Sichuan University

Mortality-trained MRI brain age acceleration mediates sex-specific associations between health-related phenotypes and incident dementia

Abstract Background Brain age acceleration (BAA) has emerged as a promising neuroimaging marker of brain health and neurodegeneration. However, most existing brain age models are trained to predict chronological age, which may not be the most clinically relevant target. In this s...

Iron Single-Atom Catalyst Boosting Dried Blood Spots Digestion for High-Throughput Detection of Arsenic and Cadmium

Abstract Herein, a novel Fenton-like digestion strategy has been developed for undiluted, rapid, and high-throughput digestion of DBS samples. The key of this strategy is the development of a blood collection card loaded with iron single-atom catalysts (Fe-SACs). Then, approximat...

Local anesthetic systemic toxicity with liposomal bupivacaine: a case series and literature review

Local Anesthetic Systemic Toxicity (LAST) is an uncommon complication, with manifestations ranging from mild, non-specific neurological symptoms to severe cardiac arrest. Toxicity specifically associated with liposomal bupivacaine is even more rarely documented in the literature....

Development and internal validation of a nomogram for visualising multidimensional correlates of baseline suicide‑attempt history among hospitalized adolescents and young adults with mental disorders

Suicide is prevalent among adolescents and young adults with mental disorders (AYAMD). Identifying factors associated with suicide‑attempt history and characterising risk profiles are essential for targeted suicide prevention in this high‑risk inpatient population. The study incl...

Interfacial Engineering With a Multifunctional LaPO 4 /LaF 3 Coating Enables Durable 4.65 V LiCoO 2 Cathodes With High‐Rate Capability

ABSTRACT High‐power fast‐charging lithium‐ion batteries (LIBs) are indispensable energy sources for electric vehicles and consumer electronics. LiCoO 2 (LCO) offers remarkable energy density and high voltage but suffers from structural degradation and irreversible O3/H1‐3 phase t...

Nanoscale visualization of plasmon-enhanced hydrogen activation on a Pt(111) surface

Abstract Efficient H 2 activation under mild conditions is crucial for achieving energy-efficient catalytic hydrogenation, but this remains a major challenge. Here we demonstrate nanoscale visualization of plasmon-enhanced H 2 activation on Pt(111) at room temperature under visib...

Vanadium‐Vacancy‐Induced Atomically Polarized Heterojunctions for Synergistic Bioenergetic Pathogen Disruption and Peripheral Nerve Regeneration

ABSTRACT Drug‐resistant bacterial infections and persistent oxidative stress severely impair nerve endings in burn wounds, presenting a formidable clinical challenge. Current treatment modalities generally fail to achieve simultaneous pathogenic eradication and neuro‐regeneration...

Task-specific physiological signatures of perceptual and cognitive workload under cockpit noise: implications for pilot state monitoring and training

Cockpit noise is a common operational stressor that can affect pilots' mental workload and performance. This study examined whether multimodal physiological measures could show task-demand-dependent physiological signatures under cockpit-noise interference, and whether these resp...

Multi-omics mapping of TIMP1-associated stromal–myeloid remodeling in autoimmune gastritis and gastric cancer

Abstract Background Autoimmune gastritis (AIG) is a chronic immune-mediated atrophic disease that can induce cancer-related epithelial remodeling, although its association with gastric adenocarcinoma depends on histological and clinical modifiers. Gastric cancer (GC) progression...

Hierarchical Bonding Induced Promising Thermoelectric Performance in Monoclinic Cs2SnSe3.

Thermoelectric materials capable of directly converting heat into electricity are of great interest for sustainable energy utilization and waste-heat recovery. Here, we systematically investigate the structural, vibrational, thermal transport, and electronic transport properties...

The Impact of Financial Literacy on Clean Cooking Fuel Choice Among Rural Households: Evidence from China

Promoting clean cooking fuel adoption among rural households is critical for China’s rural energy transition. However, existing studies have largely overlooked the role of endogenous cognitive capabilities, particularly financial literacy, in shaping household energy choices. To...

An All-in-One Optical Emission Platform for On-Site Sensitive Detection of Selenium in Selenium-Enriched Food: Integrating Digestion, HS-SPME, and Microplasma OES

Abstract The narrow margin between selenium (Se) deficiency and toxicity demands rapid and reliable methods for monitoring Se levels in Se-enriched foods. In this work, we present an all-in-one optical emission platform that integrates in situ sample digestion, derivatization wit...

Resilient Load Frequency Control for Gas–Electricity Coupling Systems Against Gas Pressure False Data Injection Attacks

The coupling of power and natural gas infrastructures introduces gas-side constraints and cyberattack risks into load frequency control (LFC). This paper proposes an auxiliary Kalman filter (AKF)-based tube-based MPC (TMPC) framework for gas–electricity coupling systems under gas...

Glutaredoxin 1 facilitates colitis recovery by controlling glutathionylation and activity of STAT6 in M2 macrophages

Inflammatory bowel disease (IBD) is characterized by oxidative stress and intractable inflammation. Current therapeutic strategies are far from satisfactory because of its not fully understood pathogenesis. M2 macrophages can promote inflammation resolution and tissue repair, and...

Tuning H2O-Engaged Redox Reaction Pathway via Water Orientation in Aqueous Batteries

Abstract Aqueous battery research has long focused on ionic behavior during reactions but has largely neglected the essential role of reactive water, hindering the mechanistic understanding and limiting breakthroughs in battery performance. Herein, we establish an H2O-engaged per...

Minimally invasive surgery without a uterine manipulator versus open radical hysterectomy for early-stage cervical cancer: A retrospective propensity-score-matched single-center cohort study

Objective: To evaluate the surgical outcomes and oncological safety of minimally invasive radical hysterectomy (MIS-RH) without uterine manipulator versus open radical hysterectomy (O-RH) for early-stage cervical cancer (CC).Methods: This retrospective propensity score-matched co...

The Impact of Big Data on Corporate Energy Consumption Intensity: AI Technology and ESG Performance

ABSTRACT Big data have become an increasingly important production factor in the digital economy. Although the resource‐based view (RBV) emphasizes the rarity of strategic resources, the growing accessibility of big data challenges this traditional perspective. Under conditions o...

The Watchful Eye: Government Accounting Supervision and Its Effects on Supply Chain Finance

ABSTRACT This study investigates the impact of government accounting supervision on the adoption of supply chain finance (SCF) among Chinese listed firms. Using a difference‐in‐differences (DID) approach and a comprehensive dataset spanning 1999 to 2022, we find robust evidence t...

Research on the statistical damage model for advance abutment pressure distribution and the evolution of mining-induced stress in deep coal mining

This study addresses the unclear distribution characteristics of advance abutment pressure and mining-induced stress evolution during deep coal mining. A theoretical model for advance abutment pressure was established by coupling the statistical damage constitutive relationship o...

Family resilience and its influencing factors among families of children with malignant tumors during initial chemotherapy: a cross-sectional study

Abstract Background During the primary chemotherapy of pediatric malignant tumors, the physical and mental health of family members can be seriously affected. Family resilience has been shown to be a protective factor. Objectives To investigate family resilience in families with...