Sichuan University

Enhanced Energy Storage Performance of High‐Temperature Dielectric Films by Internally Constructing Oriented Microfibril Structure

ABSTRACT High‐temperature dielectric films are essential components for capacitive energy storage in severe environments, ranging from hybrid electric vehicles to power systems. However, the surge in leakage current at elevated temperatures leads to a dramatic decrease in dischar...

Frequency security-aware production scheduling of utility-scale off-grid renewable P2H systems coordinating heterogeneous electrolyzers

Renewable power-to-hydrogen (ReP2H) enables large-scale renewable energy utilization and supports the decarbonization of hard-to-abate sectors, such as chemicals and maritime transport, via hydrogen-based renewable ammonia and methanol fuels. As a result, utility-scale ReP2H proj...

Lactylation as a potential epigenetic and metabolic modulator of cuproptosis in health and disease: Current evidence and hypotheses

As a lactate-derived post-translational modification, lactylation plays a vital role in connecting cellular glycolysis with the regulation of cuproptosis, a unique form of cell death triggered by copper overload. The article explores the growing relationship between lactylation a...

Fatigue‐Resistant Mechanically Interlocked Co‐Crosslinked Polyimide Films for Reliable High‐Temperature Capacitive Energy Storage

ABSTRACT During long‐term operation, repeated thermal expansion and contraction inevitably generate cyclic thermal stresses that cause dielectric film buckling, cracking, and eventual device failure. As promising candidates for next‐generation dielectric films, polyimides (PIs) a...

Evolution mechanism of damage locations in drift region of SiC MOSFETs under heavy ion irradiation

This paper investigates the evolution mechanism of severe thermal damage locations in the drift region of the SiC MOSFETs under different applied drain voltages (VDS(irra)) during heavy ion irradiation using 587 MeV 36Kr ions. It is interesting to find from the post-irradiation b...

Differential associations of aging attitude risk with depression, anxiety, and suicide-related risk among older Chinese adults: a network analysis and GGMNIRA-based simulated intervention study

Attitudes toward aging reflect how individuals understand and appraise their own aging process and may be closely associated with mental health in later life. Previous studies have primarily examined associations of attitudes toward aging with depression, anxiety, and suicide-rel...

Advanced detection of carcinogenic heterocyclic amines in meats: an overview of analytical and nanotechnology methods

Abstract Despite extensive research on the formation and health risks of heterocyclic amines (HAs) in cooked meats, there is a gap in comparative analysis of advanced detection methods, particularly juxtaposing classical analytical techniques against emerging nanotechnology‐based...

Unleashing the Potential of Autologous Platelet Concentrates in Bone Regeneration: A Focus on Their Synergy With Biomaterials

ABSTRACT Bone defects present significant clinical challenges worldwide, as conventional treatments such as autografts and allografts are constrained by limited supply, immune risks and insufficient bioactivity. Derived from the patient's own venous blood via centrifugation, auto...

Intratumoral microbiota: spatiotemporal dynamics, microenvironmental immune reprogramming, and immunotherapeutic implications

The discovery of intratumoral microbiota has challenged the traditional view of tumors as sterile environments and revealed a previously unrecognized layer of complexity within the tumor microenvironment (TME). Accumulating evidence indicates that microorganisms residing in tumor...

Acupuncture and Moxibustion for Neck Pain: A Clinical Practice Guideline

ABSTRACT Background Neck pain (NP) is a leading cause of disability worldwide. Pharmacological treatments often provide limited benefits and may be associated with adverse effects, highlighting the need for effective non‐pharmacological options. Aim To develop evidence‐based reco...

Overcoming the Dark Current–Spectral Range Trade‐Off in Room‐Temperature Two‐Dimensional Photodetectors via Photothermal‐Assisted Tunneling

ABSTRACT The intrinsic trade‐off between low dark current and broadband detection fundamentally limits the performance improvement of 2D photodetectors. Here, we report a MoTe 2 /h‐BN/graphene tunneling heterostructure photodetector that synergistically integrates the high insula...

Mass Spectrometry Imaging Reveals Biodistribution and Biotransformation of Black Phosphorus

ABSTRACT Black phosphorus (BP) holds significant potential in biomedicine, biosensing, and phototherapy; however, its instability and the poor understanding of its in vivo fate have limited its applications. Here, we developed an integrated label‐free mass spectrometry imaging (M...

Neutrophil Extracellular Trap‐Mimetic DNA Nets Enable Concurrent Bacteria‐Targeted Eradication and Toxin Neutralization

ABSTRACT Current antibacterial therapies often suffer from limited bacterial selectivity, host‐cell toxicity, and inflammation triggered by toxin release during bacterial killing. Here, we report a neutrophil extracellular traps (NETs)‐mimetic, dopamine‐incorporated DNA net, term...

Lactobacillus gasseri LG-G12 Alleviates High-Fat Diet-induced Obesity through Gut Microbiota-Bile Acid Axis

Abstract The role of probiotics in weight management remains controversial. In this study, we found that Lactobacillus gasseri LG-G12 exhibits gut colonization capacity and metabolic regulation potential in vitro. In vivo, LG-G12 alleviated high-fat diet-induced weight gain and v...

Staged Orthoplastic Soft-Tissue Reconstruction of Complex Tibial Fracture-Related Infection Using a Chimeric Anterolateral Thigh Free Flap After Failed Soleus Muscle Flap: A Case Report

A complex tibial fracture-related infection (FRI) after local-flap failure may require staged source control, dead-space management, and vascularized soft-tissue reconstruction. A 60-year-old man with type 2 diabetes developed FRI after an industrial injury causing a localized in...

Delayed deterioration after surgical treatment of a spinal dural arteriovenous fistula detected by three spinal angiographies: Case report

Spinal dural arteriovenous fistulas (DAVFs) are the most common subtype of spinal arteriovenous malformations, and they often cause progressive myelopathy. Early detection and intervention are critical to preventing irreversible neurological deficits. Selective spinal angiography...

Neutrophil Extracellular Trap‐Mimetic DNA Nets Enable Concurrent Bacteria‐Targeted Eradication and Toxin Neutralization

ABSTRACT Current antibacterial therapies often suffer from limited bacterial selectivity, host‐cell toxicity, and inflammation triggered by toxin release during bacterial killing. Here, we report a neutrophil extracellular traps (NETs)‐mimetic, dopamine‐incorporated DNA net, term...

Retinal Microvascular Abnormalities, White Matter Injury, and Cognitive Impairment in Carotid Stenosis or Occlusion

Background Severe carotid artery stenosis or occlusion (CASO) is associated with white matter injury and cognitive impairment, but markers of accompanying microvascular dysfunction remain incompletely characterized. We investigated the relationships among retinal microvascular ab...

Oncolytic Virus-like Nanoparticle Targets the Golgi Apparatus via Sphingomyelin

Abstract The Golgi apparatus (GA) has emerged as a promising target for cancer therapy. Commonly, therapeutics are guided to the GA by recognizing specific receptors on the GA membrane. However, the low and heterogeneous expression of these receptors often results in suboptimal t...

Taking a clinical history in adolescents and adults presenting with seizures or epilepsy

Abstract Despite advances in EEG, neuroimaging, and other diagnostic technologies, a carefully obtained clinical history remains the cornerstone of diagnosis, classification, and treatment planning. However, structured guidance on history‐taking that integrates state‐of‐the‐art e...