University College London

Porting GLASS to the Python Array API: A Clear View to GPU Portability

GLASS is a Python library designed to generate full-universe cosmological simulations for large-scale galaxy surveys. Historically, the use of NumPy has been essential to GLASS’ success, allowing rapid development and integration with a wide range of existing cosmological softwar...

Pricing and hedging renewable power purchase agreement floors under stochastic generation

Abstract Renewable power purchase agreements (PPAs) expose generators and offtakers to capture‐price risk because realised revenue depends on prices during renewable production hours. Downside protection written on the production‐weighted settlement price is economically relevant...

Self-Powered Organic Photodetectors with Record Bandwidth for Simultaneous Energy Harvesting and High-Speed Optical Wireless Communication

Organic photodetectors (OPDs) are attracting increasing interest as receivers for visible light communication (VLC) systems due to their high sensitivity, low-cost fabrication, and mechanical flexibility. Recent efforts have focused on self-powered OPDs that can simultaneously en...

The diagnosis and management of primary mediastinal B‐cell lymphoma: A British Society for Haematology guideline

Summary Primary mediastinal B‐cell lymphoma (PMBCL) is a distinct clinicopathological entity within the spectrum of aggressive B‐cell lymphomas, characterised by unique clinical, immunophenotypic and molecular features. Since publication of the 2019 British Society for Haematolog...

Efficacy and safety of fenfluramine in Dravet syndrome: The impact of patient clinical characteristics

Abstract Objective To assess the efficacy and safety of fenfluramine in patients with Dravet syndrome (DS) stratified by age, number of previously attempted antiseizure medications (ASMs), and SCN1A pathogenic variant status. Methods In this post hoc analysis, data from three ran...

The Relationship Between Social Media Use and Self-Esteem in Attention-Deficit Hyperactivity Disorder and Autism: A Scoping Review

Background: There is growing interest in the role of social media (SM) in the mental health (MH) and well-being of neurodivergent people, with evidence of both potential harms and benefits to engagement. Here, we undertook a scoping review to explore existing research into links...

Correlation of polygenic risk score and clinical phenotype in patients with genetic generalized epilepsy

Abstract Objective The polygenic risk score (PRS) for individuals with genetic generalized epilepsy (GGE) quantifies the common risk variants in genes identified in genome‐wide association studies. We hypothesized that the phenotype of GGE patients differs based on their GGE PRS....

Strategic roadmap for delivery of clinical trials in rare childhood central nervous system (CNS) tumours: a multi-stakeholder consensus

Abstract Rare paediatric central nervous system (CNS) tumours comprise a biologically-heterogeneous group of low-incidence diseases that present significant challenges to both therapeutic development and clinical research, limiting the availability of high-quality evidence to gui...

The global cardiovascular-kidney-liver-metabolic burden from 1990 to 2023

Background The cardiovascular-kidney-liver-metabolic (CKLM) framework represents the multi-organ interplay of systemic metabolic disorders that drive the global burden of cardiovascular diseases (CVD). Methods This study is a descriptive epidemiological analysis of the Global Bur...

Exploring teacher retention in Denmark as an entangled phenomenon: unpacking variations within and across municipalities

Drawing on agential realism and critical cultural geography, this article sets out to explore teacher retention in Denmark as an entangled phenomenon with particular focus on unpacking variations in retention rates within and across municipalities and on gaining insights into tem...

Reducing Emotional Burden Carried by Neurodivergent Students in School: Perspectives From Students and School Staff

Abstract Purpose Compared to neurotypical peers, neurodivergent students experience increased exposure and more intense responses to commonly upsetting events (emotional burden), contributing to poor mental health. Student and staff perspectives offer insights into sources of emo...

Intra-abdominal Bowel Dilation in Experimental Gastroschisis Is Associated With a Modifiable Transcriptomic Program of Intestinal Dysfunction

OBJECTIVE: To characterize intestinal transcriptional profiles in gastroschisis, their temporal evolution, and response to fetal intervention. SUMMARY BACKGROUND DATA: Gastroschisis causes significant intestinal dysfunction, with intra-abdominal bowel dilation clinically shown to...

The Association of Umbilical Cord Blood Neurofilament Light With Nonreassuring Fetal Status: A Prospective Observational Study

( Int J Gynaecol Obstet . 2026 Mar;172(3):1491–1500. doi:10.1002/ijgo.70421) A prospective observational study explored whether neurofilament light (NfL), a marker of neuronal injury, can be reliably measured in umbilical cord blood and whether it is associated with nonreassuring...

Neurobiological correlates of longitudinal grey matter volume changes in preclinical Alzheimer’s disease

Background: Structural brain changes during the earliest asymptomatic stages of Alzheimer's disease (AD) remain poorly understood. Previous research in preclinical AD shows heterogeneous findings, reporting both subtle neuronal loss and paradoxical increases in grey matter (GM) v...

Ion Adsorption at Polymer Membranes: Surface Polarity Controls Interfacial Structuring in LiCl Solutions

Abstract Membrane distillation–crystallization (MD–MCr) has emerged as a promising route for recovering valuable salts and water from brine and wastewater streams; however, its industrial implementation depends critically on membrane robustness, scalability, and material chemistr...

Bounded diameter monochromatic component covers

Abstract Ryser conjectured that every ‐edge‐coloured complete graph can be covered by monochromatic trees. Motivated by a question of Austin in analysis, Milićević predicted something stronger — that every ‐edge‐coloured complete graph can be covered by monochromatic trees of bou...

Opting in instead of opting out: an open-ended, arts-based workshop method for exploring refugees' experiences of disasters

Purpose Arts-based research has received growing interest and is suggested to be appropriate for sensitive topics or working with vulnerable people. This article explores the use of a multi-arts-based workshop, as an open enquiry approach, to explore refugees' experiences of disa...

Why Is the Mental Health of the Youngest American Workers in Decline?

The worsening mental health of young workers drives what appeared to be the disappearance of the age-related U-shape in wellbeing and the hump-shape in illbeing over the last decade. Using repeat cross-sectional data, we show that, whilst illbeing remains hump-shaped among non-wo...

Trade-Offs Between Ranking Objectives: Descriptive Evidence and Structural Estimation

When designing product rankings, online retailers and platforms choose which outcome to maximize: revenues from commissions or markups, the number of transactions, or consumer welfare. These objectives need not align, creating potential trade-offs. This paper studies how rankings...

Paediatric therapeutic development workshop on osteosarcoma

The fourth Paediatric Therapeutic Development Workshop focused on osteosarcoma, the most common primary bone cancer in children and young adults. Current treatment of osteosarcoma comprises surgery and chemotherapy. Outcome has shown very little improvement over the last four dec...