Sağlık Bilimleri Üniversitesi

From climate change worry to mindful eating for planetary health: a cross-sectional study of eating-related eco-concern

Climate change worry is increasingly discussed as a psychological response to environmental change, yet its relationship with food-specific ecological concern and mindful eating is not well understood. This study examined the association between climate change worry and expanded...

Neonatal Niemann–Pick type C: a case series integrating clinical findings, structural modeling and ACMG-based variant interpretation

Abstract Background Niemann–Pick disease type C (NPC) is a rare autosomal recessive lysosomal storage disorder that can present in the neonatal period with cholestasis and hepatosplenomegaly, making early diagnosis challenging. We report a case series of three neonates evaluated...

Nutritional risk and life satisfaction in older adults: a cross-sectional analysis using the NUFFE-TR scale

This study aimed to investigate the association between nutritional risk and life satisfaction in community-dwelling older adults. A cross-sectional web-based survey was conducted with 779 adults aged ≥ 65 years. Nutritional status was assessed using the Turkish version of the Nu...

Investigation of mandibular cortical and trabecular bone in secondary polycythemia: case-control study

This study aimed to assess differences in mandibular cortical index (MCI) scores and fractal dimension (FD) values of mandibular trabecular bone between patients with secondary polycythemia and healthy controls using panoramic radiographs. A retrospective study was conducted with...

Comparison of Methylprednisolone and Dexamethasone in Their Interaction With Sugammadex in Pediatric Patients: A Randomized Controlled Trial

ABSTRACT Background Sugammadex may interact with steroidal compounds; however, comparative clinical data on different peri‐operative corticosteroids in children are limited. This randomized controlled trial primarily aimed to compare the effect of methylprednisolone and dexametha...

Patient-reported outcomes after revision to the Rigicon® Infla10 inflatable penile prosthesis: a multicentre retrospective registry cohort with a cross-sectional telephone survey

Revision of an inflatable penile prosthesis (IPP) is technically more demanding than primary implantation and usually requires complete IPP removal and replacement. In selected revision cases, patient expectations or surgeon preference may lead to substitution with an IPP from a...

Preoperative Iron Deficiency Anemia and Frailty in Geriatric Colorectal Cancer Surgery: A Prospective Observational Study

Objective: Although iron deficiency anemia (IDA) and frailty are common among geriatric surgical patients—frailty has been reported in approximately 31% of patients undergoing colorectal cancer surgery—prospective data on the association between IDA and frailty in patients underg...

Association of Gastric Microbiota with Gastric Cancer in Patients Infected with Helicobacter pylori

Background: The association between Helicobacter pylori and the resident gastric microbiota plays a critical role in gastric carcinogenesis; however, the specific microbial alterations accompanying the transition from chronic inflammation to malignancy remain to be fully elucidat...

Synthesis, Biological Evaluation, Molecular Docking and DFT Studies of Electronically Tuned Benzylidene-Based Schiff Bases

Inspired by the medicinally relevant stilbene scaffold, a series of six electronically tuned benzylidene-based Schiff base derivatives were designed, synthesized, and characterized by FT-IR, 1H NMR, 13C NMR, and ESI-MS analyses. The biological properties of the synthesized compou...

Predictors of One-Year Restenosis After Percutaneous Mitral Balloon Valvuloplasty in Rheumatic Mitral Stenosis: Real-World Data From 555 Patients and the Limited Impact of Periinterventional Transesophageal Echocardiography

OBJECTIVE: Mitral balloon valvuloplasty remains an established first-line treatment for appropriately selected patients with rheumatic mitral stenosis. However, predictors of long-term restenosis and the additional value of periinterventional transesophageal echocardiography rema...

Lipoedema in an adolescent male following valproate discontinuation: a case report

Serkan KEMER et al. "Lipoedema in an adolescent male following valproate discontinuation"p.

The Role of Umbilicocerebral Ratio and Cerebroplacental Ratio in Predicting Adverse Perinatal Outcomes in Women Undergoing Labor Induction

ABSTRACT Purpose To evaluate the predictive value and clinical significance of pre‐induction Doppler blood flow parameters of the umbilical artery (UA) and middle cerebral artery (MCA), as well as cerebroplacental ratio (CPR), and umbilicocerebral ratio (UCR) for fetal distress d...

Extended Reality in Endodontic Education: A Scoping Review of Educational Impact, Clinical Transferability, and Future Directions

BACKGROUND: Combined with haptic feedback systems, extended reality (XR) platforms enable immersive, multisensory learning environments that approximate the tactile, spatial, and proprioceptive demands of endodontic procedures. OBJECTIVE: To map and critically examine the current...

Echinococcus granulosus Genotype and Surgical Outcomes After Cystic Echinococcosis Surgery: A Propensity-Score-Adjusted Retrospective Pilot Cohort Study

Background: Echinococcus granulosus sensu lato comprises several genotypes (G1, G3, G6–G10) that may differ in host range and clinical phenotype, but whether genotype influences localization, cyst size/stage, surgical complexity, or recurrence after cystic echinococcosis (CE) sur...

Absorbable tacker fixation versus non-fixation in totally extraperitoneal inguinal hernia repair: a prospective randomized study on postoperative pain and quality of life

The role of mesh fixation in laparoscopic totally extraperitoneal (TEP) inguinal hernia repair remains controversial. While fixation may increase postoperative pain, concerns about recurrence in larger defects prevent its complete abandonment. This study aimed to compare absorbab...

Direct versus indirect epiglottis elevation during McGrath MAC videolaryngoscopy: a randomized trial of glottic visualization and the hemodynamic response

Videolaryngoscopy is widely used for tracheal intubation. With Macintosh-geometry videolaryngoscopes such as the McGrath MAC, the epiglottis can be elevated indirectly by placing the blade tip in the vallecula, or directly by advancing it beneath the epiglottis. Their relative ef...

Relationship Between Health Literacy and Rational Drug Use in Primary Care

Aim: To determine health literacy and rational drug use levels among adults attending a primary care family health center, quantify their association, and identify independent predictors using multivariable regression analysis. Methods: A cross-sectional study was conducted with...

Baseline Liver Metabolic Health in Newly Diagnosed People Living with HIV Compared with HIV-Negative Controls: Cross-Sectional Findings from the Prospective MASHIV-TR Cohort

Metabolic dysfunction-associated steatotic liver disease (MASLD) is an important comorbidity in people living with HIV (PLWH), yet most data derive from individuals receiving antiretroviral therapy (ART). In the baseline cross-sectional analysis of the prospective multicentre MAS...

Association Between Glycemic Variability and Bone Turnover and the Sema3A Signaling Pathway in Postmenopausal Women with Type 2 Diabetes Mellitus

Background: This study evaluated relationships between glycemic variability, bone turnover markers, Sema3A pathway components, and bone mineral density in postmenopausal women with type 2 diabetes mellitus (T2DM). Methods: In this single-center cross-sectional study with prospect...

Breastfeeding and Supplementary Oral Feeding Methods in Very Preterm Infants: A Prospective Within-Infant Comparison

Background: Very preterm infants often require supplementary oral feeding while direct breastfeeding skills mature. We compared short-term feeding performance and suck-swallow-breath coordination (SSBC) across three oral feeding methods. Materials and Methods: In this prospective...