The Ohio State University

Amphiphilic Lipid–PolymerTriblock Architecturesas Nanocarriers for Therapeutic Delivery

Abstract This study investigates the formation and characterization of nanocarriers derived from the self-assembly of amphiphilic lipid-polymer hybrids (LPHs) engineered with a symmetric ABA block copolymer architecture. In this design, the terminal A-blocks comprise branched hyd...

A Systematic Reflection on the Challenges in Acupuncture and Chinese Medicine Education and Careers in the United States

The relationship between education in acupuncture and Chinese medicine (ACM) and its professional practice can be conceptualized as an integrated “factory–product–market” industrial chain. Within the education sector, ACM schools face a significant predicament. Their core mission...

The majority of 5hmC is nucleosome-associated in naïve B cells

DNA demethylation is essential for gene activation and is primarily mediated by the Ten-Eleven-Translocation (TET) dioxygenase family. TET initiates demethylation by oxidizing 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), a chemically stable derivative that is not onl...

ElectrocatalyticHydrogenation with NanoparticlesDerived from a Cobalt Metal–Organic Framework

Abstract Electrocatalytic hydrogenation (e -H) provides a sustainable route for converting unsaturated organic substrates under mild conditions using renewable electricity as the driving force. Here, we report an MOF-derived cobalt catalyst for the e -H of acetone and pyridine. A...

Valhalla: A phantasm

Abstract This Terms of art examines Valhalla as a phantasmic construct that gathers fantasies of whiteness, masculinity, and militarism across political, religious, and temporal divides. Beginning with invocations of Valhalla by Director of the US Federal Bureau of Investigation...

Identifying the proton donor in electrocatalytic hydrogen evolution by a model hydrogenase

Abstract Proton transfer is essential in all multi-electron transformations. Identifying the proton donor in such processes is crucial to understanding the catalytic mechanism and optimizing activity through pK a matching, which can enhance proton transfer rates. However, aqueous...

Conventional Reporting Standards Conceal High‐Frequency Hearing Deficits After Favorable Ossiculoplasty

OBJECTIVE: To evaluate high-frequency hearing outcomes in ossiculoplasty cases having favorable pure-tone average outcomes within the reporting range set by current guidelines. STUDY DESIGN: Retrospective cohort study. SETTING: Multi-center tertiary care ossiculoplasty outcome re...

Efficacy of Antibiotic-Loaded Stimulan Beads Against Biofilms on Clinically Relevant Orthopedic Implant Surfaces

Background: Bacterial biofilms play a key role in causing periprosthetic joint infection (PJI). Current PJI management strategies commonly combine systemic antibiotic therapy with localized delivery such as antibiotic-loaded cement or beads to achieve effective tissue penetration...

Correlates and Patterns of Adolescents' First Romantic Relationships in Three Low‐ and Middle‐Income Countries

ABSTRACT Objective This study characterizes adolescent romantic relationships in three low‐ and middle‐income countries (LMICs) with varied and evolving family systems. Background Adolescent relationships matter for young people's future outcomes and development. These relationsh...

Multidomain mobility and cognition across the adult lifespan: Stride velocity and cadence are associated with executive function in older adulthood.

= .048) explained an additional 3.4% and 2.8% of variance in executive function beyond age and education. No associations were observed among younger adults. Mobility and cognition relationships may differ across adulthood. In older adulthood, cadence emerged as a distinct mobili...

Willingness to accept local CAFO development: actual water quality information and rural residents’ preferences for means of compensation

Concentrated animal feeding operations (CAFOs) provide low-cost products but often face local opposition due to environmental externalities. Based on a two-time panel discrete choice experiment (DCE) of rural residents living near CAFOs in China, this study quantifies how water q...

Flooding temperature affected corn (Zea mays L.) emergence and root growth

Abstract Background and aims Early season weather fluctuations significantly impact corn ( Zea mays L.) seedling establishment and soil nitrogen availability. This study investigated the effect of flooding duration and temperature after planting on corn emergence, seedling biomas...

A systematic review of African-centered school-based interventions.

Cultural-specific interventions often outperform standard protocols because they align with the identities and lived experiences of the youth they serve. For Black students, African-centered approaches have demonstrated improvements in social-emotional functioning, mental health,...

Exploring community-level gut health amidst COVID-19 pandemic: a proposed application of longitudinal wastewater surveillance

Wastewater-based epidemiology (WBE) offers a unique, scalable method to monitor disease burden at a community level by capturing all individuals within a sewershed. While emerging evidence suggests that SARS-CoV-2 may influence the human gut microbiota, which is essential for hea...

Acute Interstitial Nephritis after Single Dose of Ketorolac.

Acute interstitial nephritis (AIN) is an immunologically mediated cause of acute kidney injury (AKI), most often drug-induced, with NSAIDs being a leading culprit. We present a 39-year-old woman who developed biopsy- proven AIN following a single intramuscular dose of ketorolac,...