Sağlık Bilimleri Üniversitesi

Association of Monocyte Subsets with Carotid Artery Stenosis Severity

Background and Objectives: This study aimed to investigate the association between circulating monocyte subset profiles and carotid artery stenosis (CAS) severity and to examine their relationships with inflammatory and atherosclerosis-related parameters. Materials and Methods: T...

The Frontal QRS-T Angle and Cardiovascular Disease: A Narrative Review of Electrophysiological Basis, Measurement, and Clinical Utility

The QRS-T angle quantifies the divergence between the vectors of ventricular depolarization and repolarization and is regarded as a surrogate for global heterogeneity of ventricular repolarization. Its frontal-plane variant, calculated as the absolute difference between the autom...

Artificial intelligence in eating disorder research: a scoping review with bibliometric analysis of trends, methodologies, and translational readiness (2016–2025)

Abstract Purpose Artificial intelligence (AI) applications in eating disorder research have expanded rapidly, yet the structure, scope, and translational readiness of this literature have not been systematically mapped. This study aimed to characterise publication trends, AI meth...

Early systemic inflammatory indices and postoperative SIRS after percutaneous nephrolithotomy under spinal versus general anaesthesia: a prospective cohort study

Abstract Objective Percutaneous nephrolithotomy (PCNL) may induce an early systemic inflammatory response. This study compared perioperative changes in systemic inflammatory indices between patients undergoing elective PCNL under spinal or general anaesthesia and explored the rel...

Drain versus no-drain thyroidectomy: a tertiary center experience with a retrospective cohort

The necessity of routine drain placement after thyroidectomy remains a subject of debate. This study aimed to determine whether the use of a drain is necessary irrespective of etiology and whether it prevents early or late postoperative complications. This single-center retrospec...

Doxorubicin and 4‐Hydroperoxycyclophosphamide Alter Mitochondrial Dynamics and miR‐34 Expression in Spermatogonia and Spermatocytes In Vitro

Doxorubicin (DOX) and cyclophosphamide (CP) are widely used chemotherapeutic agents with known gonadotoxic effects. Since miRNAs play a key role in the transcriptional regulation of spermatogenesis, they are suggested as biomarkers for male infertility. This study aimed to invest...

How appropriate are ChatGPT-5’s answers to acne questions?

Online conversational tools have become increasingly common sources of health information, with many patients seeking acne advice through such platforms. Although they may enhance awareness and encourage early consultation, their medical reliability remains uncertain. Because acn...

Orbitozygomatic-transsylvian approach to the insula: microsurgical anatomy and endoscopic correlation using the fiber-separation technique

Insular surgery remains technically demanding because of the region’s deep location and intimate relationships with the middle cerebral artery complex and surrounding white matter pathways. Safe resection requires precise understanding of vascular landmarks and subcortical functi...

Clinical Utility of the Atherogenic Plasma Index for Identifying Atherogenic Dyslipidemia: A Large Cross-Sectional Analysis Stratified by Sex and Thyroid Status

Background: The atherogenic plasma index (AIP) has emerged as a promising marker reflecting the balance between triglyceride (TG)-rich lipoproteins and high-density lipoprotein cholesterol (HDL-C). However, its clinical utility in identifying atherogenic dyslipidemia (AD), partic...

The effects of hyperbaric oxygen therapy and mitochondrial transplantation on cisplatin toxicity

Cisplatin is an effective chemotherapeutic agent with dose-limiting toxicity in non-target tissues. Hyperbaric oxygen therapy (HBOT) and mitochondrial transplantation (MitoTr) have been explored as supportive strategies in preclinical models. We examined whether HBOT and/or MitoT...

Association of blood parameters and ratios with aseptic loosening after total knee arthroplasty

This study aimed to evaluate the association of blood parameters and ratios with knee prosthesis loosening in patients after knee arthroplasty. A total of 221 patient files having knee prosthesis attempting to our clinic between 2018 and 2022 were retrospectively examined. Patien...

Performance-based functional assessment in ankylosing spondylitis: Clinical utility and validation of the Back Performance Scale (BPS-TR)

Background Self-report questionnaires are commonly used to assess functional status in patients with ankylosing spondylitis (AS). However, these instruments may not fully reflect patients’ actual physical performance. The Back Performance Scale (BPS-TR) may provide a more objecti...

Association Between Nasal Septal Deviation Types and Eustachian Tube Function: A Prospective Observational Study

OBJECTIVE: This study aimed to objectively and subjectively evaluate the effect of nasal septal deviation (NSD) types, classified according to the Baumann system, on Eustachian tube function. METHODS: A total of 107 NSD patients (78 males, 29 females; mean age: 35.39 ± 9.55 years...

From Metabolism to Molecular Phenotype: Carbonic Anhydrase IX–Targeted [ 68 Ga]Ga-DPI-4452 PET/CT in Renal Cell Carcinoma: A Prospective Multicenter Comparison with [ 18 F]FDG PET/CT

The objective of this study was to prospectively compare the diagnostic performance, lesion detection capability, and clinical staging impact of [68Ga]Ga-DPI-4452 PET/CT with that of [18F]FDG PET/CT in renal cell carcinoma (RCC) using a multicenter design. Methods: Sixty-eight pa...

Microbiological monitoring of scuba cylinders under routine filling and seasonal diving conditions

Introduction: The aim of this study was to monitor the microbiological status of the inner surfaces of scuba cylinders under routine air filling conditions and to assess whether microbiological contamination emerges or persists over time. Methods: A prospective longitudinal micro...

Psychological Well-Being, Dispositional Hope, and Contentment with Life Among Public Hospital Physicians in Türkiye’s Black Sea Region: A Cross-Sectional Study

Background: Physicians work under demanding conditions that may affect their psychological functioning and evaluations of life. Positive psychological resources, particularly dispositional hope, may be relevant to the association between psychological well-being and contentment w...

The relationship of mediterranean diet adherence, family nutrition and physical activity practices, and BMI with oral health in children

Lifestyle-related factors play an important role in the oral health of children. This study examined the associations between Mediterranean diet adherence, physical activity, body mass index (BMI), and oral health in a pediatric population. A descriptive cross-sectional study was...

AN OVERVIEW OF CURRENT RESEARCH ON THE DEVELOPMENT OF ANTHRAQUINONES AS ANTICANCER AGENTS

Objective: In this study, some scientific studies on anthraquinone compounds that have been synthesized in recent years and have been found to have high in vitro and in vivo anticancer activity are summarized. It is aimed to contribute to the design and development of new anthraq...

Clinical and Therapeutic Effects of Adjacent Organ Invasion in Gastrointestinal Stromal Tumor (GIST) Cases

Background: This retrospective study aimed to investigate the clinical and therapeutic effects of adjacent organ invasion in gastrointestinal stromal tumor (GIST) cases. Methods: The files of 114 GIST patients from various centers who underwent surgery by the principal investigat...

Relationships between Continuous Glucose Monitoring-Derived Glycemic Parameters and Early Retinal Vascular Changes in Children with Type 1 Diabetes Mellitus

Objective: This study investigated relationships between continuous glucose monitoring (CGM)-derived metrics and early retinal vascular changes in children having type-1 diabetes mellitus (T1DM) with no clinically-visible diabetic retinopathy (T1DM-noR). Methods: Forty-two T1DM-n...