Customer Interactions

This paper presents the multinomial logit model with repeated customer interactions. In each period, the same customer selects a product from the recommended assortment or opts out. From the seller’s perspective, the choice probability in the current period is updated based on th...

Operationalizing Patient Experience Data as a System Feedback Asset in Learning Health Systems: Learnings From Model of Care Redesign at Trillium Health Partners

ABSTRACT Introduction Learning Health Systems (LHS) offer a pathway to continuously improve care by integrating data and lived experience, yet few practical examples demonstrate how LHS can be operationalized in hospital settings in ways that embed the voices of patients and fami...

Artificial intelligence-enabled analysis of electron micrographs to assess mitochondrial morphology in triple-negative breast cancer

Advancements in transmission electron microscopy (TEM) have enabled in-depth studies of biological specimens, offering new avenues to large-scale imaging experiments with subcellular resolution. Mitochondrial morphology is of growing interest in cancer biology due to its crucial...