The Ohio State University

Comparing Symmetry-Adapted Perturbation Theory to Intermolecular Energy Decomposition Analysis Based on Absolutely Localized Molecular Orbitals

Abstract Energy decomposition analysis (EDA) can provide insight into noncovalent interactions, even though the individual energy components (electrostatics, Pauli repulsion, polarization, dispersion, etc.) are not uniquely defined within quantum mechanics. The present work exami...

Managing growth and puberty concerns in individuals with Duchenne muscular dystrophy: Updated guidance and future directions

Long-term glucocorticoid therapy is standard of care for individuals with Duchenne muscular dystrophy (DMD) but often results in impaired growth and delayed or incomplete puberty, impacting their physical and psychosocial health. Although DMD endocrine care has evolved, leading t...

Sparse Max-Affine Regression

Abstract. This paper presents sparse gradient descent as a solution for variable selection in convex piecewise linear regression where the model is given as the maximum of [Formula: see text]-affine functions [Formula: see text] for [Formula: see text]. Here, [Formula: see text]...

Facilitating best practices in practicum training in clinical neuropsychology: introducing the North American Association of practicum sites in neuropsychology (NAPSN) organizational training guidelines

INTRODUCTION: The North American Association of Practicum Sites in Neuropsychology (NAPSN) was established in 2023 to support external practicum programs in urban, suburban, and rural areas in the United States and Canada by providing resources for member practicum programs and s...

Better together: Multi‐Agent system teamwork

Abstract While most present‐day multi‐agent system (MAS) deployments involve teams of agents within a single institution orchestrated by one or a few actors, some researchers are already beginning to appreciate the promise of more complex ecosystems consisting of hybrid human‐age...

Myocardial work in light-chain and transthyretin-related amyloidosis with preserved ejection fraction: a cardiovascular magnetic resonance study

Abstract Objectives To investigate pressure–volume loop (PV-loop) changes by cardiovascular magnetic resonance (CMR) imaging in cardiac amyloidosis (CA) patients with preserved left ventricular ejection fraction (LVEF), and to assess PV-loop parameters’ potential as subtype diffe...

Nonlinear Quantum Effects Drive Grotthuss Proton Conduction in Structured Electrolytes Based on Deep Eutectic Solvents

ABSTRACT Structured electrolytes based on deep eutectic solvents (DESs) face electrochemical limitations of vehicular diffusion due to high viscosities often leading to low conductivities. Here, we demonstrate that the inverse relationship between viscosity and conductivity in DE...

What Happens After They Do: How Black Men Experience and Make Meaning of Therapy

Black men continue to experience significant mental health disparities while remaining among the least likely to utilize psychotherapy. Existing scholarship has provided important insights into barriers to treatment and help-seeking among Black men. However, less attention has be...

Specialized Nutrition Products in Pediatric Medical Care: Clinical Applications, Formulation, Regulation, and Future Directions

Specialized nutrition products are often used as a component of nutrition care across a spectrum of acute and chronic pediatric medical conditions. These products differ from conventional foods due to their clinical purpose, composition, and context of use, yet these distinguishi...

Urinary neutrophil gelatinase-associated lipocalin concentration: a baseline study for establishing reference ranges in preterm neonates

Abstract Background Acute kidney injury (AKI) affects up to 48% of extremely preterm neonates and is associated with significant morbidity and mortality. However, AKI diagnosis remains challenging in this population due to limitations of traditional markers like serum creatinine...

Structural basis for regulating lipopolysaccharide transmembrane transport

Gram-negative bacteria are surrounded by a multilayered cell envelope with a mostly impermeable outer membrane that provides intrinsic resistance to many antibiotics1–5. The outer membrane is an asymmetrical bilayer with phospholipids in the inner leaflet and lipopolysaccharide (...

The chromatin-organizer Satb1 modulates regulatory T cell activity within the tumor microenvironment

Regulatory T cells (Tregs) are essential for maintaining immune homeostasis and preventing autoimmune diseases, but are also a major cellular constituent of the tumor microenvironment (TME) that facilitates cancer progression. Identifying differences in Treg subtypes to specifica...

The Next Frontier in Open Access: Transforming Library Workflows

The evolution of Open Access (OA) business models has outpaced the development of efficient and effective workflows within academic libraries. OA publishing agreements have introduced operational complexities that extend beyond financial commitments. Libraries are increasingly ab...

Prenatal stress reprograms placental signaling and opposes maternal immune activation effects in the fetal brain

Abstract Prenatal psychosocial stress and maternal immune activation (MIA) increase risk for overlapping offspring psychiatric disorders, but whether they influence fetal neurodevelopment through shared or distinct mechanisms is unclear. Positioned at the interface of maternal an...

High-Precision Differential Radial Velocities of C3PO Wide Binaries: A Test of Modified Newtonian Dynamics (MOND)

Wide-binary stars, separated by thousands of AU, reside in low-acceleration regimes where Modified Newtonian Dynamics (MOND) predicts deviation from Newtonian gravity. However, Gaia radial velocities (RVs) lack the precision to resolve the small velocity differences expected in t...

Investigation of One-Step Shear Stress and Moderate Electric Field Combination for Controlling Microcystis Aeruginosa, a Bloom-Forming Cyanobacterium

Harmful algal blooms (HABs) pose significant threats to the contamination of drinking water and the quality of food production. In this study, the effectiveness of the simultaneous treatment of shear stress and moderate electric field (SS+MEF) for controlling the growth of cyanob...

Disclosing pollution: causal impacts of key emission unit listings on Shanghai's housing market

Abstract We provide causal estimates of the effect of Shanghai's key emission unit listings on nearby housing prices. Implemented in 2016, the disclosure policy requires annual public disclosure of designated polluting firms and their pollution information. Using repeated cross-s...

The clock gene cycle synchronizes circadian metabolic oscillations uniquely in reproductively active Culex pipiens females

Abstract The circadian clock regulates changes in daily metabolite abundance, coordinating animal activity, feeding and rest. The Northern house mosquito, Culex pipiens , also displays seasonal changes between periods of reproductive activity and overwintering diapause, regulated...

Anticoagulation Treatment Response Among Phenotypic ESUS Clusters: Evidence From CASPR

ABSTRACT Objective To evaluate treatment effect heterogeneity across phenotypic clusters of patients with cryptogenic embolic stroke using causal inference methods. Methods From a retrospective, multicenter cohort of patients with cryptogenic embolic stroke, we estimated the trea...

CORAL: a machine learning algorithm to identify coronary microvascular disease from doppler coronary blood flow patterns

The direct diagnosis of coronary microvascular disease (CMD) in patients has remained elusive, relying on combinatorial criteria for diagnosis. Recent data in mice suggested that coronary blood flow (CBF) patterns harbor “fingerprints” that may be novel non-invasive indicators of...