Sichuan University

Freestanding Hierarchical‐Porous BCZT Thin Films Enable Efficient Ultrasonic Energy Harvesting in Soft Tissue

ABSTRACT Excellent electromechanical properties of piezoceramic thin films facilitate ultrasonic energy harvesting in bioelectronic systems. However, most piezoceramic thin films are fragile and cannot maintain mechanical integrity under deformation, hindering their application i...

Serum miR-378d is associated with liver stiffness and fibrosis risk in patients with metabolic dysfunction-associated steatotic liver disease

Tissue biopsy is the gold standard for diagnosing metabolic dysfunction-associated steatohepatitis (MASH), but it is invasive and time-consuming to analyze. This paper aimed to explore the association between serum miR-378d and liver stiffness and fibrosis risk in patients with m...

Clinical predictors of tracheobronchial tuberculosis and associated airway stenosis among patients with pulmonary tuberculosis: a study from Southwestern China

To investigate the clinical characteristics and predictors of tracheobronchial tuberculosis (TBTB) in southwestern China. This single-centre retrospective study included 1,999 patients with confirmed PTB who presented to the outpatient or inpatient departments of West China Hospi...

OAF Blocks SIAH1‐Mediated Degradation of SCPX, a Therapeutic Strategy for MASLD

Metabolic dysfunction-associated steatotic liver disease (MASLD) poses an increasing threat to global public health. Currently approved drugs for MASLD, such as resmetirom and semaglutide, have demonstrated clinical efficacy. However, their use is associated with notable adverse...

The platelet-to-high-density lipoprotein cholesterol ratio as a potential biomarker linking tobacco exposure to accelerated reproductive aging in women

Female reproductive aging, commonly reflected by menopausal age and reproductive lifespan, is influenced by environmental exposures and metabolic health, and tobacco exposure has been associated with earlier menopause and shortened reproductive lifespan. Because this association...

High‐Temperature Alloys in Aeroengines: Damage and Fracture Insights From Micromechanical Modeling

ABSTRACT High‐temperature alloys are the cornerstone of aeroengine hot‐section components, where extreme thermomechanical conditions give rise to intricate damage and fracture behaviors that critically limit the structural integrity of whole aeroengines. Generally, Ni‐based super...

Long‐term efficacy of adjunctive cenobamate: Open‐label extension of a randomized, placebo‐controlled study in a multinational Asian population

OBJECTIVE: This study was undertaken to assess long-term efficacy, safety, and tolerability of adjunctive cenobamate in an open-label extension (OLE) of a randomized, double-blind, placebo-controlled, dose-response study (NCT04557085; YKP3089C035 [Study C035]) in Asian patients w...

Identification and characterization of ethR and ethA genes impacting the sensitivity of Mycobacterium abscessus to ethionamide

ABSTRACT Mycobacterium abscessus is a rapidly growing non-tuberculous mycobacterium with rising global incidence. This pathogen exhibits intrinsic resistance to most antibiotics, presenting a major public health threat. Ethionamide (ETH) requires bioactivation by monooxygenase Et...

Dissymmetrical planar gratings enabled actively chiral perfect absorber

Chiral perfect absorbers (CPAs) can completely absorb one kind of circularly-polarized light while reflecting the other, and have potential applications in fields such as chiral Fabry–Pérot cavity, chiral light emission, and chiral biosensors. In this work, we present a high-perf...

Construction of a preliminary quality indicator framework for palliative care nursing services for terminal cancer patients in China

Standardized nursing service quality evaluation is crucial to address regional disparities and optimize palliative care outcomes in China, yet a structured indicator framework remains lacking. To develop a preliminary SERVQUAL-informed, consensus-based indicator framework for pal...

Metabolomic Profiling of Telomere Length: Associations with Aging-related Phenotypes and Modifiable Lifestyle Factors in Chinese Older Adults

BACKGROUND: Telomere length (TL) is a well-established biomarker of cellular senescence, yet the metabolic profile of TL and its associations with aging-related phenotypes and responses to modifiable lifestyle factors remain unclear. METHODS: TL was measured using quantitative re...

Recent Advances in Electrochemical Aptamer Sensors: Materials Design, Antifouling Strategies, and Toward Miniaturized and Wearable Applications

Electrochemical aptamer sensors integrate the molecular recognition capability of aptamers with electrochemical or electronic signal readout, offering promising tools for environmental monitoring, clinical diagnostics, point-of-care testing, and continuous molecular monitoring. H...

Fast Generation of Feasible Unit Commitment Schedules Based on Standardized Net-Load Trajectory Similarity and Historical Schedule Transfer

High penetration of wind and photovoltaic generation reshapes power system net-load profiles and increases the computational burden of repeatedly solving security-constrained unit commitment problems under multiple renewable scenarios. This paper proposes a fast schedule generati...

Risk factors for surgical site infection after internal fixation for thoracolumbar fractures

The purpose of this study was to investigate the risk factors for surgical site infection (SSI) after internal fixation by posterior approach in patients with thoracolumbar fractures. According to whether SSI occurred after internal fixation, patients were divided into SSI group...

Dynamic asymptotic dimension growth for group actions and groupoids

We introduce the notion of dynamic asymptotic dimension growth for actions of discrete groups on compact spaces, and more generally for locally compact étale groupoids. Moreover, we demonstrate that the asymptotic dimension growth for a discrete metric space of bounded geometry i...

Dibutyl phthalate disrupts ESR1-GPX4 redox signaling and aggravates ovarian dysfunction in a PCOS-like mouse model

Dibutyl phthalate (DBP), a widely used phthalate plasticizer, has been implicated in reproductive toxicity, but the molecular mechanisms by which experimental DBP exposure affects ovarian granulosa-cell function remain incompletely defined. In an exploratory clinical cohort, urin...

A Systematic Transparency Assessment Framework for Life Cycle Background Database to Address Three-Level Black Boxes

Life cycle background database (LCBD) is central to carbon footprint and life cycle assessment (LCA) modeling, yet transparency remains inconsistent across mainstream (ecoinvent, GaBi, USLCI) and emerging (TianGong, HiQLCD) databases. A lack of unified disclosure standards result...

Functional effects of microbial metabolites in dental caries

Dental caries is a multifactorial disease primarily driven by the metabolic activity of microorganisms within oral biofilms. The carious process begins when fermentable carbohydrates are metabolized by microbes, leading to the production of organic acids that lower the local pH a...

Hepatitis B surface antigen clearance rate with pegylated interferon-α therapy in different chronic hepatitis B virus infection populations: A systematic review and meta-analysis

BACKGROUND: Chronic hepatitis B virus (HBV) infection is an urgent public health issue, particularly in endemic regions of Asia and sub-Saharan Africa. Achieving hepatitis B surface antigen (HBsAg) clearance significantly reduces the risk of hepatocellular carcinoma. Pegylated in...

A Cross‐Kingdom Counter‐Mimicry Nanozyme Reverses Fungal‐Induced Neutrophil Paralysis and Establishes Protective Immune Memory

ABSTRACT Recurrent fungal infections caused by Candida albicans remain a formidable clinical challenge due to the pathogen's sophisticated orchestration of immune evasion. Herein, we report a “kill‐and‐reset” nano‐platform comprising a CuFe dual‐atom nanozyme core encapsulated wi...