Sichuan University

Head-up lateral positioning during emergence from anaesthesia after ambulatory adenotonsillectomy in children: protocol for a multicentre randomised controlled trial

Tonsillectomy and adenoidectomy are common paediatric surgeries, with > 50% of children experiencing postoperative respiratory adverse events (PRAEs). Existing mitigation strategies have limitations, and evidence on positional interventions (e.g. lateral/semi-reclined) specifical...

Digital echoes of death and dying distress among family members of intensive care unit patients: A qualitative study

Objectives To explore how ICU family members experience and articulate death and dying distress through social media narratives. Methods This study employed a qualitative design informed by the socioecological model and a constructivist epistemological perspective. Data were draw...

Mutual Optimization of Label Prediction and Node Representations for Multi-Label Node Classification

Multi-label node classification requires capturing complex label-co-occurrence patterns, which are critical for accurate predictions. However, traditional methods often treat label prediction as an independent task, overlooking the semantic relationships and dependencies between...

Preoperative platelet-to-lymphocyte ratio and post-hepatectomy hemorrhage risk after elective hepatectomy: a single-center cohort study with exploratory calendar-time assessment of a candidate cutoff

Post-hepatectomy hemorrhage (PHH) is clinically important after liver resection, yet simple preoperative bleeding risk markers remain limited. We assessed whether preoperative platelet-to-lymphocyte ratio (PLR) was associated with PHH and derived an ROC-based threshold. In this a...

Extraventricular neurocytomas stratified by tumor location and histological subtype: clinical features, radiology, pathology, and prognosis

Abstract Objective To compare the differences in clinical manifestations, imaging features, histological characteristics, and prognostic outcomes of extraventricular neurocytomas (EVNs) based on tumor location (parenchymal vs. sellar) and histological subtype (typical vs. atypica...

Intraoperative blood pressure management strategies and postoperative outcomes in patients undergoing noncardiac surgery: a systematic review and meta-analysis

Abstract Background Current recommendations for intraoperative blood pressure management suggest maintaining mean arterial pressure (MAP) at ≥ 60–65 mmHg to avoid hypotension. However, controversy remains regarding whether higher or individualized MAP targets improve clinically i...

UA-30 ameliorates motor deficits through RalA-mediated mitophagy in ALS mice

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive motor neuron loss, skeletal muscle atrophy, paralysis, and eventually death. Mitochondrial dysfunction plays a pivotal role in ALS pathogenesis, although the precise pathogenic mechani...

Longitudinal Study on Post‐Traumatic Stress Disorder, Anxiety, and Depression Among Medical Staff in China

ABSTRACT Background Evidence of the longitudinal relationship between anxiety, depression, and post‐traumatic stress disorder (PTSD) is not uniform. This study aimed to explore the dynamic changes, independent factors, and bidirectional predictive relationships of anxiety, depres...

Development and validation of an exosomal microRNA prognostic signature for BCLC stage A/B hepatocellular carcinoma

Hepatocellular carcinoma (HCC) exhibits remarkable prognostic heterogeneity within identical Barcelona Clinic Liver Cancer (BCLC) stages, thus requiring more precise molecular biomarkers. Exosomal microRNAs (miRNAs) are stable, non-invasive biomarkers that faithfully reflect the...

ECG theoretical knowledge and interpretation competency of arrhythmias in final-year students: a cross-sectional study

Electrocardiography (ECG) is the key method for diagnosing arrhythmias. Nurses' prompt recognition and early clinical decisions can greatly improve patient outcomes, making it essential to develop nursing students' ECG interpretation skills for arrhythmias. This study aims to ass...

An adaptive geometric iterative algorithm for constrained inverse kinematics and motion planning of continuum robots

Continuum robots with floating bases demonstrate exceptional operational capabilities in confined spaces, such as those encountered in medical surgeries and equipment maintenance. However, developing computationally efficient and development-light solutions for their motion and p...

Interfacial Engineering With a Multifunctional LaPO 4 /LaF 3 Coating Enables Durable 4.65 V LiCoO 2 Cathodes With High‐Rate Capability

ABSTRACT High‐power fast‐charging lithium‐ion batteries (LIBs) are indispensable energy sources for electric vehicles and consumer electronics. LiCoO 2 (LCO) offers remarkable energy density and high voltage but suffers from structural degradation and irreversible O3/H1‐3 phase t...

Prognostic immunonutritional indices and the clinical outcome of patients with traumatic brain injury: a systematic review and meta-analysis

Adverse immunonutritional status has been increasingly recognized as a prognostic factor in patients with traumatic brain injury (TBI). This systematic review and meta-analysis evaluated the associations between immunonutritional status—defined by a low prognostic nutritional ind...

Probabilistic transient stability assessment of power systems with renewable energy using a bounded-Transformer embedding fault severity rules

The increasing penetration of renewable energy introduces significant uncertainty into modern power systems, posing an unpredictable challenge to their stable operation. However, conventional transient stability assessment methods only provide a deterministic result, ignoring the...

Local anesthetic systemic toxicity with liposomal bupivacaine: a case series and literature review

Local Anesthetic Systemic Toxicity (LAST) is an uncommon complication, with manifestations ranging from mild, non-specific neurological symptoms to severe cardiac arrest. Toxicity specifically associated with liposomal bupivacaine is even more rarely documented in the literature....

Development and internal validation of a nomogram for visualising multidimensional correlates of baseline suicide‑attempt history among hospitalized adolescents and young adults with mental disorders

Suicide is prevalent among adolescents and young adults with mental disorders (AYAMD). Identifying factors associated with suicide‑attempt history and characterising risk profiles are essential for targeted suicide prevention in this high‑risk inpatient population. The study incl...

Mortality-trained MRI brain age acceleration mediates sex-specific associations between health-related phenotypes and incident dementia

Abstract Background Brain age acceleration (BAA) has emerged as a promising neuroimaging marker of brain health and neurodegeneration. However, most existing brain age models are trained to predict chronological age, which may not be the most clinically relevant target. In this s...

Robustness of 4D-optimized intensity-modulated proton radiation therapy and proton arc radiation therapy for stereotactic arrhythmia radio-ablation against cardiorespiratory motion

Background Stereotactic arrhythmia radioablation (STAR) is an emerging noninvasive treatment for refractory ventricular tachycardia. Proton therapy offers dosimetric advantages, but pencil-beam scanning is motion-sensitive. This study used an extended cardiac-torso (XCAT)-based 4...

Iron Single-Atom Catalyst Boosting Dried Blood Spots Digestion for High-Throughput Detection of Arsenic and Cadmium

Abstract Herein, a novel Fenton-like digestion strategy has been developed for undiluted, rapid, and high-throughput digestion of DBS samples. The key of this strategy is the development of a blood collection card loaded with iron single-atom catalysts (Fe-SACs). Then, approximat...

Vanadium‐Vacancy‐Induced Atomically Polarized Heterojunctions for Synergistic Bioenergetic Pathogen Disruption and Peripheral Nerve Regeneration

ABSTRACT Drug‐resistant bacterial infections and persistent oxidative stress severely impair nerve endings in burn wounds, presenting a formidable clinical challenge. Current treatment modalities generally fail to achieve simultaneous pathogenic eradication and neuro‐regeneration...