Institution
Sichuan University
Recent research
- Materials & EnergyOpen access
Abstract Electrochemical oxidation is typically regarded as incompatible with hydrogen intermediate formation, particularly at highly positive potentials where surface hydrogen species are expected to be rapidly oxidized. Formaldehyde oxidation reaction (FOR) on palladium represe...
- Physics & SpaceOpen access
Self-organized optofluidic locking enables stable single-frequency lasing in dynamic liquid media
Liquid-state lasers are promising wavelength-agile, reconfigurable coherent light sources, but fluid gain media introduce Brownian motion, thermal transport, and refractive-index fluctuations that destabilize single-frequency emission. Here, we demonstrate that nonequilibrium flu...
- Engineering & TechnologyOpen access
All-solid-state lithium batteries based on oxide solid electrolytes have attracted extensive attention due to their high safety, wide electrochemical stability window, excellent thermal stability and superior mechanical strength. However, their practical application is still limi...
- BiologyOpen access
Antioxidant Strategies for Inherited Retinal Degenerations in the Era of Gene Therapy
Inherited retinal degenerations (IRDs) are a genetically heterogeneous group of disorders characterized by progressive loss of photoreceptors and retinal pigment epithelium, leading to irreversible vision impairment. Although gene therapy has transformed the therapeutic outlook f...
- BiologyOpen access
Abstract Introduction Vestibular-related symptoms are increasingly recognized as being significantly associated with depressive symptoms, yet the strength and consistency of this association remain unclear due to conflicting evidence across studies. It is also uncertain whether t...
- AI & ComputingOpen access
Heterogeneity in cancer: molecular mechanisms and therapeutic strategies
Cancer heterogeneity drives therapeutic failure, resistance, and relapse and encompasses variation across genetic, cellular, tissue, organ, and systemic scales. Existing frameworks define malignant capabilities and tumor–microenvironment interactions but less explicitly address h...
- Health & MedicineOpen access
Poor oral health is common among community-dwelling older adults and has been associated with frailty. However, evidence regarding the association between specific oral health indicators and frailty remains unclear. This systematic review aimed to summarize the current evidence o...
- Materials & Energy
Structure-Guided Upcycling of Polyamide 6 Waste into Ultra-Strong Adhesives
Abstract Upcycling polymer waste, especially polyamide 6 (PA6), remains challenging because it is difficult to simultaneously exploit its intrinsic structural advantages and meet the performance requirements of high-value applications. Herein, we propose a structure-guided upcycl...
- AI & ComputingOpen access
CCA-ID: Confidence-calibrated adaptive intrusion detection with selective routing for IoT networks
The rapid expansion of Internet of Things (IoT) deployments has extended the cyber-attack surface. In resource-constrained IoT monitoring environments, maintaining always-on deep or ensemble-based intrusion detection can be challenging for high-rate, real-time traffic. This study...
- Health & MedicineOpen access
Family members frequently participate in end-of-life (EOL) decision-making for terminally ill older adults; however, family-member preferences for the patient may not align with the patient’s own preferences. Such discordance can complicate treatment planning and efforts to provi...
- Health & MedicineOpen access
Major depressive disorder (MDD) is more prevalent in women and has been linked to female reproductive timing. However, the genetic mechanisms underlying these associations remain unclear. Reproductive milestones are temporally structured and biologically interrelated, suggesting...
- Health & Medicine
Insights into Shared Genetic Architecture Linking Thyroid Function and Cancer
Abstract Background Growing evidence suggests a complex interplay between thyroid function and various cancers, and yet their shared genetic basis and underlying mechanisms remain unclear. Methods This study leveraged large-scale genome-wide association study (GWAS) summary for f...
- Climate & Environment
ABSTRACT Based on typology of cultural attributes, the present study classifies the middle to late Western Han period 21 bronze objects from western Hunan into two categories: objects with indigenous characteristics, and with Central Plains characteristics. The analytical results...
- Health & MedicineOpen access
Senescence-associated secretory phenotype (SASP)-related inflammatory programs have been implicated in type 2 diabetes mellitus (T2DM), yet blood-based candidates have not been systematically screened and validated across independent cohorts. We adopted standardized senescence si...
- Society & EconomicsOpen access
ABSTRACT Background Sleep disturbances are common after hip fracture surgery and may adversely affect postoperative recovery. However, the longitudinal course of sleep quality and its relationship with functional recovery remain poorly understood. This study aimed to characterize...
- Materials & Energy
Abstract Fe3O4, the first reported nanozyme and the first FDA-approved transition-metal-based nanomaterial, holds promise for antibacterial therapy but is limited by poor ROS catalytic activity and utilization. Inspired by macrophage-like bacterial capture and insect wing micro/n...
- Health & MedicineOpen access
ZIF-8-Based Smart-Responsive Nanocomposites for Cutaneous Wound Healing: A Review
Abstract Cutaneous wound healing is a complex process that requires precise management. In recent years, intelligent, responsive biomaterials have played a crucial role in guiding wound healing through these stages in a physiologically ordered manner. Zeolitic imidazolate framewo...
- Health & MedicineOpen access
Although timolol ophthalmic solutions or hospital-compounded formulations have been used off-label for the treatment of superficial infantile hemangioma (IH), no topical timolol formulation has been developed specifically for this indication. This study was the first to develop a...
- Health & MedicineOpen access
PD-1/PD-L1 blockade can produce durable tumor control, yet primary, adaptive, and acquired resistance remain common. Existing accounts often catalogue resistance by cellular compartment, obscuring the coordinated nature of tumor adaptation. Here, we introduce immune-pressure redi...
- Health & MedicineOpen access
ABSTRACT Purpose This exploratory study integrates aqueous humour metabolomic data with clinical and imaging features to examine candidate biomarkers and characterize multimodal patterns associated with persistent diabetic macular edema (pDME). Methods In this prospective cohort...