The University of Tokyo

Computed Tomography Reconstruction Algorithm Using Markov Random Field Model

X-ray computed tomography (CT) reveals the materials’ internal structures non-destructively from a tilt series of projected images. Filtered back projection (FBP) is a widely-adopted reconstruction algorithm in CT owing to its small computational cost. Under low-dose or sparse-vi...

GH172 Difructose Dianhydride I Synthase: A Two‐Stepped Journey via Glycosylation and Cyclization Using QM/MM Metadynamics

ABSTRACT The difructose dianhydride I synthase/hydrolase catalyzes the reversible transformation of inulobiose into difructose dianhydride I, a component of caramel. The proposed reaction mechanism of such a transformation consists of a glycosylation step followed by a cyclizatio...

Baseline Eating Behaviors and Responsiveness to TelePhysio in Older Patients with Type 2 Diabetes: An Exploratory Secondary Analysis of the TelePhysioT2D Trial

Background/Objectives: Telerehabilitation for physiotherapy programs (TelePhysio) has been shown to improve knee extension force (KEF) in older patients with type 2 diabetes mellitus (T2DM), but factors associated with responsiveness remain unclear. This exploratory secondary ana...

Grass Expression Atlas: an RNA-seq-based expression resource for grass species

Abstract Grass Expression Atlas (GExA) is an interactive web-based resource for rapid exploration of gene expression across diverse tissues, developmental stages, and conditions in grass species. GExA integrates publicly available RNA sequencing (RNA-seq) datasets for four millet...

Long Intramural Left Coronary Artery Confined to the Left Sinus of Valsalva with Diastolic Deformation: A Case Report

Abstract Background Anomalous aortic origin of a coronary artery (AAOCA) is a rare congenital anomaly. The most frequently reported and surgically treated form involves origin of a coronary artery from the opposite sinus that follows an interarterial course, often termed “maligna...

Advances and challenges in developing expandable human hepatocytes for regenerative medicine.

Liver transplantation remains the only effective treatment for severe liver disease, but donor shortages pose a serious challenge, underscoring the need for alternative therapeutic strategies. Hepatocyte transplantation has been proposed as a promising alternative; however, the l...

Evidence for Optical Cooling of Biexcitons via Polariton-assisted Dissociation Scattering in CuCl

In 1991, a study based on experimental data obtained from a block single crystal of CuCl cooled to 2 K and excited by a strong monochromatic laser beam near the exciton resonance revealed a new emission band. The band was attributed to a scattering process in which a biexciton in...

ProvMind: provenance-grounded reasoning for materials synthesis

Materials process optimization requires reasoning over routes, conditions, tools and material-flow dependencies, yet most computational formulations flatten synthesis procedures into text or ordered steps. We introduce MatProcBench, a provenance-grounded benchmark constructed fro...

Spin-coherence characterization of boron vacancy defects in hexagonal boron nitride with broadband microwave pulses

Negatively charged boron vacancy (VB−) defects in hexagonal boron nitride (hBN) are promising for nanoscale-proximity quantum sensing. To evaluate their performance, it is important to characterize the spin-coherence times T2* and T2. In this study, we realized subgigahertz Rabi...

Cryogenic time-division-multiplexed voltage control for scalable trapped-ion quantum processors

Trapped-ion quantum computers based on the quantum charge-coupled device architecture require on the order of ten trap electrodes per qubit, making the number of vacuum feedthroughs a bottleneck at the system scale. Time-division multiplexed (TDM)-based voltage control for trap e...

An Analysis of Mobility Styles and Carsharing Adoption Intentions in Major Urban Areas of Japan: Evidence from Tokyo, Osaka, and Kanagawa

This study links mobility styles with carsharing intentions and next-generation vehicle preferences in urban Japan. An online survey of licensed drivers in Tokyo Metropolis, Kanagawa Prefecture, and Osaka Prefecture captured mode use frequencies and stated preferences by travel p...

Feasibility to detect rapid change and disappearance of seagrass: Lessons from nearly 80 years of vegetation change in the Ako, Seto Inland Sea, Japan

Abstract. Seagrass meadows provide essential ecosystem services but are declining globally, creating an urgent need for continuous monitoring and management. However, the high cost of commercial satellite imagery and field surveys limits sustained observation, highlighting the ne...

Preferential Nucleation Sites Regulate Hydrogen Bubble Evolution on Mesh Electrodes

Gas-bubble evolution substantially affects the efficiency of gas-evolving electrochemical processes, including water electrolysis. Bubble nucleation, growth, coalescence, and detachment influence the electrode potential, while persistent bubble coverage can impede ionic...

Street-level cooling effects of street trees in Toshima Ward, Tokyo: a field-based microclimate assessment

Street trees can contribute to urban heat adaptation, but their cooling performance depends on street form, surface conditions, and canopy structure. This study examined street-level cooling and humidifying effects at seven street-tree sites in Toshima Ward, Tokyo, using summer f...

H I Absorbers as Beacons of Hidden Structure at z ~ 3: Multi-Component, Metal-Rich Absorption System near a Protocluster

Abstract H i gas traces the large-scale structure and provides the primary fuel for star formation. High-z protoclusters are ideal laboratories to study how H i gas is accreted and consumed during the formation of the most massive structures in the Universe. However, much remains...

Are dispersed rice planting dates linked to higher provincial yields? Evidence from Northeast Thailand

Abstract Planting date is an important determinant of wet-season rice performance in monsoon Asia. However, it is influenced not only by rainfall but also by irrigation access, drainage conditions, and field operability. This study quantified how the spatial distribution and disp...

Implementation and evaluation of geography education using QGIS for Japanese high school students

Abstract. In recent years, demand for geography education using GIS has been growing among junior and senior high school teachers. QGIS has attracted attention because it is freely available and enables advanced spatial visualization and analysis. However, the implementation of Q...

MUSUBOU-AR: An Open-Source Geospatial AR Framework for Integrating Public GIS Data, Field Authoring, and Disaster Walking Tours

Abstract. Conventional hazard maps, public GIS layers, and disaster education materials are essential resources for community disaster risk reduction, but they do not always support in-situ spatial understanding during field-based training. This paper presents MUSUBOUAR, a public...

ESD in higher education in the Philippines: policies shaped through international discourse and national realities

Abstract This study explores the narrative evolution of Education for Sustainable Development (ESD) higher education policy in the Philippines up to its present conceptions. This is done through qualitative methods, namely a policy analysis through the Multiple Streams Framework...

Short‐Term 6PPD‐Q Exposure alters Tight‐Junction‐Related Gene Expression Without Acute Lethality in Japanese Medaka Oryzias latipes

6PPD-quinone (6PPD-Q), a transformation product of the tire antioxidant 6PPD, causes acute mortality in several salmonid species, but its toxicity varies markedly among fish species. Disruption of vascular-barrier integrity and inflammatory signaling has been proposed as a key me...