Sun Yat-sen University

Anion‐Doped Manganese Oxides Enabling Relay Catalysis for Aerobic Alcohol Ammoxidation

ABSTRACT The development of noble‐metal‐free heterogeneous catalysts for room‐temperature aerobic ammoxidation of alcohols to nitriles represents an enduring challenge, primarily hampered by unselective lattice‐oxygen over‐oxidation via the classical Mars–van Krevelen (MvK) pathw...

Dual Compartmentalization of GSTA4 Suppresses Ferroptosis to Drive Antiandrogen Resistance in Prostate Cancer

ABSTRACT Resistance to second‐generation antiandrogens poses a major therapeutic challenge in castration‐resistant prostate cancer (CRPC). While ferroptosis evasion has been implicated in treatment failure, the key molecular determinants driving this evasive process are poorly un...

When Does Error Correction Help? A Payload-Matched Study of Post-Hoc and End-to-End ECC in Neural Image Watermarking

Error-correcting codes are routinely bolted onto neural image watermarkingdecoders, and increasingly integrated into training. Neither practice comes with arule for when it helps, and comparisons rarely control for the payload the codeitself consumes. Using MBRS as a fixed backbo...

Galactosylated Camptothecin (Gal-CPT) as a New Anticancer Prodrug Sequentially Activated by Dual Tumor-Specific Enzymes

Abstract Camptothecin (CPT) and its clinically used derivatives are still plagued by severe off-target toxicities. In this study, we designed a galactosylated CPT (Gal-CPT) prodrug incorporating an enzymatically cleavable diethylene glycol linker. In vivo experimental results ver...

A positive feedback loop between HNRNPF and GRHL2 drives NEK8-mediated prostate cancer progression

Prostate cancer (PCa) remains a major cause of cancer-related mortality in men, especially in advanced stages. The role of Heterogeneous Nuclear Ribonucleoprotein F (HNRNPF) in PCa progression is poorly defined. The function and mechanism of HNRNPF were investigated using in vitr...

A New Genus and Two New Species of Freshwater Crab (Crustacea: Brachyura: Potamidae) with Unusual Coiled Tip of Male Second Gonopods from Yunnan, Southwestern China

n. gen. from known potamid genera. Notes on the general biology of the two new species are also included.

Dietary Supplementation of Auraptene, a Major Component in Citrus reticulata Blanco, Prevents Acute Liver Injury Associated with Apoptosis and Inflammation

Abstract Auraptene (AP), a coumarin derivative abundant in citrus peels, exhibits diverse bioactivities; however, its role in acute liver injury and the underlying mechanisms remain elusive. This study investigates the hepatoprotective effects of AP against carbon tetrachloride (...

When Does Error Correction Help? A Payload-Matched Study of Post-Hoc and End-to-End ECC in Neural Image Watermarking

Error-correcting codes are routinely bolted onto neural image watermarkingdecoders, and increasingly integrated into training. Neither practice comes with arule for when it helps, and comparisons rarely control for the payload the codeitself consumes. Using MBRS as a fixed backbo...

Three-dimensional in situ stress reconstruction in deep hard rock by integrated DCDA–DSA inversion of oriented cores

Core-based observables constrain different components of the three-dimensional (3D) in situ stress state in deep hard-rock engineering and therefore require consistent integration. A closed-form DCDA–DSA inversion was developed in which diametrical core deformation analysis (DCDA...

Mechanochemical Encapsulation of Enzymes in a Highly Hydrophilic HOF: Harnessing Pore Microenvironment for Enhanced Biocatalysis

ABSTRACT Enzymes immobilized within hydrogen‐bonded organic frameworks (HOFs) often suffer from reduced catalytic activity due to mass transfer limitations and pore channel blocking by residual organic solvents from conventional solution‐phase synthesis. In addition, the correlat...

Telluria xinjiangensis sp. nov., a Gram-negative bacterium isolated from ripe melon fruit and its genetic characteristics

Abstract Background The genus Telluria (family Oxalobacteraceae, phylum Pseudomonadota ) comprises phylogenetically and ecologically diverse bacteria recovered from environmental, clinical, and plant-associated habitats. However, representatives associated with fresh fruit remain...

Public Charging Infrastructure Deployment and Credit Risk of Rural Commercial Banks in China: Evidence from Sustainable Mobility Infrastructure

This study examines the relationship between public electric-vehicle charging-infrastructure deployment and the credit risk of rural commercial banks in China. Using an unbalanced panel dataset of 180 RCBs across 10 provinces from 2016 to 2022, this paper employs a two-way fixed-...

Phenothiazine-Driven Autophagic Response in Macrophages as an Anti-cutaneous Tuberculosis Approach

Abstract Cutaneous tuberculosis (CTB), caused by Mycobacterium tuberculosis (Mtb) infection of the skin, remains a global health burden, underscoring the urgent need for more effective drugs and therapeutic strategies. In this study, we discovered a phenothiazine-based derivative...

Leveraging E-Commerce Platform Rewards to Promote Green Consumption: How Reward Types Influence Consumers’ Sustainable Choices

Promoting sustainable consumption is essential for advancing the United Nations Sustainable Development Goals (SDGs). However, encouraging consumers to translate sustainable intentions into green consumption remains challenging. Although e-commerce platforms increasingly implemen...

Clinical and molecular epidemiology of type 2 diabetes mellitus-associated intestinal Staphylococcus aureus colonization

ABSTRACT Intestinal Staphylococcus aureus colonization in type 2 diabetes mellitus (T2DM) remains poorly defined with respect to prevalence, clinical associations, and molecular characteristics. We investigated intestinal S. aureus colonization in 142 patients with T2DM and chara...

Association of hospital bed and primary care supply with avoidable hospitalizations in China: a longitudinal panel study, 2016–2023

The continuous expansion of hospital capacity presents a fundamental dilemma. While adequate inpatient resources are essential for meeting population health needs, excess bed availability may be associated with potentially avoidable healthcare utilization. This study aimed to eva...

Supramolecular Salicylic Acid Chemical Peeling Combined with Supramolecular Active Zinc for Malassezia Folliculitis: Efficacy and Safety from a Multicenter, Single-Arm Trial

Traditional antifungal therapy for Malassezia folliculitis (MF) is often associated with high recurrence rates and limited long-term options. This study evaluated the efficacy and safety of 30% supramolecular salicylic acid (SSA) combined with supramolecular active zinc (SAZ) in...

Institutional tensions in HIV treatment: challenges in providing free antiretroviral drugs under China’s ‘Four Frees and One Care’ policy

Abstract China’s ‘Four Frees and One Care’ policy provides people living with HIV (PLHIV) with free antiretroviral drugs (ARVs), while the recent inclusion of new ARVs in medical insurance policy has created policy overlap. Guided by the Institutional Analysis and Development (IA...

Perioperative prediction of ideal postoperative recovery after kidney transplantation: a multicenter retrospective cohort study

Kidney transplantation is the preferred treatment for end-stage renal disease, but early postoperative outcomes remain heterogeneous. Textbook outcome (TO), a composite measure of an ideal postoperative recovery trajectory, has emerged as a meaningful indicator of surgical qualit...

Perirenal fat thickness was associated with reduced estimated glomerular filtration rate in the hospital-based population: a mediation analysis

It is unclear how perirenal fat thickness (PrFT) and impaired renal function are related, particularly in patients with metabolic risk factors. A hospital-based cohort of individuals was examined to determine whether perirenal fat thickness, as measured by magnetic resonance imag...