University of Cambridge

Polarization-enhanced ultrafast carrier transfer dynamics in Ga2O3/WS2 heterojunctions

Polarization engineering offers a promising strategy to enhance photogenerated carrier separation in van der Waals heterojunctions. Herein, the mechanisms governing polarization-enhanced carrier separation in Ga2O3/WS2 are investigated using nonadiabatic molecular dynamics. The r...

Bonding‐chemistry‐guided design of carbon frameworks for rechargeable‐ion batteries

Abstract Various carbon frameworks are central to rechargeable‐ion batteries, while continuous structural and compositional regulation provides broad opportunities to improve fast‐charging capability, storage capacity, and cycling stability. However, a unified chemistry‐based und...

Gender Bias in Bribe Solicitation: Evidence From Firm–State Interactions

Previous research has shown that women-led businesses are less likely to bribe officials to bypass administrative burdens, assuming that this is because women are less susceptible to corruption. We uncover an additional mechanism that focuses on the beliefs and practices of corru...

Generative AI, Technology and the Ecology of Persistence: A Response to Tække

Jesper Tække’s article addresses a genuine conceptual problem. Rather than treating generative AI as either a continuation of deterministic technology or a newly autopoietic entity, he argues that it is better understood as a form of non-trivial technology whose stochastic operat...

Junctional plakoglobin regulates intestinal epithelial cell proliferation via MAPK/ERK signaling

Junctional plakoglobin (JUP) is a desmosomal protein essential for epithelial tissue integrity and epithelial-immune cell crosstalk. Although JUP has been implicated in inflammatory processes, its role in intestinal epithelial repair remains unclear. In vitro, loss of JUP in Caco...

Positive in-field impacts of regenerative agriculture on ground beetles in arable crop fields

Regenerative agriculture is seen as a potentially viable model for sustainable soil management. While boasting benefits for soil health, effects of regenerative agriculture on farmland biodiversity and ecosystem services remain poorly known. Ground beetles (family Carabidae) are...

A global study of novel agents in paediatric and adolescent relapsed and refractory B-cell non-Hodgkin lymphoma (Glo-BNHL): protocol for an adaptive international platform clinical trial

The second Paediatric Strategy Forum of the international multi-stakeholder organisation, ACCELERATE (Nov-2017), concluded that an international approach to conducting clinical trials in relapsed and refractory paediatric B-cell non-Hodgkin lymphoma (r/r B-NHL) was critical and t...

Near-atomistic simulations reveal the molecular principles that control chromatin structure and phase separation

Abstract Understanding how chromatin’s physicochemical properties shape its emergent organization is central to deciphering genome function. To address this, we present OpenCGChromatin, a high-performance coarse-grained model that achieves near-atomistic simulations of chromatin...

Children, Robots, and Reproducibility: A review of recent reproducibility challenges in child-robot interaction

Given the rapid advancements and shifting requirements in the field of Child-Robot Interaction (CRI), it is crucial to understand how the field is evolving and if and how researchers are adhering to current best practices. We present a review of five years (2020-2024) of CRI rese...

Performance evaluation of validated diagnostic assays for Rift Valley Fever: a systematic review

Accurate diagnosis of Rift Valley Fever (RVF) disease is critical for outbreak surveillance, containment, intervention, trade, and public health. In this study, we sought to review available evidence on characteristics of validated RVF diagnostic assays used in livestock, humans...

Neurodegenerative disease risk associated with gene expression in peripheral monocytes across ancestries

Abstract It is hypothesised that peripheral immune states responding to regional environmental triggers contribute to central neurodegeneration. Region-specific genetic selection pressures require this hypothesis to be assessed in an ancestry-specific manner. Here, we utilise gen...

Engineering neurovascular thrombosis: Light-based bioprinting for patient-specific modeling and women’s cerebrovascular health

Cerebral venous sinus thrombosis (CVST) and carotid web (CW) are distinct cerebrovascular disorders where vascular geometry, disturbed hemodynamics, and endothelial activation interact to drive thrombosis. Both conditions disproportionately affect women, yet remain understudied b...

Three Distinct Binding Modes Govern High-Affinity Ligand Interactions with Amyloid Fibrils

Abstract Fibrillar protein aggregates are a defining feature of neurodegenerative diseases and represent attractive biomarkers and therapeutic targets. However, the rational design of small-molecule ligands and probes targeting these aggregates is limited by a poor understanding...

Love or Law: Viking Foundations of Medieval English Dispute Settlement

Abstract In prominent legal historical works, Michael Clanchy and Stephen D. White constructed an important paradigm for medieval dispute settlement by adapting the phrase “law and love” from the Anglo-Norman Leges Henrici Primi . Yet, rarely has this aphorism’s background been e...

Efficacy of topical vancomycin in preventing surgical site infection following fracture surgery

Aims Fracture-related infection (FRI) is a major cause of morbidity following limb fracture surgery. Topical vancomycin has gained popularity as an adjunct to systemic prophylaxis; however, concerns regarding nephrotoxicity, impaired bone healing, and wound complications remain....

Mitochondrial carrier SLC25A34 links clock, diet, and temperature control of adipocyte lipid cycling

Adipocyte lipid metabolism is coordinated by circadian rhythms, diet, and environmental temperature, but how these diverse signals are molecularly integrated remains unknown. We showed that these cues converge on the orphan mitochondrial transporter SLC25A34 to orchestrate lipid...

The DESI Y1 RR Lyrae Catalog. I. Empirical Modeling of the Cyclic Variation of Spectroscopic Properties and a Chemodynamical Analysis of the Outer Halo

Abstract We present the catalog of RR Lyrae stars (RRLs) observed in the first year of operations of the Dark Energy Spectroscopic Instrument (DESI) survey. This catalog contains 6240 RRLs out to ∼120 kpc from the Galactic center and over 12,000 individual epochs with homogeneous...

Tighter bounds on the expected absorbing time of Ungarian Markov chains

Abstract In 2023 2023 $2023$ , Defant and Li defined the Ungarian Markov chain bold upper U Subscript upper L U L $\mathbf{U}_L$ associated to a finite lattice upper L L $L$ . This Markov chain has state space upper L L $L$ , and from any state x element of upper L x ∈ L $x \in L...

The DESI Y1 RR Lyrae Catalog. II. The Metallicity Dependency of Pulsational Properties, the Shape of the RR Lyrae Instability Strip, and Metal Rich RR Lyrae

Abstract RR Lyrae stars (RRLs) are valuable probes of both Milky Way assembly and stellar-evolution physics. Using a sample 6240 RRLs obtained in the first year of the Dark Energy Spectroscopic Instrument (DESI) survey, we investigate the metallicity of RRLs and its correlation w...

Stereotactic Radiosurgery for Thalamic Brain Metastases: A Retrospective Analysis and Literature Review.

BACKGROUND AND OBJECTIVES: The thalamus, a neural processor and integrator for forebrain activities, is an uncommon site for metastatic lesions. Stereotactic radiosurgery (SRS) has become a noninvasive treatment for brain metastases. This study assesses the efficacy, safety, and...